HIV molecular immunology database
Found 20 matching records:
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Species (MHC/HLA) | human(B*18) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Subtype | B | |
Species (MHC/HLA) | human(B27) | |
Immunogen | HIV-1 infection | |
Country | Netherlands | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | computational epitope prediction |
Schellens2008 Ingrid M. M. Schellens, Can Kesmir, Frank Miedema, Debbie van Baarle, and José A. M. Borghans. An Unanticipated Lack of Consensus Cytotoxic T Lymphocyte Epitopes in HIV-1 Databases: The Contribution of Prediction Programs. AIDS, 22(1):33-37, 2 Jan 2008. PubMed ID: 18090389. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | S00052: A*01, A*25, B*18, B*57, C*06, C*12 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | dynamics, chronic infection |
Balamurugan2017 Arumugam Balamurugan, Deon Claiborne, Hwee L. Ng, and Otto O. Yang. HIV-1 Epitope Variability Is Associated with T Cell Receptor Repertoire Instability and Breadth. J. Virol., 91(16), 15 Aug 2017. PubMed ID: 28592539. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | Vpr-AW9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | HAART, ART |
Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | ||
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | escape |
Bailey2006 Justin R. Bailey, Thomas M. Williams, Robert F. Siliciano, and Joel N. Blankson. Maintenance of Viral Suppression in HIV-1-Infected HLA-B*57+ Elite Suppressors Despite CTL Escape Mutations. J. Exp. Med., 203(5):1357-1369, 15 May 2006. PubMed ID: 16682496. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | vprAV9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Country | Kenya, United Kingdom | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | TCR usage, structure, characterizing CD8+ T cells |
Gillespie2006 Geraldine M. A. Gillespie, Guillaume Stewart-Jones, Jaya Rengasamy, Tara Beattie, Job J. Bwayo, Francis A. Plummer, Rupert Kaul, Andrew J. McMichael, Philippa Easterbrook, Tao Dong, E. Yvonne Jones, and Sarah L. Rowland-Jones. Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection. J. Immunol., 177(6):3893-3902, 15 Sep 2006. PubMed ID: 16951352. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Country | Barbados, Haiti, Jamaica | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | mother-to-infant transmission, elite controllers |
Schneidewind2009 Arne Schneidewind, Yanhua Tang, Mark A. Brockman, Elizabeth G. Ryland, Jacqueline Dunkley-Thompson, Julianne C. Steel-Duncan, M. Anne St. John, Joseph A. Conrad, Spyros A. Kalams, Francine Noel, Todd M. Allen, Celia D. Christie, and Margaret E. Feeney. Maternal Transmission of Human Immunodeficiency Virus Escape Mutations Subverts HLA-B57 Immunodominance but Facilitates Viral Control in the Haploidentical Infant. J. Virol., 83(17):8616-8627, Sep 2009. PubMed ID: 19515764. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | in vitro stimulation or selection, HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | TCR usage, assay or method development, chronic infection |
Balamurugan2010 Arumugam Balamurugan, Hwee L. Ng, and Otto O. Yang. Rapid T Cell Receptor Delineation Reveals Clonal Expansion Limitation of the Magnitude of the HIV-1-Specific CD8+ T Cell Response. J. Immunol., 185(10):5935-5942, 15 Nov 2010. PubMed ID: 20944001. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Country | Canada | |
Experimental methods | Other | |
Keywords | characterizing CD8+ T cells, elite controllers |
Peretz2011 Yoav Peretz, Olivia Marra, Réjean Thomas, Danielle Legault, Pierre Côté, Mohamed-Rachid Boulassel, Danielle Rouleau, Jean-Pierre Routy, Rafick-Pierre Sékaly, Christos M Tsoukas, Cécile Tremblay, and Nicole F. Bernard. Relative Contribution of HIV-Specific Functional Lymphocyte Subsets Restricted by Protective and Non-Protective HLA Alleles. Viral Immunol, 24(3):189-198, Jun 2011. PubMed ID: 21668360. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | AW9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Country | Germany | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | elite controllers |
Jessen2014 Heiko Jessen, Todd M. Allen, and Hendrik Streeck. How a Single Patient Influenced HIV Research — 15-Year Follow-Up. N. Engl. J. Med., 370(7):682-683, 13 Feb 2014. PubMed ID: 24521131. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | B57-AW9(vpr) | |
Species (MHC/HLA) | human(B*57) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | AC-108: A*02, B*57, B*61, C*03, C*06 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining | |
Keywords | acute/early infection, protective allele |
Altfeld2003a Marcus Altfeld, Marylyn M. Addo, Eric S. Rosenberg, Frederick M. Hecht, Paul K. Lee, Martin Vogel, Xu G. Yu, Rika Draenert, Mary N. Johnston, Daryld Strick, Todd M. Allen, Margaret E. Feeney, James O. Kahn, Rafick P. Sekaly, Jay A. Levy, Jürgen K. Rockstroh, Philip J. Goulder, and Bruce D. Walker. Influence of HLA-B57 on Clinical Presentation and Viral Control during Acute HIV-1 Infection. AIDS, 17(18):2581-2591, 5 Dec 2003. PubMed ID: 14685052. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Subtype | B | |
Species (MHC/HLA) | human(B57) | |
Immunogen | HIV-1 infection | |
Country | Netherlands | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | computational epitope prediction |
Schellens2008 Ingrid M. M. Schellens, Can Kesmir, Frank Miedema, Debbie van Baarle, and José A. M. Borghans. An Unanticipated Lack of Consensus Cytotoxic T Lymphocyte Epitopes in HIV-1 Databases: The Contribution of Prediction Programs. AIDS, 22(1):33-37, 2 Jan 2008. PubMed ID: 18090389. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B57) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A1, A3, B57, B7, Cw6, Cw7 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords |
Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | ||
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*58:01, B57) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | responses in children, mother-to-infant transmission, escape |
Feeney2005a Margaret E. Feeney, Yanhua Tang, Katja Pfafferott, Kathleen A. Roosevelt, Rika Draenert, Alicja Trocha, Xu G. Yu, Cori Verrill, Todd Allen, Corey Moore, Simon Mallal, Sandra Burchett, Kenneth McIntosh, Stephen I. Pelton, M. Anne St. John, Rohan Hazra, Paul Klenerman, Marcus Altfeld, Bruce D. Walker, and Philip J. R. Goulder. HIV-1 Viral Escape in Infancy Followed by Emergence of a Variant-Specific CTL Response. J. Immunol., 174(12):7524-7530, 15 Jun 2005. PubMed ID: 15944251. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Subtype | B, C | |
Species (MHC/HLA) | human(B57, B63) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, HLA cross-presentation, optimal epitope, novel epitope |
Frahm2005a Nicole Frahm, Sharon Adams, Photini Kiepiela, Caitlyn H. Linde, Hannah S. Hewitt, Mathias Lichterfeld, Kaori Sango, Nancy V. Brown, Eunice Pae, Alysse G. Wurcel, Marcus Altfeld, Margaret E. Feeney, Todd M. Allen, Timothy Roach, M. Anne St. John, Eric S. Daar, Eric Rosenberg, Bette Korber, Francesco Marincola, Bruce D. Walker, Philip J. R. Goulder, and Christian Brander. HLA-B63 Presents HLA-B57/B58-Restricted Cytotoxic T-Lymphocyte Epitopes and Is Associated with Low Human Immunodeficiency Virus Load. J. Virol., 79(16):10218-10225, Aug 2005. PubMed ID: 16051815. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(29-38 SF2) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*57:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | acute/early infection |
Altfeld2001c M. Altfeld, M. M. Addo, R. L. Eldridge, X. G. Yu, S. Thomas, A. Khatri, D. Strick, M. N. Phillips, G. B. Cohen, S. A. Islam, S. A. Kalams, C. Brander, P. J. Goulder, E. S. Rosenberg, B. D. Walker, and The HIV Study Collaboration.. Vpr is preferentially targeted by CTL during HIV-1 infection. J. Immunol., 167(5):2743-52, 1 Sep 2001. URL: http://www.jimmunol.org/cgi/content/full/167/5/2743. PubMed ID: 11509618. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(29-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(B*57:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | early-expressed proteins |
Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*57:01) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(30-38) DNA(5646..5672) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(30-38) | |
Epitope |
AVRHFPRIW
|
Epitope Alignment
|
Epitope Name | AW9 | |
Species (MHC/HLA) | human(C*14) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.