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Displaying record number 3656

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MAb ID DH511.2 (DH512, Ab510049)
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope
Subtype C
Ab Type gp41 MPER (membrane proximal external region)
Neutralizing P (tier 2)  View neutralization details
Contacts and Features View contacts and features
Species (Isotype) human(IgG)
Patient CH0210
Immunogen HIV-1 infection
Country South Africa
Keywords acute/early infection, antibody binding site, antibody generation, antibody lineage, antibody polyreactivity, antibody sequence, broad neutralizer, computational prediction, contact residues, germline, mother-to-infant transmission, neutralization, structure, transmission pair, vaccine antigen design

Notes

Showing 6 of 6 notes.

References

Showing 6 of 6 references.

Isolation Paper
Williams2017 LaTonya D. Williams, Gilad Ofek, Sebastian Schätzle, Jonathan R. McDaniel, Xiaozhi Lu, Nathan I. Nicely, Liming Wu, Caleb S. Lougheed, Todd Bradley, Mark K. Louder, Krisha McKee, Robert T. Bailer, Sijy O'Dell, Ivelin S. Georgiev, Michael S. Seaman, Robert J. Parks, Dawn J. Marshall, Kara Anasti, Guang Yang, Xiaoyan Nie, Nancy L. Tumba, Kevin Wiehe, Kshitij Wagh, Bette Korber, Thomas B. Kepler, S. Munir Alam, Lynn Morris, Gift Kamanga, Myron S. Cohen, Mattia Bonsignori, Shi-Mao Xia, David C. Montefiori, Garnett Kelsoe, Feng Gao, John R. Mascola, M. Anthony Moody, Kevin O. Saunders, Hua-Xin Liao, Georgia D. Tomaras, George Georgiou, and Barton F. Haynes. Potent and Broad HIV-Neutralizing Antibodies in Memory B Cells and Plasma. Sci. Immunol., 2(7), 27 Jan 2017. PubMed ID: 28783671. Show all entries for this paper.

Bricault2019 Christine A. Bricault, Karina Yusim, Michael S. Seaman, Hyejin Yoon, James Theiler, Elena E. Giorgi, Kshitij Wagh, Maxwell Theiler, Peter Hraber, Jennifer P. Macke, Edward F. Kreider, Gerald H. Learn, Beatrice H. Hahn, Johannes F. Scheid, James M. Kovacs, Jennifer L. Shields, Christy L. Lavine, Fadi Ghantous, Michael Rist, Madeleine G. Bayne, George H. Neubauer, Katherine McMahan, Hanqin Peng, Coraline Chéneau, Jennifer J. Jones, Jie Zeng, Christina Ochsenbauer, Joseph P. Nkolola, Kathryn E. Stephenson, Bing Chen, S. Gnanakaran, Mattia Bonsignori, LaTonya D. Williams, Barton F. Haynes, Nicole Doria-Rose, John R. Mascola, David C. Montefiori, Dan H. Barouch, and Bette Korber. HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host Microbe, 25(1):59-72.e8, 9 Jan 2019. PubMed ID: 30629920. Show all entries for this paper.

Haynes2016a B. F. Haynes, H. X. Liao, M. A. Moody, L. Williams, K. J. Wiehe, and G. A. Ofek. HIV-1 Neutralizing Antibodies and Uses Thereof. WIPO patent application, Sep 2016. URL: https://patentscope.wipo.int/search/en/detail.jsf?docId=WO2016149710. Application number PCT/US2016/023488. Show all entries for this paper.

Kumar2018 Amit Kumar, Claire E. P. Smith, Elena E. Giorgi, Joshua Eudailey, David R. Martinez, Karina Yusim, Ayooluwa O. Douglas, Lisa Stamper, Erin McGuire, Celia C. LaBranche, David C. Montefiori, Genevieve G. Fouda, Feng Gao, and Sallie R. Permar. Infant Transmitted/Founder HIV-1 Viruses from Peripartum Transmission Are Neutralization Resistant to Paired Maternal Plasma. PLoS Pathog., 14(4):e1006944, Apr 2018. PubMed ID: 29672607. Show all entries for this paper.

Wiehe2018 Kevin Wiehe, Todd Bradley, R. Ryan Meyerhoff, Connor Hart, Wilton B. Williams, David Easterhoff, William J. Faison, Thomas B. Kepler, Kevin O. Saunders, S. Munir Alam, Mattia Bonsignori, and Barton F. Haynes. Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development. Cell Host Microbe, 23(6):759-765.e6, 13 Jun 2018. PubMed ID: 29861171. Show all entries for this paper.

Zhang2019a Lei Zhang, Adriana Irimia, Lingling He, Elise Landais, Kimmo Rantalainen, Daniel P. Leaman, Thomas Vollbrecht, Armando Stano, Daniel I. Sands, Arthur S. Kim, IAVI Protocol G Investigators, Pascal Poignard, Dennis R. Burton, Ben Murrell, Andrew B. Ward, Jiang Zhu, Ian A. Wilson, and Michael B. Zwick. An MPER Antibody Neutralizes HIV-1 Using Germline Features Shared Among Donors. Nat. Commun., 10(1):5389, 26 Nov 2019. PubMed ID: 31772165. Show all entries for this paper.


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