HIV molecular immunology database
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|gp160 Epitope Map|
|Author Location||gp120(310-315 BH10)|
|Ab Type||gp120 V3 // V3 glycan (V3g)|
|Keywords||antibody binding site, antibody generation, binding affinity|
|Vaccine strain||B clade BH10|
|Vaccine component||Env V3|
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Langedijk1991 J. P. M. Langedijk, N. K. T. Back, P. J. Durda, J. Goudsmit, and R. H. Meloen. Neutralizing activity of anti-peptide antibodies against the principal neutralization domain of human immunodeficiency virus type 1. J. Gen. Virol., 72:2519-2526, 1991. MAbs were raised against RIQRGPGRAFVTIGK by immunizing mice. Fine structure of MAb binding sites was mapped using pepscan. Preservation of the $\beta$ turn at the tip of the loop was critical. PubMed ID: 1919529. Show all entries for this paper.