HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 10 matching records:

Displaying record number 62533

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location Pol(188-198)
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Epitope Name AK11
Subtype B
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Patient MHC/HLA S00009: A*03, A*26, B*15, B*38, C*03, C*12
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords dynamics, chronic infection

Notes

References

Balamurugan2017 Arumugam Balamurugan, Deon Claiborne, Hwee L. Ng, and Otto O. Yang. HIV-1 Epitope Variability Is Associated with T Cell Receptor Repertoire Instability and Breadth. J. Virol., 91(16), 15 Aug 2017. PubMed ID: 28592539. Show all entries for this paper.


Displaying record number 57385

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location Pol(188-198)
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Epitope Name AK11
Subtype B
Species (MHC/HLA) human(A*03)
Immunogen in vitro stimulation or selection, HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords TCR usage, assay or method development, chronic infection

Notes

References

Balamurugan2010 Arumugam Balamurugan, Hwee L. Ng, and Otto O. Yang. Rapid T Cell Receptor Delineation Reveals Clonal Expansion Limitation of the Magnitude of the HIV-1-Specific CD8+ T Cell Response. J. Immunol., 185(10):5935-5942, 15 Nov 2010. PubMed ID: 20944001. Show all entries for this paper.


Displaying record number 1775

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location RT(33-43)
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Species (MHC/HLA) human(A*03)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression, acute/early infection

Notes

References

Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.


Displaying record number 410

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location RT(33-43)
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Species (MHC/HLA) human(A*03:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Haas1998 G. Haas, A. Samri, E. Gomard, A. Hosmalin, J. Duntze, J. M. Bouley, H. G. Ihlenfeldt, C. Katlama, and B. Autran. Cytotoxic T Cell Responses to HIV-1 Reverse Transcriptase, Integrase and Protease. AIDS, 12(12):1427-1436, 1998. PubMed ID: 9727563. Show all entries for this paper.


Displaying record number 411

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location RT(33-43)
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Species (MHC/HLA) human(A*03:01)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

Notes

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 56423

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location RT
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Epitope Name AK11(RT)
Subtype B
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 54246

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location RT
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Epitope Name A3-AK11(RT)
Species (MHC/HLA) human(A3)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords rate of progression, immunodominance, early-expressed proteins

Notes

References

Altfeld2006 Marcus Altfeld, Elizabeth T. Kalife, Ying Qi, Hendrik Streeck, Mathias Lichterfeld, Mary N. Johnston, Nicole Burgett, Martha E. Swartz, Amy Yang, Galit Alter, Xu G. Yu, Angela Meier, Juergen K. Rockstroh, Todd M. Allen, Heiko Jessen, Eric S. Rosenberg, Mary Carrington, and Bruce D. Walker. HLA Alleles Associated with Delayed Progression to AIDS Contribute Strongly to the Initial CD8+ T Cell Response against HIV-1. PLoS Med., 3(10):e403, Oct 2006. PubMed ID: 17076553. Show all entries for this paper.


Displaying record number 59543

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location Pol(188-198)
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Epitope Name AK11
Species (MHC/HLA) human(B*07)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59544

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HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location Pol(188-198)
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Epitope Name AK11
Species (MHC/HLA) human(C*02)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 62836

Download this epitope record as JSON.

HXB2 Location Pol(188-198)
RT(33-43)
DNA(2646..2678)
Pol Epitope Map
Author Location RT(33-43)
Epitope ALVEICTEMEK Epitope Alignment
ALVEICTEMEK epitope logo
Epitope Name AK11
Subtype B, C
Species (MHC/HLA) human
Immunogen HIV-1 infection, engineered
Experimental methods Other, Relative replication capacity assay
Keywords acute/early infection, HLA associated polymorphism, chronic infection, protective allele

Notes

References

Ojwach2018 Doty B. A. Ojwach, Daniel MacMillan, Tarylee Reddy, Vladimir Novitsky, Zabrina L. Brumme, Mark A. Brockman, Thumbi Ndung'u, and Jaclyn K. Mann. Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection. J. Virol., 92(19), 1 Oct 2018. PubMed ID: 29997209. Show all entries for this paper.


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