HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 61518

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HXB2 Location Pol(62-69)
Protease(6-13)
DNA(2268..2291)
Pol Epitope Map
Author Location Pol(14-21)
Epitope WQRPLVTI Epitope Alignment
WQRPLVTI epitope logo
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Epitope Name WI8
Subtype B
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection
Patient MHC/HLA KI-698: A*02:01, A*24:02, B*51:01, B*52:01, C*12:02, C*15:02; KI-647: A*11:01, A*24:02, B*52:01, B*67:01, C*07:02, C*12:02; KI-740: A*24:02, B*07:02, B*52:01, C*07:02, C*12:02; KI-894: A*24:02, A*26:01, B*40:02, B*52:01, C*03:04, C*12:02; KI-906: A*02:06, A*11:01, B*15:01, B*52:01, C*04:01, C*12:02
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Relative replication capacity assay
Keywords escape, mutation acquisition, novel epitope, chronic infection

Notes

References

Murakoshi2017 Hayato Murakoshi, Madoka Koyanagi, Takayuki Chikata, Mohammad Arif Rahman, Nozomi Kuse, Keiko Sakai, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses. J. Virol., 91(4), 15 Feb 2017. PubMed ID: 27903797. Show all entries for this paper.


Displaying record number 61521

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HXB2 Location Pol(464-474)
RT(309-319)
DNA(3474..3506)
Pol Epitope Map
Author Location Pol
Epitope ILKEPVHGVYY Epitope Alignment
ILKEPVHGVYY epitope logo
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Epitope Name IY11
Subtype B
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Relative replication capacity assay
Keywords escape, mutation acquisition, novel epitope, chronic infection

Notes

References

Murakoshi2017 Hayato Murakoshi, Madoka Koyanagi, Takayuki Chikata, Mohammad Arif Rahman, Nozomi Kuse, Keiko Sakai, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses. J. Virol., 91(4), 15 Feb 2017. PubMed ID: 27903797. Show all entries for this paper.


Displaying record number 61519

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HXB2 Location Pol(928-935)
Integrase(213-220)
DNA(4866..4889)
Pol Epitope Map
Author Location Pol(111-119)
Epitope LQKQITKI Epitope Alignment
LQKQITKI epitope logo
Show epitope variants
Epitope Name LI8
Subtype B
Species (MHC/HLA) human(B*52:01)
Immunogen HIV-1 infection
Patient MHC/HLA KI-108: A*24:02, B*52:01, C*12:02
Country Japan
Experimental methods CD8 T-cell Elispot - IFNγ, Intracellular cytokine staining, Relative replication capacity assay
Keywords escape, mutation acquisition, novel epitope, chronic infection

Notes

References

Murakoshi2017 Hayato Murakoshi, Madoka Koyanagi, Takayuki Chikata, Mohammad Arif Rahman, Nozomi Kuse, Keiko Sakai, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi. Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses. J. Virol., 91(4), 15 Feb 2017. PubMed ID: 27903797. Show all entries for this paper.


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