HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 11 matching records:

Displaying record number 59535

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location Gag(210-218)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Epitope Name AV9
Species (MHC/HLA) human(A*23)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59536

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location Gag(210-218)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Epitope Name AV9
Species (MHC/HLA) human(B*18)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 59534

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location Gag(210-218)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Epitope Name AV9
Species (MHC/HLA) human(B*35:02, B*35:03, B*53:01)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 53870

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location Gag(210-218)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Show epitope variants
Subtype B
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Patient MHC/HLA A*03, A*24, B*35, B*40
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords acute/early infection, variant cross-reactivity, superinfection

Notes

References

Yang2005 Otto O. Yang, Eric S. Daar, Beth D. Jamieson, Arumugam Balamurugan, Davey M. Smith, Jacqueline A. Pitt, Christos J. Petropoulos, Douglas D. Richman, Susan J. Little, and Andrew J. Leigh Brown. Human Immunodeficiency Virus Type 1 Clade B Superinfection: Evidence for Differential Immune Containment of Distinct Clade B Strains. J. Virol., 79(2):860-868, Jan 2005. PubMed ID: 15613314. Show all entries for this paper.


Displaying record number 59533

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location Gag(210-218)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Epitope Name AV9
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Experimental methods CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay
Keywords rate of progression, optimal epitope, chronic infection

Notes

References

Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.


Displaying record number 56032

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Epitope Name AV9(p24)
Subtype B
Species (MHC/HLA) human(B40)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords chronic infection

Notes

References

Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.


Displaying record number 1961

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(78-86)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Epitope Name Gag-AV9, p24-AV9
Subtype B
Species (MHC/HLA) human(B*40:02)
Immunogen HIV-1 infection
Patient MHC/HLA 01RCH59: A*02:01, A*32:01, B*40:02, B*53:01, C*02:02, C*04:01
Country United States
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay
Keywords novel epitope

Notes

References

Sabbaj2003 Steffanie Sabbaj, Anju Bansal, G. Douglas Ritter, Christopher Perkins, Bradley H. Edwards, Ethan Gough, Jianming Tang, James J. Szinger, Bette Korber, Craig M. Wilson, Richard A. Kaslow, Mark J. Mulligan, and Paul A. Goepfert. Cross-Reactive CD8+ T Cell Epitopes Identified in US Adolescent Minorities. J. Acquir. Immune Defic. Syndr., 33(4):426-438, 1 Aug 2003. PubMed ID: 12869831. Show all entries for this paper.


Displaying record number 52570

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(78-86)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Species (MHC/HLA) human(B*40:02)
Immunogen HIV-1 infection
Experimental methods  
Keywords optimal epitope, A-list

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.


Displaying record number 61535

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(78-86)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Show epitope variants
Epitope Name Gag p24 AV9-6V
Subtype CRF01_AE
Species (MHC/HLA) human(B*40:02)
Immunogen HIV-1 infection
Patient MHC/HLA KI-388: A*02:06, B*40:02
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, variant cross-reactivity, optimal epitope, novel epitope, chronic infection

Notes

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


Displaying record number 62801

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(210-218)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Subtype B
Species (MHC/HLA) human
Immunogen engineered
Experimental methods Other, Relative replication capacity assay
Keywords assay or method development, protective allele

Notes

References

Du2017 Yushen Du, Tian-Hao Zhang, Lei Dai, Xiaojuan Zheng, Aleksandr M. Gorin, John Oishi, Ting-Ting Wu, Janice M. Yoshizawa, Xinmin Li, Otto O. Yang, Otoniel Martinez-Maza, Roger Detels, and Ren Sun. Effects of Mutations on Replicative Fitness and Major Histocompatibility Complex Class I Binding Affinity Are Among the Determinants Underlying Cytotoxic-T-Lymphocyte Escape of HIV-1 Gag Epitopes. mBio, 8(6), 28 Nov 2017. PubMed ID: 29184023. Show all entries for this paper.


Displaying record number 61460

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location Gag(210-218)
Epitope AEWDRVHPV Epitope Alignment
AEWDRVHPV epitope logo
Show epitope variants
Epitope Name AV9-B40
Subtype CRF01_AE
Species (MHC/HLA) human
Immunogen HIV-1 infection
Patient MHC/HLA Subject 4: A*02, A*24, B*13, B*40, C*03, C*08
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, Other
Keywords acute/early infection, kinetics

Notes

References

Jiang2016 Xifeng Jiang, Qiyan Jia, Lu Lu, Fei Yu, Jishen Zheng, Weiguo Shi, Lifeng Cai, Shibo Jiang, and Keliang Liu. A Novel Bispecific Peptide HIV-1 Fusion Inhibitor Targeting the N-Terminal Heptad Repeat and Fusion Peptide Domains in gp41. Amino Acids, 48(12):2867-2873, Dec 2016. PubMed ID: 27631437. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health