HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 8 matching records:

Displaying record number 53421

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HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(78-86)
Epitope AEWDRLHPV Epitope Alignment
AEWDRLHPV epitope logo
Show epitope variants
Epitope Name AEW
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Patient MHC/HLA A2, A68.1, B*07, B*35:03, C*04:01, C*07:02, DQ2, DQ6, DR15, DR17, DR51, DR52
Experimental methods CD4 T-cell Elispot - IFNγ, CD8 T-cell Elispot - IFNγ
Keywords rate of progression, escape

Notes

References

Oxenius2004 Annette Oxenius, David A. Price, Alexandra Trkola, Charles Edwards, Emma Gostick, Hua-Tang Zhang, Philippa J. Easterbrook, Tin Tun, Andrew Johnson, Anele Waters, Edward C. Holmes, and Rodney E. Phillips. Loss of Viral Control in Early HIV-1 Infection Is Temporally Associated with Sequential Escape from CD8+ T Cell Responses and Decrease in HIV-1-Specific CD4+ and CD8+ T Cell Frequencies. J. Infect. Dis., 190(4):713-721, 15 Aug 2004. PubMed ID: 15272399. Show all entries for this paper.


Displaying record number 57071

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HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(78-86 DU422)
Epitope AEWDRLHPV Epitope Alignment
AEWDRLHPV epitope logo
Subtype B
Species (MHC/HLA) human(A2)
Immunogen in vitro stimulation or selection
Experimental methods CD8 T-cell Elispot - IFNγ, Chromium-release assay, Tetramer binding
Keywords dendritic cells

Notes

References

Colleton2009 Bonnie A. Colleton, Xiao-Li Huang, Nada M. Melhem, Zheng Fan, Luann Borowski, Giovanna Rappocciolo, and Charles R. Rinaldo. Primary Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses Induced by Myeloid Dendritic Cells. J. Virol., 83(12):6288-6299, Jun 2009. PubMed ID: 19357176. Show all entries for this paper.


Displaying record number 54856

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HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24( Henan isolate)
Epitope AEWDRLHPV Epitope Alignment
AEWDRLHPV epitope logo
Subtype B
Species (MHC/HLA) human(A2)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords  

Notes

References

Gong2006 Xiaoyan Gong, Xien Gui, Yuxia Zhang, and Po Tien. Screening for CD8 Cytotoxic T Lymphocytes Specific for Gag of Human Immunodeficiency Virus Type 1 Subtype B' Henan Isolate from China and Identification of Novel Epitopes Restricted by the HLA-A2 and HLA-A11 Alleles. J. Gen. Virol., 87(Pt 1):151-158, Jan 2006. PubMed ID: 16361427. Show all entries for this paper.


Displaying record number 55266

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HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(78-86)
Epitope AEWDRLHPV Epitope Alignment
AEWDRLHPV epitope logo
Subtype B
Species (MHC/HLA) human(B*40)
Immunogen HIV-1 infection
Country China
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other
Keywords assay or method development, optimal epitope

Notes

References

Wang2007 Shaoyang Wang, Yongtao Sun, Song Zhai, Yan Zhuang, Shuguang Zhao, Whenzhen Kang, Xinhong Li, Dedong Huang, Xu G. Yu, Bruce D. Walker, and Marcus A. Altfeld. Identification of HLA-A11-Restricted HIV-1-Specific Cytotoxic T-Lymphocyte Epitopes in China. Curr. HIV Res., 5(1):119-128, Jan 2007. PubMed ID: 17266563. Show all entries for this paper.


Displaying record number 55718

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HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location Gag
Epitope AEWDRLHPV Epitope Alignment
AEWDRLHPV epitope logo
Epitope Name AV9-B40
Subtype B, F
Species (MHC/HLA) human(B40)
Immunogen HIV-1 infection
Country Argentina
Experimental methods  
Keywords dynamics, HLA associated polymorphism

Notes

References

Dilernia2008 Dario Alberto Dilernia, Leandro Jones, Sabrina Rodriguez, Gabriela Turk, Andrea E Rubio, Sandra Pampuro, Manuel Gomez-Carrillo, Christian Bautista, Gabriel Deluchi, Jorge Benetucci, María Beatriz Lasala, Leonardo Lourtau, Marcelo Horacio Losso, Héctor Perez, Pedro Cahn, and Horacio Salomón. HLA-Driven Convergence of HIV-1 Viral Subtypes B and F Toward the Adaptation to Immune Responses in Human Populations. PLoS ONE, 3(10):e3429, 2008. PubMed ID: 18941505. Show all entries for this paper.


Displaying record number 58493

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HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location Gag(210-218)
Epitope AEWDRLHPV Epitope Alignment
AEWDRLHPV epitope logo
Subtype B
Species (MHC/HLA) human(B*40:02)
Immunogen HIV-1 infection
Country Canada
Experimental methods Other
Keywords characterizing CD8+ T cells, elite controllers

Notes

References

Peretz2011 Yoav Peretz, Olivia Marra, Réjean Thomas, Danielle Legault, Pierre Côté, Mohamed-Rachid Boulassel, Danielle Rouleau, Jean-Pierre Routy, Rafick-Pierre Sékaly, Christos M Tsoukas, Cécile Tremblay, and Nicole F. Bernard. Relative Contribution of HIV-Specific Functional Lymphocyte Subsets Restricted by Protective and Non-Protective HLA Alleles. Viral Immunol, 24(3):189-198, Jun 2011. PubMed ID: 21668360. Show all entries for this paper.


Displaying record number 61534

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HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(78-86)
Epitope AEWDRLHPV Epitope Alignment
AEWDRLHPV epitope logo
Show epitope variants
Epitope Name Gag AV9
Subtype B
Species (MHC/HLA) human(B*40:02)
Immunogen HIV-1 infection
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining
Keywords subtype comparisons, variant cross-reactivity, optimal epitope, novel epitope, chronic infection

Notes

References

Watanabe2013 Koji Watanabe, Hayato Murakoshi, Yoshiko Tamura, Madoka Koyanagi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Identification of Cross-Clade CTL Epitopes in HIV-1 Clade A/E-Infected Individuals by Using the Clade B Overlapping Peptides. Microbes Infect., 15(13):874-886, Nov 2013. PubMed ID: 23968885. Show all entries for this paper.


Displaying record number 53894

Download this epitope record as JSON.

HXB2 Location Gag(210-218)
p24(78-86)
DNA(1417..1443)
Gag Epitope Map
Author Location p24(78-86)
Epitope AEWDRLHPV Epitope Alignment
AEWDRLHPV epitope logo
Subtype C
Species (MHC/HLA) human(B*40:06)
Immunogen HIV-1 infection
Country India
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, computational epitope prediction, immunodominance

Notes

References

Thakar2005 Madhuri R. Thakar, Leena S. Bhonge, Samir K. Lakhashe, U. Shankarkumar, Suvarna S. Sane, Smita S. Kulkarni, Bharati A. Mahajan, and Ramesh S. Paranjape. Cytolytic T Lymphocytes (CTLs) from HIV-1 Subtype C-Infected Indian Patients Recognize CTL Epitopes From a Conserved Immunodominant Region of HIV-1 Gag and Nef. J. Infect. Dis., 192(5):749-759, 1 Sep 2005. PubMed ID: 16088824. Show all entries for this paper.


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