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Displaying record number 2894

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MAb ID	CH22
HXB2 Location	gp160(304-320) DNA(7134..7184)	gp160 Epitope Map
Author Location	gp120
Epitope	RKRIHIGPGRAFYTT	Epitope Alignment
Subtype	B, CRF01_AE
Ab Type	gp120 V3 // V3 glycan (V3g)
Neutralizing	yes
Species (Isotype)	human(IgG1)
Patient
Immunogen	vaccine
Country	Thailand
Keywords	ADCC, review

Notes

Showing 1 matching of 5 total notes.

• CH22: The complexity of the epitopes recognized by ADCC responses in HIV-1 infected individuals and candidate vaccine recipients is discussed in this review. CH22, generated by a vaccine recipient of phase II RV135 clinical trial, is discussed as the V3 region-targeting, neutralizing anti-gp120 mAb exhibiting ADCC activity and having a linear epitope. Pollara2013 (ADCC, review)

References

Showing 1 matching of 5 total references.

Pollara2013 Justin Pollara, Mattia Bonsignori, M. Anthony Moody, Marzena Pazgier, Barton F. Haynes, and Guido Ferrari. Epitope Specificity of Human Immunodeficiency Virus-1 Antibody Dependent Cellular Cytotoxicity (ADCC) Responses. Curr. HIV Res., 11(5):378-387, Jul 2013. PubMed ID: 24191939. Show all entries for this paper.