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HXB2 Location	Gag(263-272) p24(131-140) DNA(1576..1605)	Gag Epitope Map
Author Location
Epitope	KRWIILGLNK	Epitope Alignment
Epitope Name	KK10
Species (MHC/HLA)	human, mouse(B27)
Immunogen	HIV-1 infection, peptide-HLA interaction
Experimental methods	Chromium-release assay, HLA binding, Tetramer binding
Keywords	review, epitope processing, escape, structure, assay or method development, optimal epitope

Notes

• This historical essay recounts the discovery of antigenic peptide processing by MHC-I. New techniques, the first epitope in HIV (KK10), epitope identification, escape mutations and HLA type are discussed with respect to CTLs in HIV infection control.

References

McMichael2007a Andrew J McMichael. From Influenza to HIV---and Back? Nat. Immunol., 8(11):1149-1151, Nov 2007. PubMed ID: 17952038. Show all entries for this paper.