HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 1497

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HXB2 Location Gag(183-191)
p24(51-59)
DNA(1336..1362)
Gag Epitope Map
Author Location p24(183-191 LAI)
Epitope DLNTMLNTV Epitope Alignment
DLNTMLNTV epitope logo
Epitope Name G5
Subtype B
Species (MHC/HLA) human(B*14)
Immunogen HIV-1 infection
Experimental methods  
Keywords HAART, ART

Notes

References

Mollet2000 L. Mollet, T. S. Li, A. Samri, C. Tournay, R. Tubiana, V. Calvez, P. Debre, C. Katlama, and B. Autran. Dynamics of HIV-specific CD8+ T lymphocytes with changes in viral load. J. Immunol., 165(3):1692-704, 1 Aug 2000. URL: http://www.jimmunol.org/v165n3/1692/1692-abs-frame.html. PubMed ID: 10903781. Show all entries for this paper.


Displaying record number 194

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HXB2 Location Gag(183-191)
p24(51-59)
DNA(1336..1362)
Gag Epitope Map
Author Location p24(183-191 LAI)
Epitope DLNTMLNTV Epitope Alignment
DLNTMLNTV epitope logo
Subtype B
Species (MHC/HLA) human(B14, Cw8)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Johnson1992 R. P. Johnson, A. Trocha, T. M. Buchanan, and B. D. Walker. Identification of Overlapping HLA Class I-Restricted Cytotoxic T Cell Epitopes in a Conserved Region of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein: Definition of Minimum Epitopes and Analysis of the Effects of Sequence Variation. J. Exp. Med., 175:961-971, 1992. Fine mapping and mutational analysis of gp41 epitopes: ERYLKDQQL, HLA B14 and YLKDQQLL, HLA B8. PubMed ID: 1372650. Show all entries for this paper.

Nixon1988 D. Nixon, A. Townsend, J. Elvin, C. Rizza, J. Gallway, and A. McMichael. HIV-1 Gag-Specific Cytotoxic T Lymphocytes Defined with Recombinant Vaccinia Virus and Synthetic Peptides. Nature, 336:484-487, 1988. p24 KRWIILGLNKIVRMY. PubMed ID: 2461519. Show all entries for this paper.


Displaying record number 195

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HXB2 Location Gag(183-191)
p24(51-59)
DNA(1336..1362)
Gag Epitope Map
Author Location p24
Epitope DLNTMLNTV Epitope Alignment
DLNTMLNTV epitope logo
Show epitope variants
Species (MHC/HLA) human(B14, Cw8)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords subtype comparisons, HIV exposed persistently seronegative (HEPS)

Notes

References

RowlandJones1998b S. Rowland-Jones, T. Dong, P. Krausa, J. Sutton, H. Newell, K. Ariyoshi, F. Gotch, S. Sabally, T. Corrah, J. Kimani, K. MacDonald, F. Plummer, J. Ndinya-Achola, H. Whittle, and A. McMichael. The Role of Cytotoxic T Cells in HIV Infection. Dev. Biol. Stand., 92:209-214, 1998. In this paper CTL response to previously defined conserved epitopes was found in exposed but uninfected prostitutes in Nairobi. Subtypes A and D are circulating in this regions, and the reactive epitopes tended to be conserved. Similarly previous studies in the Gambia showed that exposed but uninfected prostitutes tended to have B35 presented CTL epitopes conserved between HIV-1 and HIV-2. It was suggested that what was special about B35 is simply that it presents epitopes found both in HIV-1 and HIV-2. PubMed ID: 9554277. Show all entries for this paper.


Displaying record number 196

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HXB2 Location Gag(183-191)
p24(51-59)
DNA(1336..1362)
Gag Epitope Map
Author Location p24( subtype B)
Epitope DLNTMLNTV Epitope Alignment
DLNTMLNTV epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(B*14:02, Cw8)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords subtype comparisons

Notes

References

Rowland-Jones1998 S. L. Rowland-Jones, T. Dong, K. R. Fowke, J. Kimani, P. Krausa, H. Newell, T. Blanchard, K. Ariyoshi, J. Oyugi, E. Ngugi, J. Bwayo, K. S. MacDonald, A. J. McMichael, and F. A. Plummer. Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi. J. Clin. Invest., 102(9):1758-65, 1 Nov 1998. PubMed ID: 9802890. Show all entries for this paper.


Displaying record number 191

Download this epitope record as JSON.

HXB2 Location Gag(183-191)
p24(51-59)
DNA(1336..1362)
Gag Epitope Map
Author Location p24(183-191 LAI)
Epitope DLNTMLNTV Epitope Alignment
DLNTMLNTV epitope logo
Subtype B
Species (MHC/HLA) human(Cw8)
Immunogen HIV-1 infection
Experimental methods  
Keywords review

Notes

References

McMichael1994 A. J. McMichael and B. D. Walker. Cytotoxic T Lymphocytes Epitopes: Implications for HIV Vaccine. AIDS, 8S:S155-S173, 1994. Comprehensive review summarizing CTL epitopes that have known HLA type and are fine mapped to indicate epitope boundaries. Anchor residues are indicated when known for different HLA restricted epitopes. Includes a summary of the published literature, as well as much work that was in press or submitted for publication. Show all entries for this paper.


Displaying record number 192

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HXB2 Location Gag(183-191)
p24(51-59)
DNA(1336..1362)
Gag Epitope Map
Author Location p24
Epitope DLNTMLNTV Epitope Alignment
DLNTMLNTV epitope logo
Species (MHC/HLA) chimpanzee
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Santra1999 S. Santra, P. N. Fultz, and N. L. Letvin. Virus-Specific Cytotoxic T Lymphocytes in Human Immunodeficiency Virus Type 1-Infected Chimpanzees. J. Virol., 73:7065-7069, 1999. PubMed ID: 10400811. Show all entries for this paper.


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