Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 62904

Download this epitope record as JSON.

HXB2 Location	Gag(167-175) p24(35-43)	Gag Epitope Map
Author Location	( SF)
Epitope	EVIPMFSAL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	(A*26:01)
Immunogen	peptide-HLA interaction
Country	Japan
Experimental methods	HLA binding
Keywords	binding affinity, HLA cross-presentation, HLA associated polymorphism

Notes

• Nonamer binding to HLA-A*26 (A*26:01, A*26:02, A*26:03) was studied and previously studied epitope EVIPMFSAL found to be the best binder to all three alleles of A*26. Anchor positions were found at 2 and 9. Position 1 was also found to be important for peptide binding.
• Other nonamers that bind A*26:01 are TLQEQIGWM and EPTGIRYQY.

References

Yamada1999a N. Yamada, Y. Ishikawa, T. Dumrese, K. Tokunaga, T. Juji, T. Nagatani, K. Miwa, H. G. Rammensee, and M. Takiguchi. Role of anchor residues in peptide binding to three HLA-A26 molecules. Tissue Antigens, 54(4):325-32 doi, Oct 1999. PubMed ID: 10551415 Show all entries for this paper.

Displaying record number 62905

Download this epitope record as JSON.

HXB2 Location	Gag(167-175) p24(35-43)	Gag Epitope Map
Author Location	( SF)
Epitope	EVIPMFSAL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	(A*26:02)
Immunogen	peptide-HLA interaction
Country	Japan
Experimental methods	HLA binding
Keywords	binding affinity, HLA cross-presentation, HLA associated polymorphism

Notes

• Nonamer binding to HLA-A*26 (A*26:01, A*26:02, A*26:03) was studied and previously studied epitope EVIPMFSAL found to be the best binder to all three alleles of A*26. Anchor positions were found at 2 and 9. Position 1 was also found to be important for peptide binding.
• Other nonamers that bind A*26:02 are AFSPEVIPM, ATPQDLNTM, DIAGTTSTL, TLQEQIGWM and EPTGIRYQY.

References

Yamada1999a N. Yamada, Y. Ishikawa, T. Dumrese, K. Tokunaga, T. Juji, T. Nagatani, K. Miwa, H. G. Rammensee, and M. Takiguchi. Role of anchor residues in peptide binding to three HLA-A26 molecules. Tissue Antigens, 54(4):325-32 doi, Oct 1999. PubMed ID: 10551415 Show all entries for this paper.

Displaying record number 62906

Download this epitope record as JSON.

HXB2 Location	Gag(167-175) p24(35-43)	Gag Epitope Map
Author Location	( SF)
Epitope	EVIPMFSAL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	(A*26:03)
Immunogen	peptide-HLA interaction
Country	Japan
Experimental methods	HLA binding
Keywords	binding affinity, HLA cross-presentation, HLA associated polymorphism

Notes

• Nonamer binding to HLA-A*26 (A*26:01, A*26:02, A*26:03) was studied and previously studied epitope EVIPMFSAL found to be the best binder to all three alleles of A*26. Anchor positions were found at 2 and 9. Position 1 was also found to be important for peptide binding.
• Other nonamers that bind A*26:03 are TLQEQIGWM and EPTGIRYQY.

References

Yamada1999a N. Yamada, Y. Ishikawa, T. Dumrese, K. Tokunaga, T. Juji, T. Nagatani, K. Miwa, H. G. Rammensee, and M. Takiguchi. Role of anchor residues in peptide binding to three HLA-A26 molecules. Tissue Antigens, 54(4):325-32 doi, Oct 1999. PubMed ID: 10551415 Show all entries for this paper.