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Displaying record number 3289

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MAb ID VRC26.26 (CAP256-VRC26.26)
HXB2 Location Env Env Epitope Map
Author Location  
Epitope
Subtype C
Ab Type gp120 V2 // V2 glycan(V2g) // V2 apex, quaternary structure
Neutralizing P (tier 2)  View neutralization details
Contacts and Features View contacts and features
Species (Isotype) human
Patient CAP256
Immunogen HIV-1 infection
Keywords antibody binding site, antibody generation, antibody lineage, antibody sequence, broad neutralizer, computational epitope prediction, escape, mutation acquisition, neutralization, structure, vaccine antigen design

Notes

Showing 4 of 4 notes.

References

Showing 4 of 4 references.

Isolation Paper
Doria-Rose2016 Nicole A. Doria-Rose, Jinal N. Bhiman, Ryan S. Roark, Chaim A. Schramm, Jason Gorman, Gwo-Yu Chuang, Marie Pancera, Evan M. Cale, Michael J. Ernandes, Mark K. Louder, Mangaiarkarasi Asokan, Robert T. Bailer, Aliaksandr Druz, Isabella R. Fraschilla, Nigel J. Garrett, Marissa Jarosinski, Rebecca M. Lynch, Krisha McKee, Sijy O'Dell, Amarendra Pegu, Stephen D. Schmidt, Ryan P. Staupe, Matthew S. Sutton, Keyun Wang, Constantinos Kurt Wibmer, Barton F. Haynes, Salim Abdool-Karim, Lawrence Shapiro, Peter D. Kwong, Penny L. Moore, Lynn Morris, and John R. Mascola. New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency. J. Virol., 90(1):76-91, 14 Oct 2015. PubMed ID: 26468542. Show all entries for this paper.

Bhiman2015 Jinal N. Bhiman, Colin Anthony, Nicole A. Doria-Rose, Owen Karimanzira, Chaim A. Schramm, Thandeka Khoza, Dale Kitchin, Gordon Botha, Jason Gorman, Nigel J. Garrett, Salim S. Abdool Karim, Lawrence Shapiro, Carolyn Williamson, Peter D. Kwong, John R. Mascola, Lynn Morris, and Penny L. Moore. Viral Variants That Initiate and Drive Maturation of V1V2-Directed HIV-1 Broadly Neutralizing Antibodies. Nat. Med., 21(11):1332-1336, Nov 2015. PubMed ID: 26457756. Show all entries for this paper.

Bricault2019 Christine A. Bricault, Karina Yusim, Michael S. Seaman, Hyejin Yoon, James Theiler, Elena E. Giorgi, Kshitij Wagh, Maxwell Theiler, Peter Hraber, Jennifer P. Macke, Edward F. Kreider, Gerald H. Learn, Beatrice H. Hahn, Johannes F. Scheid, James M. Kovacs, Jennifer L. Shields, Christy L. Lavine, Fadi Ghantous, Michael Rist, Madeleine G. Bayne, George H. Neubauer, Katherine McMahan, Hanqin Peng, Coraline Chéneau, Jennifer J. Jones, Jie Zeng, Christina Ochsenbauer, Joseph P. Nkolola, Kathryn E. Stephenson, Bing Chen, S. Gnanakaran, Mattia Bonsignori, LaTonya D. Williams, Barton F. Haynes, Nicole Doria-Rose, John R. Mascola, David C. Montefiori, Dan H. Barouch, and Bette Korber. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host Microbe, 25(1):59-72.e8, 9 Jan 2019. PubMed ID: 30629920. Show all entries for this paper.

Johnson2018 Erik L. Johnson, Nicole A. Doria-Rose, Jason Gorman, Jinal N. Bhiman, Chaim A. Schramm, Ashley Q. Vu, William H. Law, Baoshan Zhang, Valerie Bekker, Salim S. Abdool Karim, Gregory C. Ippolito, Lynn Morris, Penny L. Moore, Peter D. Kwong, John R. Mascola, and George Georgiou. Sequencing HIV-Neutralizing Antibody Exons and Introns Reveals Detailed Aspects of Lineage Maturation. Nat. Commun., 9(1):4136, 8 Oct 2018. PubMed ID: 30297708. Show all entries for this paper.


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