Search CTL/CD8+ T-Cell Epitope Database

Found 23 matching records:

Displaying record number 58784

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HXB2 Location	Gag(135-143) p24(3-11) DNA(1192..1218)	Gag Epitope Map
Author Location	p24(135-143)
Epitope	`VQNLQGQMV`	Epitope Alignment
Species (MHC/HLA)	human(B*13:02)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope VQNLQGQMV has residue Q at position P2, binding to HLA pocket B and residue LIV at the C-terminal, binding to HLA pocket F. Restricting HLA is B*1302 [Honeyborne et al. JVI 81:3667-3672 (2007)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58798

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HXB2 Location	Gag(140-150) p24(8-18) DNA(1207..1239)	Gag Epitope Map
Author Location	p24(140-150)
Epitope	`GQMVHQAISPR`	Epitope Alignment
Species (MHC/HLA)	human(A*74:01)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope GQMVHQAISPR has residue IQ at position P2, binding to HLA pocket B; and residue W at the C-terminal, binding to HLA pocket F. Restricting HLA is A*7401 [Matthews et al. JI 186:5675-5686 (2011)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58794

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HXB2 Location	Gag(147-155) p24(15-23) DNA(1228..1254)	Gag Epitope Map
Author Location	p24(147-155)
Epitope	`ISPRTLNAW`	Epitope Alignment
Species (MHC/HLA)	human(B*57:02)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope ISPRTLNAW has residue K at position P1, binding pocket A; ATS at position P2, binding to HLA pocket B; and residue FW at the C-terminal, binding to HLA pocket F. Restricting HLA is B*5702 [Goulder et al. ARHR 12:1691-1698 (1996)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61600

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HXB2 Location	Gag(162-170) p24(30-38) DNA(1273..1299)	Gag Epitope Map
Author Location	Gag(164-172)
Epitope	`KKFGAEVVP`	Epitope Alignment
Epitope Name	Gag164-172KP9
Species (MHC/HLA)	macaque(Mane A*10)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Gag epitope KKFGAEVVP is Mane A*10-restricted [Smith et al. JI 79:684-695(2005)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58795

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HXB2 Location	Gag(162-172) p24(30-40) DNA(1273..1305)	Gag Epitope Map
Author Location	p24(162-172)
Epitope	`KAFSPEVIPMF`	Epitope Alignment
Species (MHC/HLA)	human(B57:01, B57:03)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope KAFSPEVIPMF has residue K at position P1, binding pocket A; ATS at position P2, binding to HLA pocket B; and residue FW at the C-terminal, binding to HLA pocket F. Restricting HLA is B*5701/B*5703 [Goulder et al. ARHR 12:1691-1698 (1996)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61593

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HXB2 Location	Gag(179-187) p24(47-55) DNA(1324..1350)	Gag Epitope Map
Author Location	p24(181-189)
Epitope	`CTPYDINQM`	Epitope Alignment
Epitope Name	Gag181-189CM9
Species (MHC/HLA)	macaque(Mamu A*01)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV p24 Gag epitope CTPYDINQM has residue ST at position P2, residue P at position P3, binding to HLA pocket B; and residues FLIVM at the C-terminal, binding to HLA pocket F. Restricting HLA is Mamu A*01 [Allen et al. JVI 75:738-749 (2001)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58789

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HXB2 Location	Gag(180-188) p24(48-56) DNA(1327..1353)	Gag Epitope Map
Author Location	p24(180-189)
Epitope	`TPQDLNTML`	Epitope Alignment
Species (MHC/HLA)	human(B42:01, B81:01)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope TPQDLNTML has residue PI at position P2, binding to HLA pocket B; and residue LMIF at the C-terminal, binding to HLA pocket F. Restricting HLA is B*4201. When restricted by B*8101, it has P at position P2, binding pocket B; LMIF at the C-terminal, binding pocket F [Goulder et al. JVI 74:5679-5690 (2000)], [Leslie et al. JI 177:4699-4708 (2006)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58796

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HXB2 Location	Gag(203-212) p24(71-80) DNA(1396..1425)	Gag Epitope Map
Author Location	p24(203-212)
Epitope	`ETINEEAAAEW`	Epitope Alignment
Species (MHC/HLA)	human(A*25:01)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between dominant HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope ETINEEAAAEW has residue DE at position P1, binding pocket A; TVILF at position P2, binding to HLA pocket B; and residue W at the C-terminal, binding to HLA pocket F. Restricting HLA is A*2501 [Klenerman et al. AIDS 10:348-350 (1996)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61601

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HXB2 Location	Gag(204-214) p24(72-82) DNA(1399..1431)	Gag Epitope Map
Author Location	Gag(206-216)
Epitope	`IINEEAADWDL`	Epitope Alignment
Species (MHC/HLA)	macaque(Mamu-A1*043:01)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Gag epitope IINEEAADWDL is Mamu A1*043:01(90-120-Ia)-restricted [Nomura and Matano Front. Microbiol. 3:234(2012)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58793

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HXB2 Location	Gag(240-249) p24(108-117) DNA(1507..1536)	Gag Epitope Map
Author Location	p24(240-249)
Epitope	`TSTLQEQIAW`	Epitope Alignment
Species (MHC/HLA)	human(B57:01, B57:02, B57:03, B58:01)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope TSTLQEQIAW has residue K at position P1, binding pocket A; ATS at position P2, binding to HLA pocket B; and residue FW at the C-terminal, binding to HLA pocket F. Restricting HLA is B*5701/B*5702/B*5703/B*580 [Goulder et al. ARHR 12:1691-1698 (1996)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61602

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HXB2 Location	Gag(241-249) p24(109-117) DNA(1510..1536)	Gag Epitope Map
Author Location	Gag(241-249)
Epitope	`SSVDEQIQW`	Epitope Alignment
Species (MHC/HLA)	macaque(Mamu A1*065:01)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Gag epitope SSVDEQIQW is Mamu A1*065:01(90-120-Ia)-restricted [Nomura and Matano Front. Microbiol. 3:234(2012)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58786

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HXB2 Location	Gag(263-272) p24(131-140) DNA(1576..1605)	Gag Epitope Map
Author Location	p24(262-270)
Epitope	`KRWIILGLNK`	Epitope Alignment
Species (MHC/HLA)	human(B*27:05)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope KRWIILGLNK has residue RK at position P1, binding pocket A; R at position P2, binding to HLA pocket B; YFWI at position P3, binding pocket D and residue RKHYFMLI at the C-terminal, binding to HLA pocket F. Restricting HLA is B*2705 [Nixon et al.Nature 336:484-487 (1988)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58792

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HXB2 Location	Gag(275-282) p24(143-150) DNA(1612..1635)	Gag Epitope Map
Author Location	p24(275-282)
Epitope	`RMYSPTSI`	Epitope Alignment
Species (MHC/HLA)	human(B*52:01)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope RMYSPTSI has residue Q at position P2, binding to HLA pocket B; FYW at position P3, binding pocket D and residue IV at the C-terminal, binding to HLA pocket F. Restricting HLA is B*5201 [Brander et al. JVI 73:10191-10198 (1999)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58787

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HXB2 Location	Gag(298-306) p24(166-174) DNA(1681..1707)	Gag Epitope Map
Author Location	p24(298-306)
Epitope	`DRFFKTLRA`	Epitope Alignment
Species (MHC/HLA)	human(B*14:02)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope DRFFKTLRA has residue DE at position P1, binding pocket A; RK at position P2, binding to HLA pocket B; YFL at position P3, binding pocket D and residue L at the C-terminal, binding to HLA pocket F. Restricting HLA is B*1402 [Harrer et al. J Immunol. 156:2616-2623 (1996)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58790

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HXB2 Location	Gag(306-316) p24(174-184) DNA(1705..1737)	Gag Epitope Map
Author Location	p24(306-316)
Epitope	`AEQATQDVKNW`	Epitope Alignment
Species (MHC/HLA)	human(B*44:03)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p24 Gag epitope AEQATQDVKNW has residue DA at position P1, binding pocket A; E at position P2, binding to HLA pocket B; M at position P3, binding pocket D and residue YF at the C-terminal, binding to HLA pocket F. Restricting HLA is B*4403 [Kiepiela et al. Nature Med. 13:46-53 (2007)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58785

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HXB2 Location	Gag(429-437) p2p7p1p6(66-74) DNA(2074..2100)	Gag Epitope Map
Author Location	p15(429-437)
Epitope	`RQANFLGKI`	Epitope Alignment
Species (MHC/HLA)	human(B*13:02)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
p15 Gag epitope RQANFLGKI has residue QML at position P2, binding to HLA pocket B and residue LIV at the C-terminal, binding to HLA pocket F. Restricting HLA is B*1302 [Honeyborne et al. JVI 81:3667-3672 (2007)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 58797

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HXB2 Location	Pol(547-556) RT(392-401) DNA(3723..3752)	Pol Epitope Map
Author Location	RT(559-568)
Epitope	`PIQKETWETW`	Epitope Alignment
Species (MHC/HLA)	human(A*32:01)
Immunogen
Experimental methods
Keywords	review

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
RT epitope PIQKETWETW has residue IQ at position P2, binding to HLA pocket B; and residue W at the C-terminal, binding to HLA pocket F. Restricting HLA is A*3201 [Harrer et al. J Immunol. 156:2616-2623 (1996)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61599

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HXB2 Location	Vif(63-70) DNA(5227..5250)	Vif Epitope Map
Author Location	Vif(66-73)
Epitope	`HLEVQGYW`	Epitope Alignment
Species (MHC/HLA)	macaque(Mamu B*17)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Vif epitope HLEVQGYW is Mamu B*17-restricted [Mothe et al. JI 169(1):210-219 (2002)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61596

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HXB2 Location	Vif DNA(1207..1239)	Vif Epitope Map
Author Location	Vif(172-179)
Epitope	`RRDNRRGL`	Epitope Alignment
Species (MHC/HLA)	macaque(Mamu B*08)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Vif epitope RRDNRRGL is Mamu B*08-restricted [Maness et al. JVI 82:5245-5254 (2008)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61595

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HXB2 Location	Vif DNA(1207..1239)	Vif Epitope Map
Author Location	Vif(123-131)
Epitope	`RRAIRGEQL`	Epitope Alignment
Species (MHC/HLA)	macaque(Mamu B*08)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Vif epitope RRAIRGEQL is Mamu B*08-restricted [Maness et al. JVI 82:5245-5254 (2008)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61594

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HXB2 Location	Nef(105-114) DNA(9109..9138)	Nef Epitope Map
Author Location	Nef(137-146)
Epitope	`RRHRILDIYL`	Epitope Alignment
Epitope Name	Nef_137-146RL10
Species (MHC/HLA)	macaque(Mamu B*08)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Nef epitope CTPYDINQM has residue R at position P2, residue R at position P3, binding to HLA pocket B; and residues L at the C-terminal, binding to HLA pocket F. Restricting HLA is Mamu B*08 [Maness et al. JVI 82:5245-5254 (2008)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61597

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HXB2 Location	Nef(133-141) DNA(9193..9219)	Nef Epitope Map
Author Location	Nef(165-173)
Epitope	`IRYPKTFGW`	Epitope Alignment
Species (MHC/HLA)	macaque(Mamu B*17)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Nef epitope IRYPKTFGW has residue RHL at position P2, binding to HLA pocket B; and residue W at the C-terminal, binding to HLA pocket F. Restricting HLA is Mamu B*17 [Mothe et al. JI 169(1):210-219 (2002)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.

Displaying record number 61598

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HXB2 Location	Nef DNA(1207..1239)	Nef Epitope Map
Author Location	Nef(195-203)
Epitope	`MHPAQTSQW`	Epitope Alignment
Epitope Name	SIVNefMW9
Species (MHC/HLA)	macaque(Mamu B*17)
Immunogen	SIV infection
Experimental methods
Keywords	review, SIV

Notes

The authors review the interaction between HLA-B alleles and epitopes that are able to control viral evolution.
SIV Nef epitope MHPAQTSQW his Mamu B*17-restricted [Mothe et al. JI 169(1):210-219 (2002)].

References

Goulder2012 Philip J. R. Goulder and Bruce D. Walker. HIV and HLA Class I: An Evolving Relationship. Immunity, 37(3):426-440, 21 Sep 2012. PubMed ID: 22999948. Show all entries for this paper.