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Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 62222

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HXB2 Location Pol(328-336)
RT(173-181)
DNA(3066..3092)
Pol Epitope Map
Author Location Pol(328-366)
Epitope AQNPEIVIY Epitope Alignment
AQNPEIVIY epitope logo
Show epitope variants
Epitope Name Pol-AY9
Subtype C
Species (MHC/HLA) human(A*30)
Immunogen HIV-1 infection
Patient MHC/HLA 517-C: A*30:02, A*68:02, B*15:10, B*42:01, C*03:04, C*17:01; 517-M: A*30:02, A*30:04, B*42:01, B*58:02, C*06:02, C*17:01
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords dynamics, responses in children, mother-to-infant transmission, rate of progression, escape

Notes

References

Leitman2017 Ellen M. Leitman, Christina F. Thobakgale, Emily Adland, M. Azim Ansari, Jayna Raghwani, Andrew J. Prendergast, Gareth Tudor-Williams, Photini Kiepiela, Joris Hemelaar, Jacqui Brener, Ming-Han Tsai, Masahiko Mori, Lynn Riddell, Graz Luzzi, Pieter Jooste, Thumbi Ndung'u, Bruce D. Walker, Oliver G. Pybus, Paul Kellam, Vivek Naranbhai, Philippa C. Matthews, Astrid Gall, and Philip J. R. Goulder. Role of HIV-Specific CD8+ T Cells in Pediatric HIV Cure Strategies after Widespread Early Viral Escape. J. Exp. Med., 214(11):3239-3261, 6 Nov 2017. PubMed ID: 28983013. Show all entries for this paper.


Displaying record number 53328

Download this epitope record as JSON.

HXB2 Location Pol(328-336)
RT(173-181)
DNA(3066..3092)
Pol Epitope Map
Author Location ( C consensus)
Epitope AQNPEIVIY Epitope Alignment
AQNPEIVIY epitope logo
Subtype C
Species (MHC/HLA) human(A*30:02)
Immunogen HIV-1 infection
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords characterizing CD8+ T cells

Notes

References

Kiepiela2004 Photini Kiepiela, Alasdair J. Leslie, Isobella Honeyborne, Danni Ramduth, Christina Thobakgale, Senica Chetty, Prinisha Rathnavalu, Corey Moore, Katja J. Pfafferott, Louise Hilton, Peter Zimbwa, Sarah Moore, Todd Allen, Christian Brander, Marylyn M. Addo, Marcus Altfeld, Ian James, Simon Mallal, Michael Bunce, Linda D. Barber, James Szinger, Cheryl Day, Paul Klenerman, James Mullins, Bette Korber, Hoosen M. Coovadia, Bruce D. Walker, and Philip J. R. Goulder. Dominant Influence of HLA-B in Mediating the Potential Co-Evolution of HIV and HLA. Nature, 432(7018):769-775, 9 Dec 2004. LA-UR 04-5920. PubMed ID: 15592417. Show all entries for this paper.


Displaying record number 61822

Download this epitope record as JSON.

HXB2 Location Pol(328-336)
RT(173-181)
DNA(3066..3092)
Pol Epitope Map
Author Location  
Epitope AQNPEIVIY Epitope Alignment
AQNPEIVIY epitope logo
Epitope Name AY9
Species (MHC/HLA) human
Immunogen HIV-1 infection, vaccine
Patient MHC/HLA VID410: A*30:02, B*18:01, B*57:03, C*07:01, C*18:01
Country United Kingdom
Experimental methods Intracellular cytokine staining, Other
Keywords vaccine-induced immune responses

Notes

References

Borthwick2017 Nicola Borthwick, Zhansong Lin, Tomohiro Akahoshi, Anuska Llano, Sandra Silva-Arrieta, Tina Ahmed, Lucy Dorrell, Christian Brander, Hayato Murakoshi, Masafumi Takiguchi, and Tomáš Hanke. Novel, In-Natural-Infection Subdominant HIV-1 CD8+ T-Cell Epitopes Revealed in Human Recipients of Conserved-Region T-Cell Vaccines. PLoS One, 12(4):1-19, 2017. PubMed ID: 28448594. Show all entries for this paper.


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