HIV molecular immunology database
Found 6 matching records:
Download this epitope record as JSON.
HXB2 Location | Gag(405-413) p2p7p1p6(42-50) DNA(2002..2028) |
Gag Epitope Map |
---|---|---|
Author Location | p15(42-50 SF2) | |
Epitope |
CRAPRKKGC
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B14) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | B14 | |
Experimental methods | ||
Keywords | immunodominance |
Yu2002a Xu G. Yu, Hong Shang, Marylyn M. Addo, Robert L. Eldridge, Mary N. Phillips, Margaret E. Feeney, Daryld Strick, Christian Brander, Philip J. R. Goulder, Eric S. Rosenberg, Bruce D. Walker, Marcus Altfeld, and HIV Study Collaboration. Important Contribution of p15 Gag-Specific Responses to the Total Gag-Specific CTL Responses. AIDS, 16(3):321-328, 15 Feb 2002. PubMed ID: 11834942. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(405-413) p2p7p1p6(42-50) DNA(2002..2028) |
Gag Epitope Map |
---|---|---|
Author Location | p15(42-50) | |
Epitope |
CRAPRKKGC
|
Epitope Alignment
|
Species (MHC/HLA) | human(B14) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(405-413) p2p7p1p6(42-50) DNA(2002..2028) |
Gag Epitope Map |
---|---|---|
Author Location | ( B consensus) | |
Epitope |
CRAPRKKGC
|
Epitope Alignment
|
Epitope Name | CC9 | |
Subtype | B | |
Species (MHC/HLA) | human(B14) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A28, A29, B14, B44, Cw8 | |
Experimental methods | Chromium-release assay, Cytokine production, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining | |
Keywords | assay or method development, memory cells, characterizing CD8+ T cells |
Lichterfeld2004b Mathias Lichterfeld, Xu G. Yu, Michael T. Waring, Stanley K. Mui, Mary N. Johnston, Daniel Cohen, Marylyn M. Addo, John Zaunders, Galit Alter, Eunice Pae, Daryld Strick, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, and Marcus Altfeld. HIV-1-Specific Cytotoxicity Is Preferentially Mediated by a Subset of CD8+ T Cells Producing both Interferon-gamma and Tumor Necrosis Factor-alpha. Blood, 104(2):487-394, 15 Jul 2004. PubMed ID: 15059848. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(405-413) p2p7p1p6(42-50) DNA(2002..2028) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(405-413) | |
Epitope |
CRAPRKKGC
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B14) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A28, A29, B14, B44, Cw8 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords |
Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(405-413) p2p7p1p6(42-50) DNA(2002..2028) |
Gag Epitope Map |
---|---|---|
Author Location | Gag(405-413) | |
Epitope |
CRAPRKKGC
|
Epitope Alignment
|
Epitope Name | CC9 | |
Species (MHC/HLA) | human(C*08) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Gag(405-413) p2p7p1p6(42-50) DNA(2002..2028) |
Gag Epitope Map |
---|---|---|
Author Location | p2p7p1p6(405-413) | |
Epitope |
CRAPRKKGC
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human | |
Immunogen | engineered | |
Experimental methods | Other, Relative replication capacity assay | |
Keywords | assay or method development, protective allele |
Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.