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Displaying record number 1916

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MAb ID	m44
HXB2 Location	Env	Env Epitope Map
Author Location	gp41
Epitope
Ab Type	C-HR
Neutralizing
Species (Isotype)	human
Patient
Immunogen	HIV-1 infection
Keywords	ADCC

Notes

Showing 1 matching of 3 total notes.

m44: Isolation of human mAb, E10, from an HIV-1-infected patient sample by single B cell sorting and single cell PCR has been reported. E10 showed binding to gp140 trimer and linear peptides derived from gp41 membrane proximal external region (MPER). E Mab E10 showed less reactivity with human self-antigens e.g., phospholipids, including CL, Ro (SSA), centromere B, and histones in comparison with m44 when measured by AtheNA antinuclear autoantibody assay. m44 didn't bind to CL Yang2018 (ADCC)

References

Showing 1 matching of 3 total references.

Yang2018 Zheng Yang, Xi Liu, Zehua Sun, Jingjing Li, Weiguo Tan, Weiye Yu, and Meiyun Zhang. Identification of a HIV gp41-Specific Human Monoclonal Antibody with Potent Antibody-Dependent Cellular Cytotoxicity. Front. Immunol., 9:2613, 2018. PubMed ID: 30519238. Show all entries for this paper.