HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 52268

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HXB2 Location Gag(405-413)
p2p7p1p6(42-50)
DNA(2002..2028)
Gag Epitope Map
Author Location p15(42-50 SF2)
Epitope CRAPRKKGC Epitope Alignment
CRAPRKKGC epitope logo
Subtype B
Species (MHC/HLA) human(B14)
Immunogen HIV-1 infection
Patient MHC/HLA B14
Experimental methods  
Keywords immunodominance

Notes

References

Yu2002a Xu G. Yu, Hong Shang, Marylyn M. Addo, Robert L. Eldridge, Mary N. Phillips, Margaret E. Feeney, Daryld Strick, Christian Brander, Philip J. R. Goulder, Eric S. Rosenberg, Bruce D. Walker, Marcus Altfeld, and HIV Study Collaboration. Important Contribution of p15 Gag-Specific Responses to the Total Gag-Specific CTL Responses. AIDS, 16(3):321-328, 15 Feb 2002. PubMed ID: 11834942. Show all entries for this paper.


Displaying record number 52552

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HXB2 Location Gag(405-413)
p2p7p1p6(42-50)
DNA(2002..2028)
Gag Epitope Map
Author Location p15(42-50)
Epitope CRAPRKKGC Epitope Alignment
CRAPRKKGC epitope logo
Species (MHC/HLA) human(B14)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 53366

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HXB2 Location Gag(405-413)
p2p7p1p6(42-50)
DNA(2002..2028)
Gag Epitope Map
Author Location ( B consensus)
Epitope CRAPRKKGC Epitope Alignment
CRAPRKKGC epitope logo
Epitope Name CC9
Subtype B
Species (MHC/HLA) human(B14)
Immunogen HIV-1 infection
Patient MHC/HLA A28, A29, B14, B44, Cw8
Experimental methods Chromium-release assay, Cytokine production, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords assay or method development, memory cells, characterizing CD8+ T cells

Notes

References

Lichterfeld2004b Mathias Lichterfeld, Xu G. Yu, Michael T. Waring, Stanley K. Mui, Mary N. Johnston, Daniel Cohen, Marylyn M. Addo, John Zaunders, Galit Alter, Eunice Pae, Daryld Strick, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, and Marcus Altfeld. HIV-1-Specific Cytotoxicity Is Preferentially Mediated by a Subset of CD8+ T Cells Producing both Interferon-gamma and Tumor Necrosis Factor-alpha. Blood, 104(2):487-394, 15 Jul 2004. PubMed ID: 15059848. Show all entries for this paper.


Displaying record number 53569

Download this epitope record as JSON.

HXB2 Location Gag(405-413)
p2p7p1p6(42-50)
DNA(2002..2028)
Gag Epitope Map
Author Location Gag(405-413)
Epitope CRAPRKKGC Epitope Alignment
CRAPRKKGC epitope logo
Subtype B
Species (MHC/HLA) human(B14)
Immunogen HIV-1 infection
Patient MHC/HLA A28, A29, B14, B44, Cw8
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.


Displaying record number 59563

Download this epitope record as JSON.

HXB2 Location Gag(405-413)
p2p7p1p6(42-50)
DNA(2002..2028)
Gag Epitope Map
Author Location Gag(405-413)
Epitope CRAPRKKGC Epitope Alignment
CRAPRKKGC epitope logo
Epitope Name CC9
Species (MHC/HLA) human(C*08)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 62829

Download this epitope record as JSON.

HXB2 Location Gag(405-413)
p2p7p1p6(42-50)
DNA(2002..2028)
Gag Epitope Map
Author Location p2p7p1p6(405-413)
Epitope CRAPRKKGC Epitope Alignment
CRAPRKKGC epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


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