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HIV Molecular Immunology Database

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Displaying record number 1257

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MAb ID 14D9
HXB2 Location Env(662-667)
DNA(8208..8225)
Env Epitope Map
Author Location gp41(669-674 MVP5180)
Epitope ELDEWA Epitope Alignment
ELDEWA epitope logo
Subtype B, CRF01_AE, O group
Ab Type gp41 adjacent to cluster II, C-term, gp41 MPER (membrane proximal external region)
Neutralizing  
Species (Isotype) mouse(IgG1)
Patient  
Immunogen vaccine
Keywords antibody binding site, antibody generation, subtype comparisons, variant cross-reactivity

Vaccine Details

Vaccine type peptide keyhole limpet hemocyanin (KLH) conjugate
Vaccine strain natural variants
Vaccine component gp41
Adjuvant Complete Freund's Adjuvant (CFA)

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Isolation Paper
Huang2002 Jin Huang, Xiaonan Dong, Zuqiang Liu, Li Qin, and Ying-Hua Chen. A Predefined Epitope-Specific Monoclonal Antibody Recognizes ELDEWA-Epitope Just Presenting on gp41 of HIV-1 O Clade. Immunol. Lett., 84(3):205-209, 3 Dec 2002. PubMed ID: 12413738. Show all entries for this paper.

Kanduc2008 Darja Kanduc, Rosario Serpico, Alberta Lucchese, and Yehuda Shoenfeld. Correlating Low-Similarity Peptide Sequences and HIV B-Cell Epitopes. Autoimmun. Rev., 7(4):291-296, Feb 2008. PubMed ID: 18295732. Show all entries for this paper.


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