HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 7 matching records:

Displaying record number 139

HXB2 Location Gag(147-155)
p24(15-23)
DNA(1228..1254)
Gag Epitope Map
Author Location p24(147-155 IIIB)
Epitope ISPRTLNAW Epitope Alignment
ISPRTLNAW epitope logo
Species (MHC/HLA) human(B*5801, B57)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression

Notes

References

Goulder1996 P. J. R. Goulder, M. Bunce, P. Krausa, K. McIntyre, S. Crowley, B. Morgan, A. Edwards, P. Giangrande, R. E. Phillips, and A. J. McMichael. Novel, Cross-Restricted, Conserved and Immunodominant Cytotoxic T Lymphocyte Epitopes in Slow HIV Type 1 Infection. AIDS Res. Hum. Retroviruses, 12:1691-1698, 1996. HLA-B*57 is over-represented in slow progressors. HLA*5801 is a closely related molecule, and while the defined anchor residues of HLA*5801 can be used to predict epitopes in HIV-1 proteins, the CTL from HLA-B*57 positive individuals have limited cross-presentation capacity with HLA*5801 targets. In this paper five new HLA-B*57 epitopes were defined. PubMed ID: 8959245. Show all entries for this paper.


Displaying record number 162

HXB2 Location Gag(162-172)
p24(30-40)
DNA(1273..1305)
Gag Epitope Map
Author Location p24(162-172 LAI)
Epitope KAFSPEVIPMF Epitope Alignment
KAFSPEVIPMF epitope logo
Subtype B
Species (MHC/HLA) human(B*5701)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression

Notes

References

Goulder1996 P. J. R. Goulder, M. Bunce, P. Krausa, K. McIntyre, S. Crowley, B. Morgan, A. Edwards, P. Giangrande, R. E. Phillips, and A. J. McMichael. Novel, Cross-Restricted, Conserved and Immunodominant Cytotoxic T Lymphocyte Epitopes in Slow HIV Type 1 Infection. AIDS Res. Hum. Retroviruses, 12:1691-1698, 1996. HLA-B*57 is over-represented in slow progressors. HLA*5801 is a closely related molecule, and while the defined anchor residues of HLA*5801 can be used to predict epitopes in HIV-1 proteins, the CTL from HLA-B*57 positive individuals have limited cross-presentation capacity with HLA*5801 targets. In this paper five new HLA-B*57 epitopes were defined. PubMed ID: 8959245. Show all entries for this paper.


Displaying record number 225

HXB2 Location Gag(240-249)
p24(108-117)
DNA(1507..1536)
Gag Epitope Map
Author Location p24(240-249)
Epitope TSTLQEQIGW Epitope Alignment
TSTLQEQIGW epitope logo
Subtype B
Species (MHC/HLA) human(B*58)
Immunogen HIV-1 or HIV-2 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, rate of progression, immunodominance, variant cross-reactivity, HIV-2

Notes

References

Bertoletti1998 A. Bertoletti, F. Cham, S. McAdam, T. Rostron, S. Rowland-Jones, S. Sabally, T. Corrah, K. Ariyoshi, and H. Whittle. Cytotoxic T cells from human immunodeficiency virus type 2-infected patients frequently cross-react with different human immunodeficiency virus type 1 clades. J. Virol., 72:2439-2448, 1998. PubMed ID: 9499105. Show all entries for this paper.

Goulder1996 P. J. R. Goulder, M. Bunce, P. Krausa, K. McIntyre, S. Crowley, B. Morgan, A. Edwards, P. Giangrande, R. E. Phillips, and A. J. McMichael. Novel, Cross-Restricted, Conserved and Immunodominant Cytotoxic T Lymphocyte Epitopes in Slow HIV Type 1 Infection. AIDS Res. Hum. Retroviruses, 12:1691-1698, 1996. HLA-B*57 is over-represented in slow progressors. HLA*5801 is a closely related molecule, and while the defined anchor residues of HLA*5801 can be used to predict epitopes in HIV-1 proteins, the CTL from HLA-B*57 positive individuals have limited cross-presentation capacity with HLA*5801 targets. In this paper five new HLA-B*57 epitopes were defined. PubMed ID: 8959245. Show all entries for this paper.


Displaying record number 59066

HXB2 Location Gag(240-249)
p24(108-117)
DNA(1507..1536)
Gag Epitope Map
Author Location Gag
Epitope TSTVEEQIQW Epitope Alignment
TSTVEEQIQW epitope logo
Subtype HIV-2
Species (MHC/HLA) human(B*58)
Immunogen HIV-2 infection
Experimental methods CD8 T-cell Elispot - IFNγ
Keywords subtype comparisons, rate of progression, immunodominance, HIV-2

Notes

References

Bertoletti1998 A. Bertoletti, F. Cham, S. McAdam, T. Rostron, S. Rowland-Jones, S. Sabally, T. Corrah, K. Ariyoshi, and H. Whittle. Cytotoxic T cells from human immunodeficiency virus type 2-infected patients frequently cross-react with different human immunodeficiency virus type 1 clades. J. Virol., 72:2439-2448, 1998. PubMed ID: 9499105. Show all entries for this paper.

Goulder1996 P. J. R. Goulder, M. Bunce, P. Krausa, K. McIntyre, S. Crowley, B. Morgan, A. Edwards, P. Giangrande, R. E. Phillips, and A. J. McMichael. Novel, Cross-Restricted, Conserved and Immunodominant Cytotoxic T Lymphocyte Epitopes in Slow HIV Type 1 Infection. AIDS Res. Hum. Retroviruses, 12:1691-1698, 1996. HLA-B*57 is over-represented in slow progressors. HLA*5801 is a closely related molecule, and while the defined anchor residues of HLA*5801 can be used to predict epitopes in HIV-1 proteins, the CTL from HLA-B*57 positive individuals have limited cross-presentation capacity with HLA*5801 targets. In this paper five new HLA-B*57 epitopes were defined. PubMed ID: 8959245. Show all entries for this paper.


Displaying record number 219

HXB2 Location Gag(240-250)
p24(108-118)
DNA(1507..1539)
Gag Epitope Map
Author Location p24(240-249 LAI)
Epitope TSTLQEQIGWF Epitope Alignment
TSTLQEQIGWF epitope logo
Subtype B
Species (MHC/HLA) human(B*57, B*5801)
Immunogen HIV-1 infection
Experimental methods  
Keywords rate of progression

Notes

References

Goulder1996 P. J. R. Goulder, M. Bunce, P. Krausa, K. McIntyre, S. Crowley, B. Morgan, A. Edwards, P. Giangrande, R. E. Phillips, and A. J. McMichael. Novel, Cross-Restricted, Conserved and Immunodominant Cytotoxic T Lymphocyte Epitopes in Slow HIV Type 1 Infection. AIDS Res. Hum. Retroviruses, 12:1691-1698, 1996. HLA-B*57 is over-represented in slow progressors. HLA*5801 is a closely related molecule, and while the defined anchor residues of HLA*5801 can be used to predict epitopes in HIV-1 proteins, the CTL from HLA-B*57 positive individuals have limited cross-presentation capacity with HLA*5801 targets. In this paper five new HLA-B*57 epitopes were defined. PubMed ID: 8959245. Show all entries for this paper.


Displaying record number 341

HXB2 Location Gag(308-316)
p24(176-184)
DNA(1711..1737)
Gag Epitope Map
Author Location p24(309-317 LAI)
Epitope QASQEVKNW Epitope Alignment
QASQEVKNW epitope logo
Subtype B
Species (MHC/HLA) human(B*5701)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Goulder1996 P. J. R. Goulder, M. Bunce, P. Krausa, K. McIntyre, S. Crowley, B. Morgan, A. Edwards, P. Giangrande, R. E. Phillips, and A. J. McMichael. Novel, Cross-Restricted, Conserved and Immunodominant Cytotoxic T Lymphocyte Epitopes in Slow HIV Type 1 Infection. AIDS Res. Hum. Retroviruses, 12:1691-1698, 1996. HLA-B*57 is over-represented in slow progressors. HLA*5801 is a closely related molecule, and while the defined anchor residues of HLA*5801 can be used to predict epitopes in HIV-1 proteins, the CTL from HLA-B*57 positive individuals have limited cross-presentation capacity with HLA*5801 targets. In this paper five new HLA-B*57 epitopes were defined. PubMed ID: 8959245. Show all entries for this paper.


Displaying record number 1059

HXB2 Location Nef(130-143)
DNA(9184..9225)
Nef Epitope Map
Author Location Nef(130-143 LAI)
Epitope GPGVRYPLTFGWCY Epitope Alignment
GPGVRYPLTFGWCY epitope logo
Subtype B
Species (MHC/HLA) human(B*57)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Goulder1996 P. J. R. Goulder, M. Bunce, P. Krausa, K. McIntyre, S. Crowley, B. Morgan, A. Edwards, P. Giangrande, R. E. Phillips, and A. J. McMichael. Novel, Cross-Restricted, Conserved and Immunodominant Cytotoxic T Lymphocyte Epitopes in Slow HIV Type 1 Infection. AIDS Res. Hum. Retroviruses, 12:1691-1698, 1996. HLA-B*57 is over-represented in slow progressors. HLA*5801 is a closely related molecule, and while the defined anchor residues of HLA*5801 can be used to predict epitopes in HIV-1 proteins, the CTL from HLA-B*57 positive individuals have limited cross-presentation capacity with HLA*5801 targets. In this paper five new HLA-B*57 epitopes were defined. PubMed ID: 8959245. Show all entries for this paper.


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