HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 1 matching record:

Displaying record number 61523

Download this epitope record as JSON.

HXB2 Location Pol(283-290)
RT(128-135)
DNA(2931..2954)
Pol Epitope Map
Author Location Pol(283-290)
Epitope TAFTIPSI Epitope Alignment
TAFTIPSI epitope logo
Show epitope variants
Epitope Name Pol283-8, TI8
Subtype B
Species (MHC/HLA) human(B*51:01, B*52:01)
Immunogen HIV-1 infection
Patient MHC/HLA KI-071: A*24:02, A*31:01, B*40:06, B*52:01; KI-069: A*24:02, B*40:06, B*52:01, C*03:04, C*12:02; KI-130: A*24:02, B*07:02, B*52:01, C*07:02, C*12:02; KI-108: A*24:02, B*52:01, C*12:02; KI-090: A*24:02, B*52:01, B*55:01; KI-076: A*02:01, A*24:01, B*40:01, B*52:01; KI-037: A*24:02, B*40:02, B*52:01; KI-106: A*24:02, A*33:03, B*07:01, B*52:01; KI-167: A*24:02, B*52:01, B*54:01; KI-114: A*02:01, A*24:01, B*27:04, B*52:01; KI-056: A*24:02, B*40:02, B*52:01; KI-028: A*24:02, A*26:01, B*48:01, B*52:01
Country Australia, Canada, Japan, United States
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Other, Relative replication capacity assay, Tetramer binding
Keywords escape, HLA cross-presentation, structure, chronic infection

Notes

References

Yagita2013 Yuichi Yagita, Nozomi Kuse, Kimiko Kuroki, Hiroyuki Gatanaga, Jonathan M. Carlson, Takayuki Chikata, Zabrina L. Brumme, Hayato Murakoshi, Tomohiro Akahoshi, Nico Pfeifer, Simon Mallal, Mina John, Toyoyuki Ose, Haruki Matsubara, Ryo Kanda, Yuko Fukunaga, Kazutaka Honda, Yuka Kawashima, Yasuo Ariumi, Shinichi Oka, Katsumi Maenaka, and Masafumi Takiguchi. Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity. J. Virol., 87(4):2253-2263, Feb 2013. PubMed ID: 23236061. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health