HIV molecular immunology database


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Displaying record number 863

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HXB2 Location gp160(770-780)
gp160 Epitope Map
Author Location gp41(768-778 NL43)
Epitope RLRDLLLIVTR Epitope Alignment
RLRDLLLIVTR epitope logo
Species (MHC/HLA) human(A*03:01)
Immunogen HIV-1 infection
Experimental methods  



Takahashi1991 K. Takahashi, L.-C. Dai, T. R. Fuerst, W. E. Biddison, P. L. Earl, B. Moss, and F. A. Ennis. Specific Lysis of Human Immunodeficiency Virus Type 1-Infected Cells by a HLA-A3.1-Restricted CD8+ Cytotoxic T-Lymphocyte Clone That Recognizes a Conserved Peptide Sequence within the gp41 Subunit of the Envelope Protein. Proc. Natl. Acad. Sci. U.S.A., 88:10277-10281, 1991. gp41 epitope: RLRDLLLIVTR, HLA A3.1 (NL43). Synthetic peptides of RF and CDC4 were recognized by CTL clone despite non-conservative Thr to (Val or Ala) change, but an MN peptide with four natural substitutions was not recognized. PubMed ID: 1719555. Show all entries for this paper.

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