HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 3 matching records:

Displaying record number 45

HXB2 Location Gag(24-32)
p17(24-32)
DNA(859..885)
Gag Epitope Map
Author Location p17(24-32)
Epitope GGKKKYKLK Epitope Alignment
GGKKKYKLK epitope logo
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Klenerman1995 P. Klenerman, U.-C. Meier, R. E. Phillips, and A. J. McMichael. The Effects of Natural Altered Peptide Ligands on the Whole Blood Cytotoxic T Lymphocyte Response to Human Immunodeficiency Virus. Eur. J. Immunol., 25:1927-1931, 1995. This paper explores naturally occurring altered peptide ligands and their ability to sustain CTL, serve as antagonists to CTL specific for other variants, and to allow cell killing. The authors propose that a CTL response may be sustained in vivo that fails to recognize viral variants as they arise, proposing a mechanism for T-cell original antigenic sin. PubMed ID: 7542596. Show all entries for this paper.


Displaying record number 276

HXB2 Location Gag(263-272)
p24(131-140)
DNA(1576..1605)
Gag Epitope Map
Author Location p24(263-272)
Epitope KRWIIMGLNK Epitope Alignment
KRWIIMGLNK epitope logo
Species (MHC/HLA) human(B27)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Klenerman1995 P. Klenerman, U.-C. Meier, R. E. Phillips, and A. J. McMichael. The Effects of Natural Altered Peptide Ligands on the Whole Blood Cytotoxic T Lymphocyte Response to Human Immunodeficiency Virus. Eur. J. Immunol., 25:1927-1931, 1995. This paper explores naturally occurring altered peptide ligands and their ability to sustain CTL, serve as antagonists to CTL specific for other variants, and to allow cell killing. The authors propose that a CTL response may be sustained in vivo that fails to recognize viral variants as they arise, proposing a mechanism for T-cell original antigenic sin. PubMed ID: 7542596. Show all entries for this paper.


Displaying record number 407

HXB2 Location Pol(173-181)
RT(18-26)
DNA(2601..2627)
Pol Epitope Map
Author Location RT(185-193 LAI)
Epitope GPKVKQWPL Epitope Alignment
GPKVKQWPL epitope logo
Subtype B
Species (MHC/HLA) human(B8)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Klenerman1995 P. Klenerman, U.-C. Meier, R. E. Phillips, and A. J. McMichael. The Effects of Natural Altered Peptide Ligands on the Whole Blood Cytotoxic T Lymphocyte Response to Human Immunodeficiency Virus. Eur. J. Immunol., 25:1927-1931, 1995. This paper explores naturally occurring altered peptide ligands and their ability to sustain CTL, serve as antagonists to CTL specific for other variants, and to allow cell killing. The authors propose that a CTL response may be sustained in vivo that fails to recognize viral variants as they arise, proposing a mechanism for T-cell original antigenic sin. PubMed ID: 7542596. Show all entries for this paper.

Menendez-Arias1998 L. Menendez-Arias, A. Mas, and E. Domingo. Cytotoxic T-Lymphocyte Responses to HIV-1 Reverse Transcriptase. Viral Immunol., 11:167-181, 1998. PubMed ID: 10189185. Show all entries for this paper.


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