Search CTL/CD8+ T-Cell Epitope Database

Found 12 matching records:

Displaying record number 1110

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HXB2 Location	Gag(18-26) p17(18-26) DNA(841..867)	Gag Epitope Map
Author Location	p17( subtype B)
Epitope	KIRLRPGGK	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A3)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11 of 16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8+ gamma-IFN responses in the cervix -- systemic CD8+ T-cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T-cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T-cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 1167

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HXB2 Location	Gag(77-85) p17(77-85) DNA(1018..1044)	Gag Epitope Map
Author Location	p17( subtype A)
Epitope	SLYNTVATL	Epitope Alignment
Subtype	A
Species (MHC/HLA)	human(A*02:01, A*02:14)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.
• The epitope variants SLYNTVATL and SLFNTVATL were both recognized.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 145

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HXB2 Location	Gag(147-155) p24(15-23) DNA(1228..1254)	Gag Epitope Map
Author Location	p24( subtype A)
Epitope	LSPRTLNAW	Epitope Alignment
Subtype	A
Species (MHC/HLA)	human(B57, B58)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 146

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HXB2 Location	Gag(148-156) p24(16-24) DNA(1231..1257)	Gag Epitope Map
Author Location	p24( subtype B)
Epitope	SPRTLNAWV	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*81:01, B7)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 198

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HXB2 Location	Gag(179-188) p24(47-56) DNA(1324..1353)	Gag Epitope Map
Author Location	p24( subtype A)
Epitope	ATPQDLNMML	Epitope Alignment
Subtype	A
Species (MHC/HLA)	human(B53)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T-cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T-cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T-cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 197

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HXB2 Location	Gag(183-191) p24(51-59) DNA(1336..1362)	Gag Epitope Map
Author Location	p24( subtype A)
Epitope	DLNMMLNIV	Epitope Alignment
Subtype	A
Species (MHC/HLA)	human(B14)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T-cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T-cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T-cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 399

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HXB2 Location	Pol(86-94) Protease(30-38) DNA(2340..2366)	Pol Epitope Map
Author Location	Pol( subtype A)
Epitope	DTVLEDINL	Epitope Alignment
Subtype	A
Species (MHC/HLA)	human(A*68:02)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 IFNγ responses in the cervix---systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 580

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HXB2 Location	Pol(811-819) Integrase(96-104) DNA(4515..4541)	Pol Epitope Map
Author Location	Pol( subtype A)
Epitope	ETAYFILKL	Epitope Alignment
Subtype	A
Species (MHC/HLA)	human(A*68:02)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 685

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HXB2 Location	gp160(208-217) gp120(208-217) DNA(6846..6875)	gp160 Epitope Map
Author Location	gp120( subtype B)
Epitope	VSFEPIPIHY	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A29)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 969

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HXB2 Location	Nef(74-81) DNA(9016..9039)	Nef Epitope Map
Author Location	Nef( subtype B)
Epitope	VPLRPMTY	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B35)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 1050

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HXB2 Location	Nef(128-137) DNA(9178..9207)	Nef Epitope Map
Author Location	Nef(128-137 subtype B)
Epitope	TPGPGVRYPL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*81:01, B7)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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Displaying record number 1068

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HXB2 Location	Nef(135-143) DNA(9199..9225)	Nef Epitope Map
Author Location	Nef( subtype D)
Epitope	YPLTFGWCF	Epitope Alignment
Subtype	D
Species (MHC/HLA)	human(B18)
Immunogen	HIV-1 exposed seronegative
Experimental methods
Keywords

Notes

• 11/16 heavily HIV exposed but persistently seronegative sex-workers in Nairobi had HIV-specific CD8 gamma-IFN responses in the cervix -- systemic CD8+ T cell responses tended to be to the same epitopes but at generally lower levels than cervical CD8+ T cell responses.
• Low risk individuals did not have such CD8+ cells.
• CD8+ T cell epitopes: DTVLEDINL (3 individuals), SLYNTVATL (4 individuals), LSPRTLNAW (3 individuals) and YPLTFGWCF (4 individuals) were most commonly recognized by the HIV-resistant women.

References

Kaul2000 R. Kaul, F. A. Plummer, J. Kimani, T. Dong, P. Kiama, T. Rostron, E. Njagi, K. S. MacDonald, J. J. Bwayo, A. J. McMichael, and S. L. Rowland-Jones. HIV-1-Specific Mucosal CD8+ Lymphocyte Responses in the Cervix of HIV-1-Resistant Prostitutes in Nairobi. J. Immunol., 164:1602-1611, 2000. PubMed ID: 10640781. Show all entries for this paper.

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