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Displaying record number 758

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HXB2 Location	gp160(311-320) gp120(311-320) DNA(7155..7184)	gp160 Epitope Map
Author Location	gp160(318-327 IIIB)
Epitope	`RGPGRAFVTI`	Epitope Alignment
Epitope Name	R10I
Species (MHC/HLA)	mouse
Immunogen	vaccine
Experimental methods
Keywords	optimal epitope

Vaccine Details

Vaccine type	peptide
Vaccine strain	B clade IIIB
Vaccine component	Env V3

Notes

RGPGRAFVTI was defined as the optimal peptide for vaccination, out of RIQRGPGRAFVTIGK.
This peptide, in a carrier-free form in Freund's adjuvant, could stimulate Env specific CTL in BALB/c mice.

References

Nehete1995 P. N. Nehete, K. S. Casement, R. B. Arlinghus, and K. J. Sastry. Studies on In Vivo Induction of HIV-1 Envelope-Specific Cytotoxic T Lymphocytes by Synthetic Peptides from the V3 Loop Region of HIV-1 IIIB gp120. Cell. Immunol., 160:217-223, 1995. PubMed ID: 7720083. Show all entries for this paper.