HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 6 matching records:

Displaying record number 62276

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HXB2 Location Gag(146-155)
p24(14-23)
DNA(1225..1254)
Gag Epitope Map
Author Location Gag(14-23)
Epitope AISPRTLNAW Epitope Alignment
AISPRTLNAW epitope logo
Show epitope variants
Epitope Name AW10, IW9
Subtype B
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords immunodominance, escape, chronic infection, protective allele

Notes

References

Bansal2007 Anju Bansal, Ling Yue, Joan Conway, Karina Yusim, Jianming Tang, John Kappes, Richard A. Kaslow, Craig M. Wilson, and Paul A. Goepfert. Immunological Control of Chronic HIV-1 Infection: HLA-Mediated Immune Function and Viral Evolution in Adolescents. AIDS, 21(18):2387-2397, 30 Nov 2007. PubMed ID: 18025875. Show all entries for this paper.


Displaying record number 60627

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HXB2 Location Gag(146-155)
p24(14-23)
DNA(1225..1254)
Gag Epitope Map
Author Location p24(14-23)
Epitope AISPRTLNAW Epitope Alignment
AISPRTLNAW epitope logo
Epitope Name AW-10
Subtype B, C
Species (MHC/HLA) human(B*57, B*63)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Tenzer2014 Stefan Tenzer, Hayley Crawford, Phillip Pymm, Robert Gifford, Vattipally B. Sreenu, Mirjana Weimershaus, Tulio de Oliveira, Anne Burgevin, Jan Gerstoft, Nadja Akkad, Daniel Lunn, Lars Fugger, John Bell, Hansjörg Schild, Peter van Endert, and Astrid K. N. Iversen. HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification. Cell Rep., 7(2):448-463, 24 Apr 2014. PubMed ID: 24726370. Show all entries for this paper.


Displaying record number 53489

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HXB2 Location Gag(146-155)
p24(14-23)
DNA(1225..1254)
Gag Epitope Map
Author Location Gag
Epitope AISPRTLNAW Epitope Alignment
AISPRTLNAW epitope logo
Epitope Name IW9
Subtype B
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, escape, characterizing CD8+ T cells, viral fitness and reversion

Notes

References

Allen2005a Todd M. Allen, Marcus Altfeld, Shaun C. Geer, Elizabeth T. Kalife, Corey Moore, Kristin M. O'Sullivan, Ivna DeSouza, Margaret E. Feeney, Robert L. Eldridge, Erica L. Maier, Daniel E. Kaufmann, Matthew P. Lahaie, Laura Reyor, Giancarlo Tanzi, Mary N. Johnston, Christian Brander, Rika Draenert, Jurgen K. Rockstroh, Heiko Jessen, Eric S. Rosenberg, Simon A. Mallal, and Bruce D. Walker. Selective Escape from CD8+ T-Cell Responses Represents a Major Driving Force of Human Immunodeficiency Virus Type 1 (HIV-1) Sequence Diversity and Reveals Constraints on HIV-1 Evolution. J. Virol., 79(21):13239-13249, Nov 2005. PubMed ID: 16227247. Show all entries for this paper.


Displaying record number 61213

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HXB2 Location Gag(146-155)
p24(14-23)
DNA(1225..1254)
Gag Epitope Map
Author Location Gag(254-262)
Epitope AISPRTLNAW Epitope Alignment
AISPRTLNAW epitope logo
Show epitope variants
Epitope Name ISW9
Subtype B
Species (MHC/HLA) human(B*57:02, B*57:03)
Immunogen HIV-1 infection
Experimental methods Other
Keywords review, escape, HLA associated polymorphism

Notes

References

Kloverpris2015a Henrik N. Kløverpris, Alasdair Leslie, and Philip Goulder. Role of HLA Adaptation in HIV Evolution. Front. Immunol., 6:665, 18 Jan 2016. PubMed ID: 26834742. Show all entries for this paper.


Displaying record number 61674

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HXB2 Location Gag(146-155)
p24(14-23)
DNA(1225..1254)
Gag Epitope Map
Author Location Gag(146-155)
Epitope AISPRTLNAW Epitope Alignment
AISPRTLNAW epitope logo
Show epitope variants
Epitope Name Gag-IW9
Subtype C
Species (MHC/HLA) human(B*57:02, B*57:03, B*58:01)
Immunogen HIV-1 infection
Country Botswana, South Africa, United Kingdom, Zimbabwe
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords HLA associated polymorphism

Notes

References

Carlson2012 Jonathan M. Carlson, Jennifer Listgarten, Nico Pfeifer, Vincent Tan, Carl Kadie, Bruce D. Walker, Thumbi Ndung'u, Roger Shapiro, John Frater, Zabrina L. Brumme, Philip J. R. Goulder, and David Heckerman. Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1. J. Virol., 86(9):5230-5243, May 2012. PubMed ID: 22379086. Show all entries for this paper.


Displaying record number 56956

Download this epitope record as JSON.

HXB2 Location Gag(146-155)
p24(14-23)
DNA(1225..1254)
Gag Epitope Map
Author Location Gag
Epitope AISPRTLNAW Epitope Alignment
AISPRTLNAW epitope logo
Subtype A1, CRF02_AG
Species (MHC/HLA) human(B58)
Immunogen HIV-1 infection
Country Sweden
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, vaccine antigen design

Notes

References

Perez2008 Carina L. Pérez, Mette V. Larsen, Rasmus Gustafsson, Melissa M. Norström, Ann Atlas, Douglas F. Nixon, Morten Nielsen, Ole Lund, and Annika C. Karlsson. Broadly Immunogenic HLA Class I Supertype-Restricted Elite CTL Epitopes Recognized in a Diverse Population Infected with Different HIV-1 Subtypes. J. Immunol., 180(7):5092-5100, 1 Apr 2008. PubMed ID: 18354235. Show all entries for this paper.


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