HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 58227

Download this epitope record as JSON.

HXB2 Location Vif(119-127)
DNA(5395..5421)
Vif Epitope Map
Author Location Vif(119-127)
Epitope AIRKAILGR Epitope Alignment
AIRKAILGR epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(A*31:01)
Immunogen HIV-1 infection
Patient MHC/HLA CH040: A*02:01, A*31:01, B*40:01, B*44:02, C*03:02, C*05:01
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining
Keywords dynamics, escape, acute/early infection, autologous responses, characterizing CD8+ T cells

Notes

References

Ferrari2011 Guido Ferrari, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, Steve Self, Sydeaka Watson, Michael R. Betts, Cynthia Gay, Kara McGhee, Pierre Pellegrino, Ian Williams, Georgia D. Tomaras, Barton F. Haynes, Clive M. Gray, Persephone Borrow, Mario Roederer, Andrew J. McMichael, and Kent J. Weinhold. Relationship between Functional Profile of HIV-1 Specific CD8 T Cells and Epitope Variability with the Selection of Escape Mutants in Acute HIV-1 Infection. PLoS Pathog., 7(2):e1001273, 2011. PubMed ID: 21347345. Show all entries for this paper.


Displaying record number 56658

Download this epitope record as JSON.

HXB2 Location Vif(119-127)
DNA(5395..5421)
Vif Epitope Map
Author Location Vif(119-127)
Epitope AIRKAILGR Epitope Alignment
AIRKAILGR epitope logo
Show epitope variants
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA A*02:01, A*31:01, B*40:01, B*44:02, C*03:02, C*05:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords escape, acute/early infection

Notes

References

Goonetilleke2009 Nilu Goonetilleke, Michael K. P. Liu, Jesus F. Salazar-Gonzalez, Guido Ferrari, Elena Giorgi, Vitaly V. Ganusov, Brandon F. Keele, Gerald H. Learn, Emma L. Turnbull, Maria G Salazar, Kent J Weinhold, Stephen Moore, CHAVI Clinical Core B, Norman Letvin, Barton F. Haynes, Myron S. Cohen, Peter Hraber, Tanmoy Bhattacharya, Persephone Borrow, Alan S. Perelson, Beatrice H. Hahn, George M. Shaw, Bette T. Korber, and Andrew J. McMichael. The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection. J. Exp. Med., 206(6):1253-1272, 8 Jun 2009. PubMed ID: 19487423. Show all entries for this paper.


Displaying record number 61055

Download this epitope record as JSON.

HXB2 Location Vif(119-127)
DNA(5395..5421)
Vif Epitope Map
Author Location Vif(119-127)
Epitope AIRKAILGR Epitope Alignment
AIRKAILGR epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA CH040: A*02:01, A*31:01, B*40:01, B*44:02, C*03:02, C*05:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords computational epitope prediction, escape, acute/early infection, mutation acquisition

Notes

References

Barton2016 John P. Barton, Nilu Goonetilleke, Thomas C. Butler, Bruce D. Walker, Andrew J. McMichael, and Arup K. Chakraborty. Relative Rate and Location of Intra-Host HIV Evolution to Evade Cellular Immunity Are Predictable. Nat. Commun., 7:11660, 23 May 2016. PubMed ID: 27212475. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health