HIV molecular immunology database
Found 14 matching records:
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(894-903) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | AK10 | |
Species (MHC/HLA) | human(A*03) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Integrase(179-188) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Species (MHC/HLA) | human(A*03:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(894-903) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | AK10 | |
Species (MHC/HLA) | human(A*11) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Integrase(179-188) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*11) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other | |
Keywords | assay or method development, optimal epitope |
Wang2007 Shaoyang Wang, Yongtao Sun, Song Zhai, Yan Zhuang, Shuguang Zhao, Whenzhen Kang, Xinhong Li, Dedong Huang, Xu G. Yu, Bruce D. Walker, and Marcus A. Altfeld. Identification of HLA-A11-Restricted HIV-1-Specific Cytotoxic T-Lymphocyte Epitopes in China. Curr. HIV Res., 5(1):119-128, Jan 2007. PubMed ID: 17266563. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(894-903 93TH253 subtype CRF01) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | P894-903 | |
Subtype | CRF01_AE | |
Species (MHC/HLA) | human(A*11) | |
Immunogen | HIV-1 exposed seronegative | |
Experimental methods | ||
Keywords | HIV exposed persistently seronegative (HEPS) |
Bond2001 K. B. Bond, B. Sriwanthana, T. W. Hodge, A. S. De Groot, T. D. Mastro, N. L. Young, N. Promadej, J. D. Altman, K. Limpakarnjanarat, and J. M. McNicholl. An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais. AIDS Res. Hum. Retroviruses, 17(8):703-17, 20 May 2001. PubMed ID: 11429111. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Integrase | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | A11-AK10(Int) | |
Species (MHC/HLA) | human(A11) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | rate of progression, immunodominance, early-expressed proteins |
Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | 1264 | |
Subtype | multiple | |
Species (MHC/HLA) | human(A11) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | 202001: A25, A68, B18, B27; 606001: A1, A68, B15, B40, Cw3; 523001: A11, A3, B14, B51, Cw8 | |
Country | United States | |
Experimental methods | T-cell Elispot | |
Keywords | binding affinity, supertype, computational epitope prediction, immunodominance, HLA cross-presentation, novel epitope |
DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Integrase | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | AK10(Integrase) | |
Subtype | B | |
Species (MHC/HLA) | human(A11, A3) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Integrase(179-188 LAI) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Subtype | B | |
Species (MHC/HLA) | human(A*11:01) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Fukada1999 K. Fukada, Y. Chujoh, H. Tomiyama, K. Miwa, Y. Kaneko, S. Oka, and M. Takiguchi. HLA-A*1101-Restricted Cytotoxic T Lymphocyte Recognition of HIV-1 Pol Protein. AIDS, 13:1413-1414, 1999. PubMed ID: 10449296. Show all entries for this paper.
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(894-903) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Subtype | B, CRF01_AE | |
Species (MHC/HLA) | human(A*11:01) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | subtype comparisons |
Fukada2002 Katsuhiko Fukada, Hiroko Tomiyama, Chantapong Wasi, Tomoko Matsuda, Shigeru Kusagawa, Hironori Sato, Shinichi Oka, Yutaka Takebe, and Masafumi Takiguchi. Cytotoxic T-cell Recognition of HIV-1 Cross-Clade and Clade-Specific Epitopes in HIV-1-Infected Thai and Japanese Patients. AIDS, 16(5):701-711, 29 Mar 2002. PubMed ID: 11964526. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Pol(894-903) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | AK10 | |
Species (MHC/HLA) | human(A*24) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Pol | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | 1264 | |
Subtype | multiple | |
Species (MHC/HLA) | human(A3) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A23, A3, B49, B57; A24, A3, B27, B57, C*18 | |
Country | United States | |
Experimental methods | T-cell Elispot | |
Keywords | binding affinity, computational epitope prediction, novel epitope |
DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Integrase(179-188) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | A3-AK10 Pol | |
Subtype | B | |
Species (MHC/HLA) | human(A3) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | supervised treatment interruptions (STI), escape, early treatment, superinfection |
Altfeld2002a Marcus Altfeld, Todd M. Allen, Xu G. Yu, Mary N. Johnston, Deepak Agrawal, Bette T. Korber, David C. Montefiori, David H. O'Connor, Ben T. Davis, Paul K. Lee, Erica L. Maier, Jason Harlow, Philip J. R. Goulder, Christian Brander, Eric S. Rosenberg, and Bruce D. Walker. HIV-1 Superinfection Despite Broad CD8+ T-Cell Responses Containing Replication of the Primary Virus. Nature, 420(6914):434-439, 28 Nov 2002. PubMed ID: 12459786. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Pol(894-903) Integrase(179-188) DNA(4764..4793) |
Pol Epitope Map |
---|---|---|
Author Location | Integrase(894-904) | |
Epitope |
AVFIHNFKRK
|
Epitope Alignment
|
Epitope Name | A3-AK10 | |
Subtype | B | |
Species (MHC/HLA) | human(A3) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A3, B7, Cw7 | |
Experimental methods | ||
Keywords | dynamics, supervised treatment interruptions (STI), acute/early infection |
Yu2002b Xu G. Yu, Marylyn M. Addo, Eric S. Rosenberg, William R. Rodriguez, Paul K. Lee, Cecily A. Fitzpatrick, Mary N. Johnston, Daryld. Strick, Philip J. R. Goulder, Bruce D. Walker, and Marcus Altfeld. Consistent Patterns in the Development and Immunodominance of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T-Cell Responses Following Acute HIV-1 Infection. J. Virol., 76(17):8690-8701, Sep 2002. PubMed ID: 12163589. Show all entries for this paper.