HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 1396

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HXB2 Location Nef(42-50)
DNA(8920..8946)
Nef Epitope Map
Author Location Nef(44-52 HXB3)
Epitope ALTSSNTAA Epitope Alignment
ALTSSNTAA epitope logo
Species (MHC/HLA) mouse(A*02:01)
Immunogen vaccine
Experimental methods  
Keywords binding affinity, computational epitope prediction

Vaccine Details

Vaccine type DNA, peptide
Vaccine strain B clade HXB3
Vaccine component Nef
Adjuvant Complete Freund's Adjuvant (CFA)

Notes

References

Sandberg2000 J. K. Sandberg, A. C. Leandersson, C. Devito, B. Kohleisen, V. Erfle, A. Achour, M. Levi, S. Schwartz, K. Karre, B. Wahren, and J. Hinkula. Human immunodeficiency virus type 1 Nef epitopes recognized in HLA-A2 transgenic mice in response to DNA and peptide immunization. Virology, 273(1):112-9, 20 Jul 2000. PubMed ID: 10891413. Show all entries for this paper.


Displaying record number 53175

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HXB2 Location Nef(42-50)
DNA(8920..8946)
Nef Epitope Map
Author Location Nef(42-50)
Epitope ALTSSNTAA Epitope Alignment
ALTSSNTAA epitope logo
Epitope Name Nef42-50
Species (MHC/HLA) human, humanized mouse(A2)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords responses in children, immunodominance, characterizing CD8+ T cells

Notes

References

Chandwani2004 R. Chandwani, K. A. Jordan, B. L. Shacklett, E. Papasavvas, L. J. Montaner, M. G. Rosenberg, D. F. Nixon, and J. K. Sandberg. Limited Magnitude and Breadth in the HLA-A2-Restricted CD8 T-Cell Response to Nef in Children with Vertically Acquired HIV-1 Infection. Scand. J. Immunol., 59(1):109-114, Jan 2004. PubMed ID: 14723629. Show all entries for this paper.


Displaying record number 58953

Download this epitope record as JSON.

HXB2 Location Nef(42-50)
DNA(8920..8946)
Nef Epitope Map
Author Location Nef(42-50)
Epitope ALTSSNTAA Epitope Alignment
ALTSSNTAA epitope logo
Subtype C
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA CAP063: A*02:01, A*23:01, B*45:01, C*04:01, C*16:01
Country South Africa
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords escape, acute/early infection

Notes

References

Abrahams2013 Melissa-Rose Abrahams, Florette K. Treurnicht, Nobubelo K. Ngandu, Sarah A. Goodier, Jinny C. Marais, Helba Bredell, Ruwayhida Thebus, Debra de Assis Rosa, Koleka Mlisana, Cathal Seoighe, Salim Abdool Karim, Clive M. Gray, and Carolyn Williamson. Rapid, Complex Adaptation of Transmitted HIV-1 Full-Length Genomes in Subtype C-Infected Individuals with Differing Disease Progression. AIDS, 27(4):507-518, 20 Feb 2013. PubMed ID: 23370465. Show all entries for this paper.


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