HIV molecular immunology database
Found 19 matching records:
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(31-39) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Epitope Name | AY9 | |
Species (MHC/HLA) | human(B*15:17) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(31-39) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Epitope Name | AY9 | |
Species (MHC/HLA) | human(B*15:40) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(31-39) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Epitope Name | AY9 | |
Species (MHC/HLA) | human(B*18) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | ||
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Epitope Name | AY9 | |
Species (MHC/HLA) | human(B*18:01) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(31-39 HIV-MN) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | AY9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*18:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03 | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | escape, mutation acquisition, optimal epitope |
Liu2006 Yi Liu, John McNevin, Jianhong Cao, Hong Zhao, Indira Genowati, Kim Wong, Sherry McLaughlin, Matthew D. McSweyn, Kurt Diem, Claire E. Stevens, Janine Maenza, Hongxia He, David C. Nickle, Daniel Shriner, Sarah E. Holte, Ann C. Collier, Lawrence Corey, M. Juliana McElrath, and James I. Mullins. Selection on the Human Immunodeficiency Virus Type 1 Proteome following Primary Infection. J. Virol., 80(19):9519-9529, Oct 2006. PubMed ID: 16973556. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(31-39) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | AY9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*18:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | escape, acute/early infection |
Liu2011a Yi Liu, John P. McNevin, Sarah Holte, M. Juliana McElrath, and James I. Mullins. Dynamics of Viral Evolution and CTL Responses in HIV-1 Infection. PLoS One, 6(1):e15639, 2011. PubMed ID: 21283794. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(31-39) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Show epitope variants | ||
Subtype | B | |
Species (MHC/HLA) | human(B*18:01) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | PIC1362: A*02:01, A*25:01, B*18:01, B*51:01, C*01:02, C*12:03 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | viral fitness and reversion |
Liu2007a Yi Liu, John McNevin, Hong Zhao, Denis M. Tebit, Ryan M. Troyer, Matthew McSweyn, Ananta K. Ghosh, Daniel Shriner, Eric J. Arts, M. Juliana McElrath, and James I. Mullins. Evolution of Human Immunodeficiency Virus Type 1 Cytotoxic T-Lymphocyte Epitopes: Fitness-Balanced Escape. J. Virol., 81(22):12179-12188, Nov 2007. PubMed ID: 17728222. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | ||
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Epitope Name | AY9 | |
Species (MHC/HLA) | human(B*44) | |
Immunogen | ||
Experimental methods | ||
Keywords | optimal epitope, A-list |
Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(30-38) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Species (MHC/HLA) | human(B*44) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | rate of progression, acute/early infection |
Day2001 C. L. Day, A. K. Shea, M. A. Altfeld, D. P. Olson, S. P. Buchbinder, F. M. Hecht, E. S. Rosenberg, B. D. Walker, and S. A. Kalams. Relative dominance of epitope-specific cytotoxic T-lymphocyte responses in human immunodeficiency virus type 1-infected persons with shared HLA alleles. J. Virol., 75(14):6279-91, Jul 2001. URL: http://jvi.asm.org/cgi/content/full/75/14/6279. PubMed ID: 11413294. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp160(30-39 WEAU) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Show epitope variants | ||
Species (MHC/HLA) | human(B44) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | immunodominance, escape |
Borrow1997 P. Borrow, H. Lewicki, X. Wei, M. S. Horwitz, N. Peffer, H. Meyers, J. A. Nelson, J. E. Gairin, B. H. Hahn, M. B. Oldstone, and G. M. Shaw. Anti-Viral Pressure Exerted by HIV-1-Specific Cytotoxic T Lymphocytes (CTLs) During Primary Infection Demonstrated by Rapid Selection of CTL Escape Virus. Nat. Med., 3:205-211, 1997. Genetic pathways of virus escape from CTL pressure resembled virus escape from antiretroviral therapy. PubMed ID: 9018240. Show all entries for this paper.
Borrow1998 P. Borrow and G. M. Shaw. Cytotoxic T-Lymphocyte Escape Viral Variants: How Important Are They in Viral Evasion of Immune Clearance In Vivo? Immunol. Rev., 164:37-51, 1998. PubMed ID: 9795762. Show all entries for this paper.
Goulder1997e P. Goulder, D. Price, M. Nowak, S. Rowland-Jones, R. Phillips, and A. McMichael. Co-Evolution of Human Immunodeficiency Virus and Cytotoxic T-Lymphocyte Responses. Immunol. Rev., 159:17-29, 1997. PubMed ID: 9416500. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120(30-38 SF2) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Species (MHC/HLA) | human(B44) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | HAART, ART, acute/early infection |
Altfeld2001b M. Altfeld, E. S. Rosenberg, R. Shankarappa, J. S. Mukherjee, F. M. Hecht, R. L. Eldridge, M. M. Addo, S. H. Poon, M. N. Phillips, G. K. Robbins, P. E. Sax, S. Boswell, J. O. Kahn, C. Brander, P. J. Goulder, J. A. Levy, J. I. Mullins, and B. D. Walker. Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection. J. Exp. Med., 193(2):169-80, 15 Jan 2001. URL: http://www.jem.org/cgi/content/full/193/2/169. PubMed ID: 11148221. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120 | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Species (MHC/HLA) | human(B44) | |
Immunogen | HIV-1 infection | |
Experimental methods | ||
Keywords | epitope processing |
Cao2002 Huyen Cao, Deepak Agrawal, Nicholas Kushner, Neal Touzjian, Max Essex, and Yichen Lu. Delivery of exogenous protein antigens to major histocompatibility complex class I pathway in cytosol. J. Infect. Dis., 185(2):244-251, 15 Jan 2002. PubMed ID: 11807699. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | ( B consensus) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Epitope Name | AY9 | |
Subtype | B | |
Species (MHC/HLA) | human(B44) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A11, A29, B44, B8, Cw4, Cw7 | |
Country | United States | |
Experimental methods | Chromium-release assay, Cytokine production, Flow cytometric T-cell cytokine assay, Intracellular cytokine staining | |
Keywords | assay or method development, memory cells, characterizing CD8+ T cells |
Lichterfeld2004b Mathias Lichterfeld, Xu G. Yu, Michael T. Waring, Stanley K. Mui, Mary N. Johnston, Daniel Cohen, Marylyn M. Addo, John Zaunders, Galit Alter, Eunice Pae, Daryld Strick, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, and Marcus Altfeld. HIV-1-Specific Cytotoxicity Is Preferentially Mediated by a Subset of CD8+ T Cells Producing both Interferon-gamma and Tumor Necrosis Factor-alpha. Blood, 104(2):487-394, 15 Jul 2004. PubMed ID: 15059848. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | ||
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Species (MHC/HLA) | human(B44) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding | |
Keywords | binding affinity, immunodominance, optimal epitope |
Bihl2006 Florian Bihl, Nicole Frahm, Loriana Di Giammarino, John Sidney, Mina John, Karina Yusim, Tonia Woodberry, Kaori Sango, Hannah S. Hewitt, Leah Henry, Caitlyn H. Linde, John V. Chisholm, III, Tauheed M. Zaman, Eunice Pae, Simon Mallal, Bruce D Walker, Alessandro Sette, Bette T. Korber, David Heckerman, and Christian Brander. Impact of HLA-B Alleles, Epitope Binding Affinity, Functional Avidity, and Viral Coinfection on the Immunodominance of Virus-Specific CTL Responses. J. Immunol., 176(7):4094-4101, 1 Apr 2006. PubMed ID: 16547245. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp120 | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Epitope Name | AY9(gp120) | |
Subtype | B | |
Species (MHC/HLA) | human(B44) | |
Immunogen | HIV-1 infection | |
Country | China | |
Experimental methods | CD8 T-cell Elispot - IFNγ | |
Keywords | chronic infection |
Zhai2008 Song Zhai, Yan Zhuang, Yang Song, Shu Li, Dedong Huang, Wenzhen Kang, Xinhong Li, Qi Liao, Yanhou Liu, Zhongfang Zhao, Yichen Lu, and Yongtao Sun. HIV-1-Specific Cytotoxic T Lymphocyte (CTL) Responses Against Immunodominant Optimal Epitopes Slow the Progression of AIDS in China. Curr. HIV Res., 6(4):335-350, Jun 2008. PubMed ID: 18691032. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp160 | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | AY9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*44:03) | |
Immunogen | HIV-1 infection | |
Country | United States | |
Experimental methods | Chromium-release assay | |
Keywords | escape, acute/early infection |
Fischer2010 Will Fischer, Vitaly V. Ganusov, Elena E. Giorgi, Peter T. Hraber, Brandon F. Keele, Thomas Leitner, Cliff S. Han, Cheryl D. Gleasner, Lance Green, Chien-Chi Lo, Ambarish Nag, Timothy C. Wallstrom, Shuyi Wang, Andrew J. McMichael, Barton F. Haynes, Beatrice H. Hahn, Alan S. Perelson, Persephone Borrow, George M. Shaw, Tanmoy Bhattacharya, and Bette T. Korber. Transmission of Single HIV-1 Genomes and Dynamics of Early Immune Escape Revealed by Ultra-Deep Sequencing. PLoS One, 5(8):e12303, 2010. PubMed ID: 20808830. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp160(30-38 WEAU) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Show epitope variants | ||
Epitope Name | gp160 AY9 | |
Subtype | B | |
Species (MHC/HLA) | human(B*44:03) | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | WEAU: A01, A29, B08, B44 | |
Country | United States | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Chromium-release assay | |
Keywords | dynamics, immunodominance, escape, acute/early infection, kinetics, autologous responses, optimal epitope |
Jones2004 Nicola A. Jones, Xiping Wei, Darren R. Flower, MaiLee Wong, Franziska Michor, Michael S. Saag, Beatrice H. Hahn, Martin A. Nowak, George M. Shaw, and Persephone Borrow. Determinants of Human Immunodeficiency Virus Type 1 Escape from the Primary CD8+ Cytotoxic T Lymphocyte Response. J. Exp. Med., 200(10):1243-1256, 15 Nov 2004. PubMed ID: 15545352. Show all entries for this paper.
Yang2019 Yiding Yang, and Vitaly V. Ganusov. Defining Kinetic Properties of HIV-Specific CD8(+) T-Cell Responses in Acute Infection. Microorganisms, 7(3):microorganisms7030069 doi, Mar 2019. PubMed ID: 30836625 Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | Env(31-39) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Epitope Name | AY9 | |
Species (MHC/HLA) | human(C*02) | |
Immunogen | HIV-1 infection | |
Experimental methods | CD8 T-cell Elispot - IFNγ, Flow cytometric T-cell cytokine assay | |
Keywords | rate of progression, optimal epitope, chronic infection |
Pereyra2014 Florencia Pereyra, David Heckerman, Jonathan M. Carlson, Carl Kadie, Damien Z. Soghoian, Daniel Karel, Ariel Goldenthal, Oliver B. Davis, Charles E. DeZiel, Tienho Lin, Jian Peng, Alicja Piechocka, Mary Carrington, and Bruce D. Walker. HIV Control Is Mediated in Part by CD8+ T-Cell Targeting of Specific Epitopes. J. Virol., 88(22):12937-12948, Nov 2014. PubMed ID: 25165115. Show all entries for this paper.
Download this epitope record as JSON.
HXB2 Location | gp160(31-39) gp120(31-39) DNA(6315..6341) |
gp160 Epitope Map |
---|---|---|
Author Location | gp160(31-39) | |
Epitope |
AENLWVTVY
|
Epitope Alignment
|
Species (MHC/HLA) | human | |
Immunogen | HIV-1 infection | |
Patient MHC/HLA | A1, A29, B44, B8 | |
Experimental methods | CD8 T-cell Elispot - IFNγ, HLA binding | |
Keywords | HAART, ART, escape, viral fitness and reversion |
Asquith2006 Becca Asquith, Charles T. T. Edwards, Marc Lipsitch, and Angela R. McLean. Inefficient Cytotoxic T Lymphocyte-Mediated Killing of HIV-1-Infected Cells In Vivo. PLoS Biol., 4(4):e90, Apr 2006. PubMed ID: 16515366. Show all entries for this paper.