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Displaying record number 42

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MAb ID	25.3
HXB2 Location	Gag(214-234) DNA(1429..1491)	Gag Epitope Map
Author Location	p24(82-102)
Epitope	`RVHPVHAGPIAPGQMREPRGS`	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1κ)
Patient
Immunogen
Keywords

Notes

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25.3: Crystal structure of the CA protein bound to Fab 25.3 was solved -- monomers form 7 alpha-helices arranged in a coiled-coil -- Fab binds to a long antigenic peptide that separates the longest helices, with a salt bridge at CA 82 R, and interactions as far away as positions 100 and 102. Momany1996

References

Showing 1 of 1 reference.

Momany1996 C. Momany, L. C. Kovari, A. J. Prongay, W. Keller, R. K. Gitti, B. M. Lee, A. E. Gorbalenya, L. Tong, J. McClure, L. S. Ehrlich, M. F. Summers, C. Carter, and M. G. Rossman. Crystal Structure of Dimeric HIV-1 Capsid Protein. Nat. Struct. Biol., 3:763-770, 1996. PubMed ID: 8784350. Show all entries for this paper.