Search CTL/CD8+ T-Cell Epitope Database

Found 41 matching records:

Displaying record number 59319

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HXB2 Location	Gag(9-23) p17(9-23) DNA(814..858)	Gag Epitope Map
Author Location	p17
Epitope	SGGKLDAWEKIRLRP	Epitope Alignment
Epitope Name	Gag 3
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide SGGKLDAWEKIRLRP was recognized by 2/44 (4%) infected patients in South Africa and 1/57 (2%)patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59330

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HXB2 Location	Gag(17-31) p17(17-31) DNA(838..882)	Gag Epitope Map
Author Location	p17
Epitope	EKIRLRPGGKKKYRL	Epitope Alignment
Epitope Name	Gag 5
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide EKIRLRPGGKKKYRL was recognized by 0/44 infected patients in South Africa and 14/57 (24%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59331

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HXB2 Location	Gag(29-43) p17(29-43) DNA(874..918)	Gag Epitope Map
Author Location	p17
Epitope	YRLKHLVWASRELER	Epitope Alignment
Epitope Name	Gag 8
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide YRLKHLVWASRELER was recognized by 2/44 (4%)infected patients in South Africa and 1/57(2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59332

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HXB2 Location	Gag(41-54) p17(41-54) DNA(910..951)	Gag Epitope Map
Author Location	p17
Epitope	LERFALNPGLLETS	Epitope Alignment
Epitope Name	Gag 11
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide LERFALNPGLLETS was recognized by 2/44 (4%) infected patients in South Africa and 7/57 (12%)patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59333

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HXB2 Location	Gag(78-92) p17(78-92) DNA(1021..1065)	Gag Epitope Map
Author Location	p17
Epitope	LYNTVATLYCVHQRI	Epitope Alignment
Epitope Name	Gag 21
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide LYNTVATLYCVHQRI was recognized by 5/44 (12%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59334

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HXB2 Location	Gag(140-154) p24(8-22) DNA(1207..1251)	Gag Epitope Map
Author Location	p24
Epitope	GQMVHQAISPRTLNA	Epitope Alignment
Epitope Name	Gag 38
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide GQMVHQAISPRTLNA was recognized by 5/44 (12%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59335

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HXB2 Location	Gag(144-158) p24(12-26) DNA(1219..1263)	Gag Epitope Map
Author Location	p24
Epitope	HQAISPRTLNAWVKV	Epitope Alignment
Epitope Name	Gag 39
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide HQAISPRTLNAWVKV was recognized by 4/44 (8%) infected patients in South Africa and 6/57 (10%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59336

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HXB2 Location	Gag(156-170) p24(24-38) DNA(1255..1299)	Gag Epitope Map
Author Location	p24
Epitope	VKVIEEKAFSPEVIP	Epitope Alignment
Epitope Name	Gag 42
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide VKVIEEKAFSPEVIP was recognized by 5/44 (12%) infected patients in South Africa and 3/57 (5%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59337

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HXB2 Location	Gag(160-174) p24(28-42) DNA(1267..1311)	Gag Epitope Map
Author Location	p24
Epitope	EEKAFSPEVIPMFSA	Epitope Alignment
Epitope Name	Gag 43
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide EEKAFSPEVIPMFSA was recognized by 5/44 (12%) infected patients in South Africa and 6/57 (10%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59338

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HXB2 Location	Gag(176-190) p24(44-58) DNA(1315..1359)	Gag Epitope Map
Author Location	p24
Epitope	SEGATPQDLNTMLNT	Epitope Alignment
Epitope Name	Gag 47
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide SEGATPQDLNTMLNT was recognized by 8/44 (19%) infected patients in South Africa and 3/57 (5%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59339

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HXB2 Location	Gag(180-194) p24(48-62) DNA(1327..1371)	Gag Epitope Map
Author Location	p24
Epitope	TPQDLNTMLNTVGGH	Epitope Alignment
Epitope Name	Gag 48
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide TPQDLNTMLNTVGGH was recognized by 12/44 (27%) infected patients in South Africa and 7/57 (12%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59340

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HXB2 Location	Gag(184-198) p24(52-66) DNA(1339..1383)	Gag Epitope Map
Author Location	p24
Epitope	LNTMLNTGVGHQAAM	Epitope Alignment
Epitope Name	Gag 49
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide LNTMLNTGVGHQAAM was recognized by 2/44 (4%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59341

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HXB2 Location	Gag(192-206) p24(60-74) DNA(1363..1407)	Gag Epitope Map
Author Location	p24
Epitope	GGHQAAMQMLKDTIN	Epitope Alignment
Epitope Name	Gag 51
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide GGHQAAMQMLKDTIN was recognized by 4/44 (8%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59342

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HXB2 Location	Gag(196-210) p24(64-78) DNA(1375..1419)	Gag Epitope Map
Author Location	p24
Epitope	AAMQMLKDTINEEAA	Epitope Alignment
Epitope Name	Gag 52
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide AAMQMLKDTINEEAA was recognized by 2/44 (4%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59343

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HXB2 Location	Gag(200-214) p24(68-82) DNA(1387..1431)	Gag Epitope Map
Author Location	p24
Epitope	MLKDTINEEAAEWDR	Epitope Alignment
Epitope Name	Gag 53
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide MLKDTINEEAAEWDR was recognized by 4/44 (8%) infected patients in South Africa and 7/57 (12%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59344

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HXB2 Location	Gag(204-218) p24(72-86) DNA(1399..1443)	Gag Epitope Map
Author Location	p24
Epitope	TINEEAAEWDRLHPV	Epitope Alignment
Epitope Name	Gag 54
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide TINEEAAEWDRLHPV was recognized by 2/44 (4%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59345

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HXB2 Location	Gag(238-252) p24(106-120) DNA(1501..1545)	Gag Epitope Map
Author Location	p24
Epitope	GTTSTLQEQIAWMTS	Epitope Alignment
Epitope Name	Gag 63
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide GTTSTLQEQIAWMTS was recognized by 5/44 (12%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59346

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HXB2 Location	Gag(253-267) p24(121-135) DNA(1546..1590)	Gag Epitope Map
Author Location	p24
Epitope	NPPIPVGEIYKRWII	Epitope Alignment
Epitope Name	Gag 67
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide NPPIPVGEIYKRWII was recognized by 2/44 (4%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59347

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HXB2 Location	Gag(257-271) p24(125-139) DNA(1558..1602)	Gag Epitope Map
Author Location	p24
Epitope	PVGEIYKRWIILGLN	Epitope Alignment
Epitope Name	Gag 68
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide PVGEIYKRWIILGLN was recognized by 2/44 (4%) infected patients in South Africa and 6/57 (10%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59348

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HXB2 Location	Gag(269-283) p24(137-151) DNA(1594..1638)	Gag Epitope Map
Author Location	p24
Epitope	GLNKIVRMYSPVSIL	Epitope Alignment
Epitope Name	Gag 71
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide GLNKIVRMYSPVSIL was recognized by 2/44 (4%) infected patients in South Africa and 3/57 (5%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59349

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HXB2 Location	Gag(277-290) p24(145-158) DNA(1618..1659)	Gag Epitope Map
Author Location	p24
Epitope	YSPVSILDIRQGPK	Epitope Alignment
Epitope Name	Gag 73
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide YSPVSILDIRQGPK was recognized by 2/44 (4%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59350

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HXB2 Location	Gag(290-304) p24(158-172) DNA(1657..1701)	Gag Epitope Map
Author Location	p24
Epitope	KEPFRDYVDRFFKTL	Epitope Alignment
Epitope Name	Gag 77
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide KEPFRDYVDRFFKTL was recognized by 4/44 (8%) infected patients in South Africa and 11/57 (20%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59351

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HXB2 Location	Gag(294-308) p24(162-176) DNA(1669..1713)	Gag Epitope Map
Author Location	p24
Epitope	RDYVDRFFKTLRAEQ	Epitope Alignment
Epitope Name	Gag 78
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide RDYVDRFFKTLRAEQ was recognized by 7/44 (15%) infected patients in South Africa and 6/57 (10%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59352

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HXB2 Location	Gag(298-311) p24(166-179) DNA(1681..1722)	Gag Epitope Map
Author Location	p24
Epitope	DRFFKTLRAEQATQ	Epitope Alignment
Epitope Name	Gag 79
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide DRFFKTLRAEQATQ was recognized by 4/44 (8%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59353

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HXB2 Location	Gag(301-315) p24(169-183) DNA(1690..1734)	Gag Epitope Map
Author Location	p24
Epitope	FKTLRAEQATQDVKN	Epitope Alignment
Epitope Name	Gag 80
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide FKTLRAEQATQDVKN was recognized by 2/44 (4%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59354

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HXB2 Location	Gag(305-318) p24(173-186) DNA(1702..1743)	Gag Epitope Map
Author Location	p24
Epitope	RAEQATQDVKNWMT	Epitope Alignment
Epitope Name	Gag 81
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide RAEQATQDVKNWMT was recognized by 2/44 (4%) infected patients in South Africa and 10/57 (17%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59355

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HXB2 Location	Gag(330-343) p24(198-211) DNA(1777..1818)	Gag Epitope Map
Author Location	p24
Epitope	CKTILKALGPGATL	Epitope Alignment
Epitope Name	Gag 88
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide CKTILKALGPGATL was recognized by 2/44 (4%) infected patients in South Africa and 4/57 (7%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59356

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HXB2 Location	Gag(429-443) p2p7p1p6(66-80) DNA(2074..2118)	Gag Epitope Map
Author Location	p2p7p1p6
Epitope	RQANFLGKIWPSNKG	Epitope Alignment
Epitope Name	Gag 115
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide RQANFLGKIWPSNKG was recognized by 5/44 (12%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59357

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HXB2 Location	Gag(433-447) p2p7p1p6(70-84) DNA(2086..2130)	Gag Epitope Map
Author Location	p2p7p1p6
Epitope	FLGKIWPSNKGRPGN	Epitope Alignment
Epitope Name	Gag 116
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide FLGKIWPSNKGRPGN was recognized by 2/44 (4%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59358

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HXB2 Location	Nef(9-23) DNA(8821..8865)	Nef Epitope Map
Author Location	Nef
Epitope	SIVGWPAVRERIRRT	Epitope Alignment
Epitope Name	Nef 3
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide SIVGWPAVRERIRRT was recognized by 3/44 (6%) infected patients in South Africa and 4/57 (7%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59359

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HXB2 Location	Nef(67-81) DNA(8995..9039)	Nef Epitope Map
Author Location	Nef
Epitope	GFPVRPQVPLRPMTY	Epitope Alignment
Epitope Name	Nef 18
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide GFPVRPQVPLRPMTY was recognized by 13/44 (29%) infected patients in South Africa and 14/57 (24%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59360

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HXB2 Location	Nef(71-85) DNA(9007..9051)	Nef Epitope Map
Author Location	Nef
Epitope	RPQVPLRPMTYKAAL	Epitope Alignment
Epitope Name	Nef 19
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide RPQVPLRPMTYKAAL was recognized by 11/44 (24%) infected patients in South Africa and 18/57 (32%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

---

Displaying record number 59361

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HXB2 Location	Nef(90-104) DNA(9064..9108)	Nef Epitope Map
Author Location	Nef
Epitope	FLKEKGGLEGLIYSK	Epitope Alignment
Epitope Name	Nef 24
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide FLKEKGGLEGLIYSK was recognized by 3/44 (6%) infected patients in South Africa and 7/57 (12%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59362

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HXB2 Location	Nef(100-114) DNA(9094..9138)	Nef Epitope Map
Author Location	Nef
Epitope	LIYSKKRQEILDLWV	Epitope Alignment
Epitope Name	Nef 27
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide LIYSKKRQEILDLWV was recognized by 5/44 (12%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59363

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HXB2 Location	Nef(104-118) DNA(9106..9150)	Nef Epitope Map
Author Location	Nef
Epitope	KKRQEILDLWVYHTQ	Epitope Alignment
Epitope Name	Nef 28
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide KKRQEILDLWVYHTQ was recognized by 13/44 (29%) infected patients in South Africa and 11/57 (20%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59364

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HXB2 Location	Nef(108-122) DNA(9118..9162)	Nef Epitope Map
Author Location	Nef
Epitope	EILDLWVYHTQGYFP	Epitope Alignment
Epitope Name	Nef 29
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide EILDLWVYHTQGYFP was recognized by 3/44 (6%) infected patients in South Africa and 3/57 (5%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59365

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HXB2 Location	Nef(112-126) DNA(9130..9174)	Nef Epitope Map
Author Location	Nef
Epitope	LWVYHTQGYFPDWQN	Epitope Alignment
Epitope Name	Nef 30
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide LWVYHTQGYFPDWQN was recognized by 5/44 (12%) infected patients in South Africa and 4/57 (7%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59366

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HXB2 Location	Nef(116-130) DNA(9142..9186)	Nef Epitope Map
Author Location	Nef
Epitope	HTQGYFPDWQNYTPG	Epitope Alignment
Epitope Name	Nef 31
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide HTQGYFPDWQNYTPG was recognized by 11/44 (24%) infected patients in South Africa and 7/57 (12%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59367

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HXB2 Location	Nef(124-138) DNA(9166..9210)	Nef Epitope Map
Author Location	Nef
Epitope	WQNYTPGPGIRYPLT	Epitope Alignment
Epitope Name	Nef 33
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide WQNYTPGPGIRYPLT was recognized by 8/44 (18%) infected patients in South Africa and 1/57 (2%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59368

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HXB2 Location	Nef(128-141) DNA(9178..9219)	Nef Epitope Map
Author Location	Nef
Epitope	TPGPGIRYPLTFGW	Epitope Alignment
Epitope Name	Nef 34
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide TPGPGIRYPLTFGW was recognized by 11/44 (24%) infected patients in South Africa and 9/57 (15%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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Displaying record number 59369

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HXB2 Location	Nef(131-145) DNA(9187..9231)	Nef Epitope Map
Author Location	Nef
Epitope	PGIRYPLTFGWCFKL	Epitope Alignment
Epitope Name	Nef 35
Subtype	multiple
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Country	Cameroon, South Africa
Experimental methods	CD8 T-cell Elispot - IFNγ
Keywords	subtype comparisons, immunodominance

Notes

• The study examined patients' reactivity to HIV consensus M Gag and Nef peptides. Patients in Cameroon infected by CRF02_AG and non-CRF02_AG were compared. Responses of patients from a multi-clade country, Cameroon, were compared with patients from a single-clade country, South Africa. No patterns of immunodominance could be detected in either comparison.
• Peptide PGIRYPLTFGWCFKL was recognized by 3/44 (6%) infected patients in South Africa and 19/57 (34%) patients in Cameroon.

References

Tongo2014 Marcel Tongo, Lycias Zembe, Eugenie Ebong, Surita Roux, Linda-Gail Bekker, Carolyn Williamson, Eitel Mpoudi-Ngole, and Wendy A. Burgers. Striking Lack of T Cell Immunodominance in both a Multiclade and Monoclade HIV-1 Epidemic: Implications for Vaccine Development. Vaccine, 32(20):2328-2336, 25 Apr 2014. PubMed ID: 24598726. Show all entries for this paper.

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