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Displaying record number 863

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MAb ID	126-50
HXB2 Location	Env	Env Epitope Map
Author Location	gp41( HXB2)
Epitope	(Discontinuous epitope)
Subtype	B
Ab Type	gp41 cluster II
Neutralizing
Species (Isotype)	human(IgG2κ)
Patient
Immunogen	HIV-1 infection
Keywords	ADCC, review

Notes

Showing 2 matching of 5 total notes.

126-50: The complexity of the epitopes recognized by ADCC responses in HIV-1 infected individuals and candidate vaccine recipients is discussed in this review. 126-50 is discussed as the Cluster II (HR2)region-targeting, non-neutralizing anti-gp41 mAb exhibiting ADCC activity and having a discontinuous epitope. Pollara2013 (ADCC, review)
126-50: Directed antibody-dependent cellular cytotoxicity, ADCC. Tyler1990 (ADCC)

References

Showing 2 matching of 5 total references.

Pollara2013 Justin Pollara, Mattia Bonsignori, M. Anthony Moody, Marzena Pazgier, Barton F. Haynes, and Guido Ferrari. Epitope Specificity of Human Immunodeficiency Virus-1 Antibody Dependent Cellular Cytotoxicity (ADCC) Responses. Curr. HIV Res., 11(5):378-387, Jul 2013. PubMed ID: 24191939. Show all entries for this paper.

Tyler1990 D. S. Tyler, S. D. Stanley, S. Zolla-Pazner, M. K. Gorny, P. P. Shadduck, A. J. Langlois, T. J. Matthews, D. P. Bolognesi, T. J. Palker, and K. J. Weinhold. Identification of sites within gp41 that serve as targets for antibody-dependent cellular cytotoxicity by using human monoclonal antibodies. J. Immunol., 145:3276-3282, 1990. PubMed ID: 1700004. Show all entries for this paper.