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MAb ID | 23A5G4 | |
---|---|---|
HXB2 Location | Gag(285-304) DNA(1642..1701) |
Gag Epitope Map |
Author Location | p24(285-304 IIIB) | |
Epitope |
IRQGPKEPFRDYVDRFYKTL
|
Epitope Alignment
|
Ab Type | ||
Neutralizing | ||
Species (Isotype) | mouse(IgG1) | |
Patient | ||
Immunogen | vaccine | |
Keywords |
Vaccine type | protein |
---|---|
Vaccine component | p24 Gag |
Showing 2 of 2 notes.
Showing 3 of 3 references.
Janvier1990 B. Janvier, P. Archinard, B. Mandrand, A. Goudeau, and F. Barin. Linear B-Cell Epitopes of the Major Core Protein of Human Immunodeficiency Virus Types 1 and 2. J. Virol., 64:4258-4263, 1990. PubMed ID: 1696638. Show all entries for this paper.
Janvier1992 B. Janvier, P. Archinard, B. Mandrand, A. Goudeau, and F. Barin. Linear B-Cell Epitopes of the Major Core Protein of Human Immunodeficiency Virus Types 1 and 2 (Author's Correction). J. Virol., 66:613, 1992. Show all entries for this paper.
Janvier1996 B. Janvier, J. J. Lasarte, P. Sarobe, J. Hoebeke, A. Baillou-Beaufils F. Borras-Cuesta, and F. Barin. B-Cell Epitopes of HIV Type 1 p24 Capsid Protein: A Reassessment. AIDS Res. Hum. Retroviruses, 12:519-525, 1996. The reactivity pattern of 45 overlapping synthetic pentadecapeptides, spanning amino acids 133 to 363 (p24) of HIV-1 p55 gag precursor, using sera from 20 HIV-1 positive and 8 HIV negative individuals was determined by ELISA. A peptide covering aa 178-192 was recognized by 40\%, and a peptide covering 288-302 of p55 by 45\%, of HIV-1 positive people. A peptide covering aa 272-322 of p55 was recognized by most human sera. A conformational epitope involving sequences from aa 183-186 and 289-292 was proposed, based by analogy to the structure of the Mengovirus VP2 protein. PubMed ID: 8679307. Show all entries for this paper.
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