HIV molecular immunology database
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|MAb ID||5025A (5025)|
|gp160 Epitope Map|
|Author Location||gp120(313-317 BH10)|
|Research Contact||Paul Durda, Du Pont de Nemours and Co|
|Ab Type||gp120 V3 // V3 glycan (V3g)|
|Keywords||antibody binding site, antibody generation, binding affinity|
|Vaccine strain||B clade BH10|
|Vaccine component||Env V3|
Showing 2 of 2 notes.
Showing 2 of 2 references.
DSouza1991 M. P. D'Souza, P. Durda, C. V. Hanson, G. Milman, and Collaborating Investigators. Evaluation of Monoclonal Antibodies to HIV-1 by Neutralization and Serological Assays: An International Collaboration. AIDS, 5:1061-1070, 1991. PubMed ID: 1718320. Show all entries for this paper.
Langedijk1991 J. P. M. Langedijk, N. K. T. Back, P. J. Durda, J. Goudsmit, and R. H. Meloen. Neutralizing activity of anti-peptide antibodies against the principal neutralization domain of human immunodeficiency virus type 1. J. Gen. Virol., 72:2519-2526, 1991. MAbs were raised against RIQRGPGRAFVTIGK by immunizing mice. Fine structure of MAb binding sites was mapped using pepscan. Preservation of the $\beta$ turn at the tip of the loop was critical. PubMed ID: 1919529. Show all entries for this paper.