HIV molecular immunology database

 

Search CTL/CD8+ T-Cell Epitope Database

Found 2 matching records:

Displaying record number 982

HXB2 Location Nef(73-82)
DNA(9013..9042)
Nef Epitope Map
Author Location Nef(73-82 LAI)
Epitope QVPLRPMTYK Epitope Alignment
QVPLRPMTYK epitope logo
Subtype B
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Couillin1995 I. Couillin, F. Connan, B. Culmann-Penciolelli, E. Gomard, J.-G. Guillet, and J. Choppin. HLA-Dependent Variations in Human Immunodeficiency Virus Nef Protein Alter Peptide/HLA binding. Eur. J. Immunol., 25:728-732, 1995. Viral sequences across this region were compared from 3 HLA-A11 positive and 10 negative donors. Substitutions that were found only in the 3 HLA-A11 donors did not promote HLA-A11 assembly. Substitutions that were found in both HLA-A11 positive and negative donors, however, did not markedly alter the reactivity of the peptides. This suggests that substitutions that result in loss of HLA-A11 occur mainly in HLA-A11 positive donors. PubMed ID: 7705402. Show all entries for this paper.


Displaying record number 1008

HXB2 Location Nef(84-92)
DNA(9046..9072)
Nef Epitope Map
Author Location Nef(84-92 LAI)
Epitope AVDLSHFLK Epitope Alignment
AVDLSHFLK epitope logo
Subtype B
Species (MHC/HLA) human(A11)
Immunogen HIV-1 infection
Experimental methods  
Keywords  

Notes

References

Couillin1995 I. Couillin, F. Connan, B. Culmann-Penciolelli, E. Gomard, J.-G. Guillet, and J. Choppin. HLA-Dependent Variations in Human Immunodeficiency Virus Nef Protein Alter Peptide/HLA binding. Eur. J. Immunol., 25:728-732, 1995. Viral sequences across this region were compared from 3 HLA-A11 positive and 10 negative donors. Substitutions that were found only in the 3 HLA-A11 donors did not promote HLA-A11 assembly. Substitutions that were found in both HLA-A11 positive and negative donors, however, did not markedly alter the reactivity of the peptides. This suggests that substitutions that result in loss of HLA-A11 occur mainly in HLA-A11 positive donors. PubMed ID: 7705402. Show all entries for this paper.


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