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MAb ID polyclonal
HXB2 Location gp160(305-319)
DNA(7137..7181)
gp160 Epitope Map
Author Location gp120(305- LAI)
Epitope KSIHIGPGRAFYT Epitope Alignment
KSIHIGPGRAFYT epitope logo
Subtype B
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing  
Species (Isotype) human(IgG, IgM)
Patient  
Immunogen HIV-1 infection
Keywords antibody binding site, binding affinity, escape, mutation acquisition

Notes

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References

Showing 1 of 1 reference.

Langedijk1995 J. P. M. Langedijk, G. Zwart, J. Goudsmit, and R. H. Meloen. Fine Specificity of Antibody Recognition May Predict Amino Acid Substitution in the Third Variable Region of gp120 during HIV Type 1 Infection. AIDS Res. Hum. Retroviruses, 11:1153-1162, 1995. To investigate how HIV-1 escapes from recognition, a panel of V3 peptides based on sequences derived from 6 HIV-1 positive individuals was tested for reactivity with autologous sera sampled over time. The V3 region undergoes immune escape through mutation. PubMed ID: 8573370. Show all entries for this paper.


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