HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 14 matching records:

Displaying record number 59556

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Pol(894-903)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name AK10
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 52528

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Integrase(179-188)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Species (MHC/HLA) human(A*0301)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 59555

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Pol(894-903)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name AK10
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 55243

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Integrase(179-188)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Subtype B
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords assay or method development, optimal epitope

Notes

References

Wang2007 Shaoyang Wang, Yongtao Sun, Song Zhai, Yan Zhuang, Shuguang Zhao, Whenzhen Kang, Xinhong Li, Dedong Huang, Xu G. Yu, Bruce D. Walker, and Marcus A. Altfeld. Identification of HLA-A11-Restricted HIV-1-Specific Cytotoxic T-Lymphocyte Epitopes in China. Curr. HIV Res., 5(1):119-128, Jan 2007. PubMed ID: 17266563. Show all entries for this paper.


Displaying record number 1727

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Pol(894-903 93TH253 subtype CRF01)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name P894-903
Subtype CRF01_AE
Species (MHC/HLA) human(A*11)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords HIV exposed persistently seronegative (HEPS)

Notes

References

Bond2001 K. B. Bond, B. Sriwanthana, T. W. Hodge, A. S. De Groot, T. D. Mastro, N. L. Young, N. Promadej, J. D. Altman, K. Limpakarnjanarat, and J. M. McNicholl. An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais. AIDS Res. Hum. Retroviruses, 17(8):703-17, 20 May 2001. PubMed ID: 11429111. Show all entries for this paper.


Displaying record number 54258

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Integrase
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name A11-AK10(Int)
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 56427

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Integrase
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name AK10(Integrase)
Subtype B
Species (MHC/HLA) human(A11, A3)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 52863

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Pol
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name 1264
Subtype multiple
Species (MHC/HLA) human(A11, A3, A68)
Immunogen HIV-1 infection
Patient MHC/HLA A1, A68, B15, B40, Cw03; A11, A3, B14, B51, Cw13, Cw8; A25, A68, B18, B27
Country United States
Experimental methods T-cell Elispot
Keywords binding affinity, supertype, computational epitope prediction, immunodominance, HLA cross-presentation

Notes

References

DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.


Displaying record number 1192

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Integrase(179-188 LAI)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Subtype B
Species (MHC/HLA) human(A*1101)
Immunogen  
Experimental methods  
Keywords optimal epitope

Notes

References

Fukada1999 K. Fukada, Y. Chujoh, H. Tomiyama, K. Miwa, Y. Kaneko, S. Oka, and M. Takiguchi. HLA-A*1101-Restricted Cytotoxic T Lymphocyte Recognition of HIV-1 Pol Protein. AIDS, 13:1413-1414, 1999. PubMed ID: 10449296. Show all entries for this paper.

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 52101

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Pol(894-903)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Subtype B, CRF01_AE
Species (MHC/HLA) human(A*1101)
Immunogen HIV-1 infection
Experimental methods  
Keywords subtype comparisons

Notes

References

Fukada2002 Katsuhiko Fukada, Hiroko Tomiyama, Chantapong Wasi, Tomoko Matsuda, Shigeru Kusagawa, Hironori Sato, Shinichi Oka, Yutaka Takebe, and Masafumi Takiguchi. Cytotoxic T-cell Recognition of HIV-1 Cross-Clade and Clade-Specific Epitopes in HIV-1-Infected Thai and Japanese Patients. AIDS, 16(5):701-711, 29 Mar 2002. PubMed ID: 11964526. Show all entries for this paper.


Displaying record number 59554

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Pol(894-903)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name AK10
Species (MHC/HLA) human(A*24)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 52895

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Pol
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name 1264
Subtype multiple
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A23, A3, B49, B57; A24, A3, B27, B57, Cw13, Cw18
Country United States
Experimental methods T-cell Elispot
Keywords binding affinity, computational epitope prediction

Notes

References

DeGroot2003 Anne S. De Groot, Bill Jesdale, William Martin, Caitlin Saint Aubin, Hakima Sbai, Andrew Bosma, Judy Lieberman, Gail Skowron, Fadi Mansourati, and Kenneth H. Mayer. Mapping Cross-Clade HIV-1 Vaccine Epitopes Using a Bioinformatics Approach. Vaccine, 21(27-30):4486-4504, 1 Oct 2003. PubMed ID: 14505932. Show all entries for this paper.


Displaying record number 52828

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Integrase(179-188)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Show epitope variants
Epitope Name A3-AK10 Pol
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords supervised treatment interruptions (STI), escape, early treatment, superinfection

Notes

References

Altfeld2002a Marcus Altfeld, Todd M. Allen, Xu G. Yu, Mary N. Johnston, Deepak Agrawal, Bette T. Korber, David C. Montefiori, David H. O'Connor, Ben T. Davis, Paul K. Lee, Erica L. Maier, Jason Harlow, Philip J. R. Goulder, Christian Brander, Eric S. Rosenberg, and Bruce D. Walker. HIV-1 Superinfection Despite Broad CD8+ T-Cell Responses Containing Replication of the Primary Virus. Nature, 420(6914):434-439, 28 Nov 2002. PubMed ID: 12459786. Show all entries for this paper.


Displaying record number 52148

HXB2 Location Pol(894-903)
Integrase(179-188)
DNA(4764..4793)
Pol Epitope Map
Author Location Integrase(894-904)
Epitope AVFIHNFKRK Epitope Alignment
AVFIHNFKRK epitope logo
Epitope Name A3-AK10
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Patient MHC/HLA A3, B7, Cw7
Experimental methods  
Keywords dynamics, supervised treatment interruptions (STI), acute/early infection

Notes

References

Yu2002b Xu G. Yu, Marylyn M. Addo, Eric S. Rosenberg, William R. Rodriguez, Paul K. Lee, Cecily A. Fitzpatrick, Mary N. Johnston, Daryld. Strick, Philip J. R. Goulder, Bruce D. Walker, and Marcus Altfeld. Consistent Patterns in the Development and Immunodominance of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8+ T-Cell Responses Following Acute HIV-1 Infection. J. Virol., 76(17):8690-8701, Sep 2002. PubMed ID: 12163589. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Operated by Los Alamos National Security, LLC, for the U.S. Department of Energy's National Nuclear Security Administration
Copyright © 2006-2017 LANS LLC All rights reserved | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health