HIV molecular immunology database

 

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Displaying record number 761

HXB2 Location gp160(311-320)
gp120(311-320)
DNA(7155..7184)
gp160 Epitope Map
Author Location gp160(318-327 IIIB)
Epitope RGPGRAFVTI Epitope Alignment
RGPGRAFVTI epitope logo
Species (MHC/HLA) mouse(H-2Dd)
Immunogen peptide-HLA interaction
Experimental methods  
Keywords  

Notes

References

Takeshita1995 T. Takeshita, H. Takahashi, S. Kozlowski, J. D. Ahlers, C. D. Pendleton, R. L. Moore, Y. Nakagawa, K. Yokomuro, B. S. Fox, D. H. Margulies, and J. A. Berzofsky. Molecular Analysis of the Same HIV Peptide Functionally Binding to Both a Class I and a Class II MHC Molecule. J. Immunol., 154:1973-1986, 1995. Of RGPGRAFVTI, the upper case amino acids iGPgRaFvtI are critical for binding, consistent with H-2D$d$ motif XGPX(RKH)XXX(X)(LIF). Stimulation of the HLA class II I-A$^d$ required a longer peptide, IQRGPGRAFVTI or RIQRGPGRAFVTI, and riqrgPgRaFvti were essential for binding to the Class II molecule. PubMed ID: 7530749. Show all entries for this paper.


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