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HIV Molecular Immunology Database

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Displaying record number 3959

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MAb ID Tri-NAb
HXB2 Location Env Env Epitope Map
Author Location  
Epitope
Ab Type gp120 CD4bs, gp120 V3 // V3 glycan (V3g), gp41 MPER (membrane proximal external region)
Neutralizing P(tier 2)  View neutralization details
Species (Isotype) human(IgG)
Patient Donor 17, Donor N152, NIH45
Immunogen  
Keywords antibody generation, bispecific/trispecific, immunotherapy, neutralization

Notes

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References

Showing 1 of 1 reference.

Isolation Paper
Steinhardt2018 James J. Steinhardt, Javier Guenaga, Hannah L. Turner, Krisha McKee, Mark K. Louder, Sijy O'Dell, Chi-I Chiang, Lin Lei, Andrey Galkin, Alexander K. Andrianov, Nicole A. Doria-Rose, Robert T. Bailer, Andrew B. Ward, John R. Mascola, and Yuxing Li. Rational Design of a Trispecific Antibody Targeting the HIV-1 Env with Elevated Anti-Viral Activity. Nat. Commun., 9(1):877, 28 Feb 2018. PubMed ID: 29491415. Show all entries for this paper.


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