HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 9 matching records:

Displaying record number 979

HXB2 Location Nef(73-82)
DNA(9013..9042)
Nef Epitope Map
Author Location Nef(73-82 BRU)
Epitope QVPLRPMTYK Epitope Alignment
QVPLRPMTYK epitope logo
Species (MHC/HLA) human(A11, A3, B35)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.


Displaying record number 988

HXB2 Location Nef(74-81)
DNA(9016..9039)
Nef Epitope Map
Author Location Nef(73-82 LAI)
Epitope VPLRPMTY Epitope Alignment
VPLRPMTY epitope logo
Subtype B
Species (MHC/HLA) human(B35)
Immunogen HIV-1 or HIV-2 infection
Experimental methods  
Keywords review

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.

McMichael1994 A. J. McMichael and B. D. Walker. Cytotoxic T Lymphocytes Epitopes: Implications for HIV Vaccine. AIDS, 8S:S155-S173, 1994. Comprehensive review summarizing CTL epitopes that have known HLA type and are fine mapped to indicate epitope boundaries. Anchor residues are indicated when known for different HLA restricted epitopes. Includes a summary of the published literature, as well as much work that was in press or submitted for publication. Show all entries for this paper.


Displaying record number 1002

HXB2 Location Nef(83-94)
DNA(9043..9078)
Nef Epitope Map
Author Location Nef(83-94 BRU)
Epitope AAVDLSHFLKEK Epitope Alignment
AAVDLSHFLKEK epitope logo
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.


Displaying record number 1033

HXB2 Location Nef(115-125)
DNA(9139..9171)
Nef Epitope Map
Author Location Nef(115-125 BRU)
Epitope YHTQGYFPDWQ Epitope Alignment
YHTQGYFPDWQ epitope logo
Species (MHC/HLA) human(B17)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.


Displaying record number 1035

HXB2 Location Nef(116-125)
DNA(9142..9171)
Nef Epitope Map
Author Location Nef(116-125 BRU)
Epitope HTQGYFPDWQ Epitope Alignment
HTQGYFPDWQ epitope logo
Species (MHC/HLA) human(B57)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.


Displaying record number 1040

HXB2 Location Nef(117-128)
DNA(9145..9180)
Nef Epitope Map
Author Location Nef(117-128 BRU)
Epitope TQGYFPDWQNYT Epitope Alignment
TQGYFPDWQNYT epitope logo
Species (MHC/HLA) human(B17, B37)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.


Displaying record number 1049

HXB2 Location Nef(126-138)
DNA(9172..9210)
Nef Epitope Map
Author Location Nef(126-138 BRU)
Epitope NYTPGPGVRYPLT Epitope Alignment
NYTPGPGVRYPLT epitope logo
Species (MHC/HLA) human(B7)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.


Displaying record number 1062

HXB2 Location Nef(132-147)
DNA(9190..9237)
Nef Epitope Map
Author Location Nef(132-147 BRU)
Epitope GVRYPLTFGWCYKLVP Epitope Alignment
GVRYPLTFGWCYKLVP epitope logo
Species (MHC/HLA) human(B18)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.


Displaying record number 1070

HXB2 Location Nef(135-143)
DNA(9199..9225)
Nef Epitope Map
Author Location Nef(135-143 LAI)
Epitope YPLTFGWCY Epitope Alignment
YPLTFGWCY epitope logo
Subtype B
Species (MHC/HLA) human(B18)
Immunogen HIV-1 exposed seronegative
Experimental methods  
Keywords  

Notes

References

Culmann1991 B. Culmann, E. Gomard, M.-P. Kieny, B. Guy, F. Dreyfus, A.-D. Saimot, D. Sereni, D. Sicard, and J.-P. Levy. Six Epitopes with Human Cytotoxic CD8+ Cells in the Central Region of the HIV-1 Nef Protein. J. Immunol., 146:1560-1565, 1991. Nef-specific CTL were generated from six seropositive donors. Six epitopes were defined, all localized to two regions in the central part of Nef. Some epitopes could be recognized in the contexts of several HLA class I molecules. Peptides were based on BRU epitopes: QVPLRPMTYK, HLA A3, A11, B35; AAVDLSHFLKEK, HLA A11; HTQGYFPQWQ, HLA B17;TQGYFPQWQNYT, HLA B17, B37, NYTPGPGVRYPLT, HLA B7; and GVRYPLTFGWCYKLVP, HLA B18). PubMed ID: 1704397. Show all entries for this paper.

CulmannPenciolelli1994 B. Culmann-Penciolelli, S. Lamhamedi-Cherradi, I. Couillin, N. Guegan, J. P. Levy, J. G. Guillet, and E. Gomard. Identification of multirestricted immunodominant regions recognized by cytolytic T lymphocytes in the human immunodeficiency virus type 1 Nef protein. J. Virol., 68:7336-43, 1994. See comments in J Virol 1995 Jan;69(1):618. PubMed ID: 7523699. Show all entries for this paper.


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