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Displaying record number 2971

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MAb ID N5-i5
HXB2 Location Env Env Epitope Map
Author Location gp120
Epitope (Discontinuous epitope)
Ab Type gp120 CD4i cluster A
Neutralizing no
Species (Isotype) human(IgG)
Patient N5
Immunogen HIV-1 infection
Country United States
Keywords ADCC, antibody binding site, antibody generation, antibody interactions, binding affinity, neutralization, review, structure

Notes

Showing 5 of 5 notes.

References

Showing 5 of 5 references.

Isolation Paper
Guan2013 Yongjun Guan, Marzena Pazgier, Mohammad M. Sajadi, Roberta Kamin-Lewis, Salma Al-Darmarki, Robin Flinko, Elena Lovo, Xueji Wu, James E. Robinson, Michael S. Seaman, Timothy R. Fouts, Robert C. Gallo, Anthony L. DeVico, and George K. Lewis. Diverse Specificity and Effector Function Among Human Antibodies to HIV-1 Envelope Glycoprotein Epitopes Exposed by CD4 Binding. Proc. Natl. Acad. Sci. U.S.A., 110(1):E69-E78, 2 Jan 2013. PubMed ID: 23237851. Show all entries for this paper.

Acharya2014 Priyamvada Acharya, William D. Tolbert, Neelakshi Gohain, Xueji Wu, Lei Yu, Tongyun Liu, Wensheng Huang, Chih-chin Huang, Young Do Kwon, Robert K. Louder, Timothy S. Luongo, Jason S. McLellan, Marie Pancera, Yongping Yang, Baoshan Zhang, Robin Flinko, James S. Foulke, Jr., Mohammad M. Sajadi, Roberta Kamin-Lewis, James E. Robinson, Loïc Martin, Peter D. Kwong, Yongjun Guan, Anthony L. DeVico, George K. Lewis, and Marzena Pazgier. Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J. Virol., 88(21):12895-12906, Nov 2014. PubMed ID: 25165110. Show all entries for this paper.

Ding2015 Shilei Ding, Maxime Veillette, Mathieu Coutu, Jérémie Prévost, Louise Scharf, Pamela J. Bjorkman, Guido Ferrari, James E. Robinson, Christina Stürzel, Beatrice H. Hahn, Daniel Sauter, Frank Kirchhoff, George K. Lewis, Marzena Pazgier, and Andrés Finzi. A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies. J. Virol., 90(4):2127-2134, Feb 2016. PubMed ID: 26637462. Show all entries for this paper.

Pollara2013 Justin Pollara, Mattia Bonsignori, M. Anthony Moody, Marzena Pazgier, Barton F. Haynes, and Guido Ferrari. Epitope Specificity of Human Immunodeficiency Virus-1 Antibody Dependent Cellular Cytotoxicity (ADCC) Responses. Curr. HIV Res., 11(5):378-387, Jul 2013. PubMed ID: 24191939. Show all entries for this paper.

Veillette2014 Maxime Veillette, Anik Désormeaux, Halima Medjahed, Nour-Elhouda Gharsallah, Mathieu Coutu, Joshua Baalwa, Yongjun Guan, George Lewis, Guido Ferrari, Beatrice H. Hahn, Barton F. Haynes, James E. Robinson, Daniel E. Kaufmann, Mattia Bonsignori, Joseph Sodroski, and Andres Finzi. Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity. J. Virol., 88(5):2633-2644, Mar 2014. PubMed ID: 24352444. Show all entries for this paper.


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