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Displaying record number 577

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MAb ID	43F
HXB2 Location	gp160(491-500) DNA(7695..7724)	gp160 Epitope Map
Author Location	gp120(491-500 HXB2)
Epitope	IEPLGVAPTK	Epitope Alignment
Subtype	B
Ab Type	gp120 C5
Neutralizing
Species (Isotype)	human(IgG1λ)
Patient
Immunogen	HIV-1 infection
Keywords	ADCC, review

Notes

Showing 1 matching of 3 total notes.

• 43F: The complexity of the epitopes recognized by ADCC responses in HIV-1 infected individuals and candidate vaccine recipients is discussed in this review. 43F is discussed as the C5-targeting, non-neutralizing anti-gp120 mAb exhibiting ADCC activity and having a linear epitope. Pollara2013 (ADCC, review)

References

Showing 1 matching of 3 total references.

Pollara2013 Justin Pollara, Mattia Bonsignori, M. Anthony Moody, Marzena Pazgier, Barton F. Haynes, and Guido Ferrari. Epitope Specificity of Human Immunodeficiency Virus-1 Antibody Dependent Cellular Cytotoxicity (ADCC) Responses. Curr. HIV Res., 11(5):378-387, Jul 2013. PubMed ID: 24191939. Show all entries for this paper.