HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 56958

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HXB2 Location Gag(83-91)
p17(83-91)
DNA(1036..1062)
Gag Epitope Map
Author Location Gag
Epitope ATLYCVHQK Epitope Alignment
ATLYCVHQK epitope logo
Subtype C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


Displaying record number 58016

Download this epitope record as JSON.

HXB2 Location Gag(83-91)
p17(83-91)
DNA(1036..1062)
Gag Epitope Map
Author Location Gag
Epitope ATLYCVHQK Epitope Alignment
ATLYCVHQK epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen vaccine
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type adenovirus type 5 (Ad5), DNA prime with Ad5 boost
Vaccine strain B clade IIIB, B clade JRFL, B clade CAM-1
Vaccine component Gag, Nef, Pol

Notes

References

Li2011a Fusheng Li, Adam C. Finnefrock, Sheri A. Dubey, Bette T. M. Korber, James Szinger, Suzanne Cole, M. Juliana McElrath, John W. Shiver, Danilo R. Casimiro, Lawrence Corey, and Steven G Self. Mapping HIV-1 Vaccine Induced T-Cell Responses: Bias Towards Less-Conserved Regions and Potential Impact on Vaccine Efficacy in the Step Study. PLoS One, 6(6):e20479, 2011. PubMed ID: 21695251. Show all entries for this paper.


Displaying record number 62888

Download this epitope record as JSON.

HXB2 Location Gag(83-91)
p17(83-91)
Gag Epitope Map
Author Location Gag
Epitope ATLYCVHQK Epitope Alignment
ATLYCVHQK epitope logo
Species (MHC/HLA) human
Immunogen HIV-1 infection, vaccine
Experimental methods Other
Keywords vaccine-induced immune responses

Vaccine Details

Vaccine type polyepitope, adenovirus type 5 (Ad5)
Vaccine component Gag, Nef, Pol

Notes

References

Boppana2020 Sushma Boppana, Andrew Fiore-Gartland, Anju Bansal, and Paul Goepfert. Cross-Reactive CD8 T-Cell Responses Elicited by Adenovirus Type 5-Based HIV-1 Vaccines Contributed to Early Viral Evolution in Vaccine Recipients Who Became Infected. J Virol, 94(2):JVI01632-19 doi, Jan 2020. PubMed ID: 31645444 Show all entries for this paper.


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