Found 5 matching records:
Download this epitope record as JSON.
HXB2 Location | Vpr(59-67) DNA(5733..5759) |
Vpr Epitope Map |
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Author Location | Vpr(59-67) | |
Epitope |
ALIRILQQL
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Epitope Alignment
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Show epitope variants | ||
Epitope Name | AL9 | |
Subtype | B | |
Species (MHC/HLA) | human(A*02:01) | |
Immunogen | HIV-1 infection | |
Country | Australia | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | escape, HLA associated polymorphism |
Keane2012 Niamh M. Keane, Steven G. Roberts, Coral-Ann M. Almeida, Tanya Krishnan, Abha Chopra, Emma Demaine, Rebecca Laird, Monika Tschochner, Jonathan M. Carlson, Simon Mallal, David Heckerman, Ian James, and Mina John. High-Avidity, High-IFN-gamma-Producing CD8 T-Cell Responses following Immune Selection during HIV-1 Infection. Immunol. Cell Biol., 90(2):224-234, Feb 2012. PubMed ID: 21577229. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(59-67) DNA(5733..5759) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(59-67) | |
Epitope |
ALIRILQQL
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | AL9 | |
Subtype | B | |
Species (MHC/HLA) | human(A2) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A11, A2, B18, B44, C*12, Cw5 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining | |
Keywords | escape |
Allen2005 Todd M. Allen, Xu G. Yu, Elizabeth T. Kalife, Laura L. Reyor, Mathias Lichterfeld, Mina John, Michael Cheng, Rachel L. Allgaier, Stanley Mui, Nicole Frahm, Galit Alter, Nancy V. Brown, Mary N. Johnston, Eric S. Rosenberg, Simon A. Mallal, Christian Brander, Bruce D. Walker, and Marcus Altfeld. De Novo Generation of Escape Variant-Specific CD8+ T-Cell Responses Following Cytotoxic T-Lymphocyte Escape in Chronic Human Immunodeficiency Virus Type 1 Infection. J. Virol., 79(20):12952-12960, Oct 2005. PubMed ID: 16188997. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(59-67) DNA(5733..5759) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr | |
Epitope |
ALIRILQQL
|
Epitope Alignment
|
Epitope Name | AL9 | |
Subtype | B | |
Species (MHC/HLA) | human(A2) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A11, A2, B18, B44, C*12, Cw5 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | subtype comparisons, escape, characterizing CD8+ T cells, viral fitness and/or reversion |
Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(59-67) DNA(5733..5759) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(59-67) | |
Epitope |
ALIRILQQL
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human(A2) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay, HLA binding | |
Keywords | escape, acute/early infection, variant cross-reactivity, optimal epitope |
Altfeld2005a Marcus Altfeld, Todd M. Allen, Elizabeth T. Kalife, Nicole Frahm, Marylyn M. Addo, Bianca R. Mothe, Almas Rathod, Laura L. Reyor, Jason Harlow, Xu G. Yu, Beth Perkins, Loren K. Robinson, John Sidney, Galit Alter, Mathias Lichterfeld, Alessandro Sette, Eric S. Rosenberg, Philip J. R. Goulder, Christian Brander, and Bruce D. Walker. The Majority of Currently Circulating Human Immunodeficiency Virus Type 1 Clade B Viruses Fail To Prime Cytotoxic T-Lymphocyte Responses against an Otherwise Immunodominant HLA-A2-Restricted Epitope: Implications for Vaccine Design. J. Virol., 79(8):5000-5005, Apr 2005. PubMed ID: 15795285. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | Vpr(59-67) DNA(5733..5759) |
Vpr Epitope Map |
---|---|---|
Author Location | Vpr(59-67) | |
Epitope |
ALIRILQQL
|
Epitope Alignment
|
Subtype | C | |
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | CAP063: A*02:01, A*23:01, B*45:01, C*04:01, C*16:01 | |
Country | South Africa | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Other | |
Keywords | escape, acute/early infection |
Abrahams2013 Melissa-Rose Abrahams, Florette K. Treurnicht, Nobubelo K. Ngandu, Sarah A. Goodier, Jinny C. Marais, Helba Bredell, Ruwayhida Thebus, Debra de Assis Rosa, Koleka Mlisana, Cathal Seoighe, Salim Abdool Karim, Clive M. Gray, and Carolyn Williamson. Rapid, Complex Adaptation of Transmitted HIV-1 Full-Length Genomes in Subtype C-Infected Individuals with Differing Disease Progression. AIDS, 27(4):507-518, 20 Feb 2013. PubMed ID: 23370465. Show all entries for this paper.
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