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MAb ID | PCT64-24H (PCT64 24H) | |
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HXB2 Location | Env | Env Epitope Map |
Author Location | Env | |
Epitope |
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Subtype | A1 | |
Ab Type | gp120 V2 // V2 glycan(V2g) // V2 apex | |
Neutralizing | P View neutralization details | |
Species (Isotype) | human(IgG) | |
Patient | PC64 | |
Immunogen | HIV-1 infection | |
Country | Rwanda | |
Keywords | antibody binding site, antibody generation, antibody lineage, antibody sequence, binding affinity, neutralization |
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Isolation Paper
Landais2017
Elise Landais, Ben Murrell, Bryan Briney, Sasha Murrell, Kimmo Rantalainen, Zachary T. Berndsen, Alejandra Ramos, Lalinda Wickramasinghe, Melissa Laird Smith, Kemal Eren, Natalia de Val, Mengyu Wu, Audrey Cappelletti, Jeffrey Umotoy, Yolanda Lie, Terri Wrin, Paul Algate, Po-Ying Chan-Hui, Etienne Karita, IAVI Protocol C Investigators, IAVI African HIV Research Network, Andrew B. Ward, Ian A. Wilson, Dennis R. Burton, Davey Smith, Sergei L. Kosakovsky Pond, and Pascal Poignard. HIV Envelope Glycoform Heterogeneity and Localized Diversity Govern the Initiation and Maturation of a V2 Apex Broadly Neutralizing Antibody Lineage. Immunity, 47(5):990-1003.e9, 21 Nov 2017. PubMed ID: 29166592.
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