Search CTL/CD8+ T-Cell Epitope Database

Found 26 matching records:

Displaying record number 52400

HXB2 Location	Vif(17-26) DNA(5089..5118)	Vif Epitope Map
Author Location	Vif(17-26)
Epitope	RIRTWKSLVK	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A*0301)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52396

HXB2 Location	Vif(27-41) DNA(5119..5163)	Vif Epitope Map
Author Location	Vif
Epitope	HHMYISKKAKGWGWFYR	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot -- 33% (23/70) targeted one or more Vif peptides, and this peptide was the most frequently recognized epitope in Vif (25%).
• The regulatory proteins Rev and Tat combined contributed to 3%, and the accessory proteins Vif, Vpr and Vpu to 7%, of the total magnitude of HIV-1 specific CTL responses in a subset of 22 HIV-1 infected individuals in whom all HIV-1 proteins were studied.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52399

HXB2 Location	Vif(28-36) DNA(5122..5148)	Vif Epitope Map
Author Location	Vif(28-36)
Epitope	HMYISKKAK	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A*0301)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52401

HXB2 Location	Vif(31-39) DNA(5131..5157)	Vif Epitope Map
Author Location	Vif(31-39)
Epitope	ISKKAKGWF	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*5701)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52402

HXB2 Location	Vif(48-57) DNA(5182..5211)	Vif Epitope Map
Author Location	Vif(48-57)
Epitope	HPRVSSEVHI	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*0702)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52404

HXB2 Location	Vif(102-111) DNA(5344..5373)	Vif Epitope Map
Author Location	Vif(102-111)
Epitope	LADQLIHLHY	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*1801)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52403

HXB2 Location	Vif(158-168) DNA(5512..5544)	Vif Epitope Map
Author Location	Vif(158-168)
Epitope	KTKPPLPSVKK	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A*0301)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52405

HXB2 Location	Vpr(12-20) DNA(5592..5618)	Vpr Epitope Map
Author Location	Vpr(12-20)
Epitope	REPHNEWTL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*4002)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52406

HXB2 Location	Vpr(30-38) DNA(5646..5672)	Vpr Epitope Map
Author Location	Vpr(29-38)
Epitope	AVRHFPRIW	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*5701)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52408

HXB2 Location	Vpr(34-42) DNA(5658..5684)	Vpr Epitope Map
Author Location	Vpr(34-42)
Epitope	FPRIWLHGL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*0702)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52407

HXB2 Location	Vpr(34-42) DNA(5658..5684)	Vpr Epitope Map
Author Location	Vpr(34-42)
Epitope	FPRIWLHGL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*8101)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52397

HXB2 Location	Vpr(55-70) DNA(5721..5768)	Vpr Epitope Map
Author Location	Vpr
Epitope	AGVEAIIRILQQLLFI	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot -- 40% (28/70) targeted one or more Vpr peptides, and this peptide was the most frequently recognized epitope in Vpr (41%).
• The regulatory proteins Rev and Tat combined contributed to 3%, and the accessory proteins Vif, Vpr and Vpu to 7%, of the total magnitude of HIV-1 specific CTL responses in a subset of 22 HIV-1 infected individuals in whom all HIV-1 proteins were studied.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52409

HXB2 Location	Vpr(59-67) DNA(5733..5759)	Vpr Epitope Map
Author Location	Vpr(58-66)
Epitope	AIIRILQQL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A*0201)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52410

HXB2 Location	Vpr(62-70) DNA(5742..5768)	Vpr Epitope Map
Author Location	Vpr(62-70)
Epitope	RILQQLLFI	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A*0201)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52413

HXB2 Location	Tat(2-11) DNA(5834..5863)	Tat Epitope Map
Author Location	Tat(2-11)
Epitope	EPVDPRLEPW	Epitope Alignment
Species (MHC/HLA)	human(B53)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52414

HXB2 Location	Tat(17-26) DNA(5879..5908)	Tat Epitope Map
Author Location	Tat(17-26)
Epitope	QPKTACTTCY	Epitope Alignment
Species (MHC/HLA)	human(B35)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52394

HXB2 Location	Tat(36-52) DNA(5936..5986)	Tat Epitope Map
Author Location	Tat
Epitope	VCFTTKALGISYGRKKR	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot -- 28% (19/70) targeted one or more Tat peptides, and this peptide was the most frequently recognized epitope in Tat (27%).
• The regulatory proteins Rev and Tat combined contributed to 3%, and the accessory proteins Vif, Vpr and Vpu to 7%, of the total magnitude of HIV-1 specific CTL responses in a subset of 22 HIV-1 infected individuals in whom all HIV-1 proteins were studied.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52415

HXB2 Location	Tat(39-49) DNA(5945..5977)	Tat Epitope Map
Author Location	Tat(38-48)
Epitope	ITKGLGISYGR	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A68)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52418

HXB2 Location	Rev(14-23) DNA(6009..6038)	Rev Epitope Map
Author Location	Rev(14-23)
Epitope	KAVRRLIKFLY	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*5701)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52419

HXB2 Location	Rev(14-23) DNA(6009..6038)	Rev Epitope Map
Author Location	Rev(14-23)
Epitope	KAVRRLIKFLY	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B*5801)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52420

HXB2 Location	Rev(58-66) DNA(8474..8500)	Rev Epitope Map
Author Location	Rev(58-66)
Epitope	RILSTYLGR	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A*0301)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52395

HXB2 Location	Rev(66-81) DNA(8498..8545)	Rev Epitope Map
Author Location	Rev
Epitope	RSAEPVPLQLPPLERL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot -- 36% (25/70) targeted one or more Rev peptides, and this peptide was the most frequently recognized epitope in Rev (32%).
• The regulatory proteins Rev and Tat combined contributed to 3%, and the accessory proteins Vif, Vpr and Vpu to 7%, of the total magnitude of HIV-1 specific CTL responses in a subset of 22 HIV-1 infected individuals in whom all HIV-1 proteins were studied.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52417

HXB2 Location	Rev(67-75) DNA(8501..8527)	Rev Epitope Map
Author Location	Rev(67-75)
Epitope	SAEPVPLQL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(B14)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52416

HXB2 Location	Rev(67-75) DNA(8501..8527)	Rev Epitope Map
Author Location	Rev(67-75)
Epitope	SAEPVPLQL	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(Cw5, Cw8)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52398

HXB2 Location	Vpu(25-40) DNA(6134..6181)	Vpu Epitope Map
Author Location	Vpu
Epitope	IVFIEYRKLRQRKID	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot -- only 2% (2/70) targeted one or more Vpu peptides, including this peptide.
• The regulatory proteins Rev and Tat combined contributed to 3%, and the accessory proteins Vif, Vpr and Vpu to 7%, of the total magnitude of HIV-1 specific CTL responses in a subset of 22 HIV-1 infected individuals in whom all HIV-1 proteins were studied.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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Displaying record number 52411

HXB2 Location	Vpu(29-37) DNA(6146..6172)	Vpu Epitope Map
Author Location	Vpu(29-37)
Epitope	EYRKILRQR	Epitope Alignment
Subtype	B
Species (MHC/HLA)	human(A*3303)
Immunogen	HIV-1 infection
Experimental methods
Keywords	early-expressed proteins

Notes

• CTL responses against regulatory and accessory proteins in 70 HIV-1 infected patients were studied using overlapping peptides and Elispot.
• 28% targeted one or more overlapping Tat peptides; 36%, Rev peptides; 33%, Vif peptides; 40%, Vpr peptides; and 2%, Vpu peptides.
• All known optimally defined epitopes were summarized for the five proteins.

References

Addo2002a M. M. Addo, X. G. Yu, E. S. Rosenberg, B. D. Walker, and M. Altfeld. Cytotoxic T-Lymphocyte (CTL) Responses Directed against Regulatory and Accessory Proteins in HIV-1 Infection. DNA Cell Biol., 21(9):671-678, Sep 2002. PubMed ID: 12396610. Show all entries for this paper.

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