HIV molecular immunology database
Found 9 matching records:
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| HXB2 Location | Nef(73-82) DNA(9013..9042) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(73-82 BRU) | |
| Epitope |
QVPLRPMTYK
|
Epitope Alignment
|
| Species (MHC/HLA) | human(A11, A3, B35) | |
| Immunogen | HIV-1 infection | |
| Experimental methods | ||
| Keywords |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
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| HXB2 Location | Nef(74-81) DNA(9016..9039) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(73-82 LAI) | |
| Epitope |
VPLRPMTY
|
Epitope Alignment
|
| Subtype | B | |
| Species (MHC/HLA) | human(B35) | |
| Immunogen | HIV-1 or HIV-2 infection | |
| Experimental methods | ||
| Keywords | review |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
McMichael1994 A. J. McMichael and B. D. Walker. Cytotoxic T Lymphocytes Epitopes: Implications for HIV Vaccine. AIDS, 8S:S155-S173, 1994. Comprehensive review summarizing CTL epitopes that have known HLA type and are fine mapped to indicate epitope boundaries. Anchor residues are indicated when known for different HLA restricted epitopes. Includes a summary of the published literature, as well as much work that was in press or submitted for publication. Show all entries for this paper.
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| HXB2 Location | Nef(83-94) DNA(9043..9078) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(83-94 BRU) | |
| Epitope |
AAVDLSHFLKEK
|
Epitope Alignment
|
| Species (MHC/HLA) | human(A11) | |
| Immunogen | HIV-1 infection | |
| Experimental methods | ||
| Keywords |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
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| HXB2 Location | Nef(115-125) DNA(9139..9171) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(115-125 BRU) | |
| Epitope |
YHTQGYFPDWQ
|
Epitope Alignment
|
| Species (MHC/HLA) | human(B17) | |
| Immunogen | HIV-1 infection | |
| Experimental methods | ||
| Keywords |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
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| HXB2 Location | Nef(116-125) DNA(9142..9171) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(116-125 BRU) | |
| Epitope |
HTQGYFPDWQ
|
Epitope Alignment
|
| Species (MHC/HLA) | human(B57) | |
| Immunogen | HIV-1 infection | |
| Experimental methods | ||
| Keywords |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
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| HXB2 Location | Nef(117-128) DNA(9145..9180) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(117-128 BRU) | |
| Epitope |
TQGYFPDWQNYT
|
Epitope Alignment
|
| Species (MHC/HLA) | human(B17, B37) | |
| Immunogen | HIV-1 infection | |
| Experimental methods | ||
| Keywords |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
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| HXB2 Location | Nef(126-138) DNA(9172..9210) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(126-138 BRU) | |
| Epitope |
NYTPGPGVRYPLT
|
Epitope Alignment
|
| Species (MHC/HLA) | human(B7) | |
| Immunogen | HIV-1 infection | |
| Experimental methods | ||
| Keywords |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
Download this epitope record as JSON.
| HXB2 Location | Nef(132-147) DNA(9190..9237) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(132-147 BRU) | |
| Epitope |
GVRYPLTFGWCYKLVP
|
Epitope Alignment
|
| Species (MHC/HLA) | human(B18) | |
| Immunogen | HIV-1 infection | |
| Experimental methods | ||
| Keywords |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
Download this epitope record as JSON.
| HXB2 Location | Nef(135-143) DNA(9199..9225) |
Nef Epitope Map |
|---|---|---|
| Author Location | Nef(135-143 LAI) | |
| Epitope |
YPLTFGWCY
|
Epitope Alignment
|
| Subtype | B | |
| Species (MHC/HLA) | human(B18) | |
| Immunogen | HIV-1 exposed seronegative | |
| Experimental methods | ||
| Keywords |
Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.
CulmannPenciolelli1994 B. Culmann-Penciolelli, S. Lamhamedi-Cherradi, I. Couillin, N. Guegan, J. P. Levy, J. G. Guillet, and E. Gomard. Identification of multirestricted immunodominant regions recognized by cytolytic T lymphocytes in the human immunodeficiency virus type 1 Nef protein. J. Virol., 68:7336-43, 1994. See comments in J Virol 1995 Jan;69(1):618. PubMed ID: 7523699. Show all entries for this paper.