Search CTL/CD8+ T-Cell Epitope Database

Found 20 matching records:

Displaying record number 1850

HXB2 Location	Gag(77-85) p17(77-85) DNA(1018..1044)	Gag Epitope Map
Author Location	p17( SF2)
Epitope	`SLYNTVATL`	Epitope Alignment
Species (MHC/HLA)	human(A2)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD8 dependent, but the HLA presenting molecule and optimal epitope were not determined.

References

Altfeld2000 M. A. Altfeld, A. Trocha, R. L. Eldridge, E. S. Rosenberg, M. N. Phillips, M. M. Addo, R. P. Sekaly, S. A. Kalams, S. A. Burchett, K. McIntosh, B. D. Walker, and P. J. Goulder. Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay. J. Virol., 74:8541, 2000. PubMed ID: 10954555. Show all entries for this paper.

Displaying record number 1844

HXB2 Location	Gag(86-101) p17(86-101) DNA(1045..1092)	Gag Epitope Map
Author Location	p17( SF2)
Epitope	`YCVHQRIEIKDTKEAL`	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD8 dependent, but the HLA presenting molecule and optimal epitope were not determined.

References

Displaying record number 1851

HXB2 Location	Gag(86-101) p17(86-101) DNA(1045..1092)	Gag Epitope Map
Author Location	p17( SF2)
Epitope	`YCVHQRIEIKDTKEAL`	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD8 dependent, but the HLA presenting molecule and optimal epitope were not determined.

References

Displaying record number 1840

HXB2 Location	Gag(92-101) p17(92-101) DNA(1063..1092)	Gag Epitope Map
Author Location	p17( SF2)
Epitope	`IEIKDTKEAL`	Epitope Alignment
Species (MHC/HLA)	human(B60)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes.
B60 is present in 10-20% of the Caucasoid and very common in Asian populations.

References

Displaying record number 1852

HXB2 Location	Gag(163-182) p24(31-50) DNA(1276..1335)	Gag Epitope Map
Author Location	p24( SF2)
Epitope	`AFSPEVIPMFSALSEGATPQ`	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD4 dependent, but the HLA presenting molecule and optimal epitope were not determined.

References

Displaying record number 1853

HXB2 Location	Gag(173-192) p24(41-60) DNA(1306..1365)	Gag Epitope Map
Author Location	p24( SF2)
Epitope	`SALSEGATPQDLNTMLNTVG`	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD8 dependent, but the HLA presenting molecule and optimal epitope were not determined.

References

Displaying record number 1842

HXB2 Location	Gag(176-184) p24(44-52) DNA(1315..1341)	Gag Epitope Map
Author Location	p24( SF2)
Epitope	`SEGATPQDL`	Epitope Alignment
Species (MHC/HLA)	human(B60)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes.
B60 is present in 10-20% of the Caucasoid and very common in Asian populations.

References

Displaying record number 1845

HXB2 Location	Gag(298-306) p24(166-174) DNA(1681..1707)	Gag Epitope Map
Author Location	p24( SF2)
Epitope	`DRFYKTLRA`	Epitope Alignment
Species (MHC/HLA)	human(B14)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.

References

Displaying record number 1854

HXB2 Location	Pol(353-367) RT(198-212) DNA(3141..3185)	Pol Epitope Map
Author Location	RT( SF2)
Epitope	`HRTKIEELRQHLLRW`	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD8 dependent, but the HLA presenting molecule and optimal epitope were not determined.

References

Displaying record number 1201

HXB2 Location	Pol(357-365) RT(202-210) DNA(3153..3179)	Pol Epitope Map
Author Location	RT(202-210 LAI)
Epitope	`IEELRQHLL`	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*4001)
Immunogen
Experimental methods
Keywords	optimal epitope

Notes

C. Brander notes this is a B*4001 epitope.

References

Llano2019 Anuska Llano, Samandhy Cedeño, Sandra Silva Arrieta, and Christian Brander. The 2019 Optimal HIV CTL Epitopes Update: Growing Diversity in Epitope Length and HLA restriction. 2019. Show all entries for this paper.

Displaying record number 1841

HXB2 Location	Pol(357-365) RT(202-210) DNA(3153..3179)	Pol Epitope Map
Author Location	RT( SF2)
Epitope	`IEELRQHLL`	Epitope Alignment
Species (MHC/HLA)	human(B60)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes.
B60 is present in 10-20% of the Caucasoid and very common in Asian populations.

References

Displaying record number 1846

HXB2 Location	gp160(584-592) gp41(73-81) DNA(7974..8000)	gp160 Epitope Map
Author Location	gp41( SF2)
Epitope	`ERYLKDQQL`	Epitope Alignment
Species (MHC/HLA)	human(B14)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.

References

Displaying record number 1855

HXB2 Location	gp160(794-814) gp41(283-303) DNA(8604..8666)	gp160 Epitope Map
Author Location	gp41( SF2)
Epitope	`KYCWNLLQYWSQELKNSAVSL`	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD8 dependent, but the HLA presenting molecule and optimal epitope were not determined.

References

Displaying record number 1843

HXB2 Location	gp160(805-814) gp41(294-303) DNA(8637..8666)	gp160 Epitope Map
Author Location	gp41( SF2)
Epitope	`QELKNSAVSL`	Epitope Alignment
Species (MHC/HLA)	human(B60)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes.
B60 is present in 10-20% of the Caucasoid and very common in Asian populations.

References

Displaying record number 1857

HXB2 Location	gp160(843-851) gp41(332-340) DNA(8751..8777)	gp160 Epitope Map
Author Location	gp41( SF2)
Epitope	`IPRRIRQGL`	Epitope Alignment
Species (MHC/HLA)	human(B7)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.

References

Displaying record number 1847

HXB2 Location	Nef(73-82) DNA(9013..9042)	Nef Epitope Map
Author Location	Nef( SF2)
Epitope	`QVPLRPMTYK`	Epitope Alignment
Species (MHC/HLA)	human(A3)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.

References

Displaying record number 1848

HXB2 Location	Nef(82-91) DNA(9040..9069)	Nef Epitope Map
Author Location	Nef( SF2)
Epitope	`KAAVDLSHFL`	Epitope Alignment
Species (MHC/HLA)	human(Cw8)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.

References

Displaying record number 1839

HXB2 Location	Nef(92-100) DNA(9070..9096)	Nef Epitope Map
Author Location	Nef( SF2)
Epitope	`KEKGGLEGL`	Epitope Alignment
Species (MHC/HLA)	human(B60)
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was the dominant B60 (encoded by B*4001) response in 6/8 HLA-B60 individuals, and recognized in all eight.
This epitope was also recognized two expressing HLA-B61 individuals (B61 is usually encoded by B*4002, but this study did not distinguish between B*4002, B*4003, B*4004, B*4006, and B*4008)
ELISPOT was a rapid an effective method that was used to define five novel B60 epitopes.
HLA-B60 is present in 10-20% of the Caucasoid population and B60/B61 are very common in Asian populations.

References

Displaying record number 1849

HXB2 Location	Nef(92-112) DNA(9070..9132)	Nef Epitope Map
Author Location	Nef( SF2)
Epitope	`KEKGGLEGLIHSQRRQDILDL`	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD8 dependent, but the HLA presenting molecule and optimal epitope were not determined.

References

Displaying record number 1856

HXB2 Location	Nef(92-112) DNA(9070..9132)	Nef Epitope Map
Author Location	Nef( SF2)
Epitope	`KEKGGLEGLIHSQRRQDILDL`	Epitope Alignment
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords

Notes

This epitope was mapped by ELISPOT in a study identifying new HLA-B60 epitopes, and was one of the epitopes presented by another HLA molecule in an HLA-B60 individual.
The response to the peptide was CD8 dependent, but the HLA presenting molecule and optimal epitope were not determined.