HIV molecular immunology database

 

Search Antibody Database

Found 3 matching records:

Displaying record number 401

Download this epitope record as JSON.

MAb ID F19.48-3
HXB2 Location gp160(307-319)
DNA(7143..7181)
gp160 Epitope Map
Author Location gp120(312-324 LAI)
Epitope IRIQRGPGRAFVT Epitope Alignment
IRIQRGPGRAFVT epitope logo
Subtype B
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing L
Species (Isotype) mouse(IgG2aκ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade IIIB
Vaccine component gp120

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Boudet1994 F. Boudet, J. Theze, and M. Zouali. Anti-Idiotypic Antibodies to the Third Variable Domain of gp120 Induce an Anti-HIV-1 Antibody Response in Mice. Virology, 200:176-188, 1994. PubMed ID: 7510435. Show all entries for this paper.


Displaying record number 402

Download this epitope record as JSON.

MAb ID F19.26-4
HXB2 Location gp160(307-319)
DNA(7143..7181)
gp160 Epitope Map
Author Location gp120(312-324 LAI)
Epitope IRIQRGPGRAFVT Epitope Alignment
IRIQRGPGRAFVT epitope logo
Subtype B
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing L
Species (Isotype) mouse(IgG2aκ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade IIIB
Vaccine component gp120

Notes

Showing 1 of 1 note.

References

Showing 1 of 1 reference.

Boudet1994 F. Boudet, J. Theze, and M. Zouali. Anti-Idiotypic Antibodies to the Third Variable Domain of gp120 Induce an Anti-HIV-1 Antibody Response in Mice. Virology, 200:176-188, 1994. PubMed ID: 7510435. Show all entries for this paper.


Displaying record number 403

Download this epitope record as JSON.

MAb ID F19.57-11
HXB2 Location gp160(307-319)
DNA(7143..7181)
gp160 Epitope Map
Author Location gp120(312-324 LAI)
Epitope IRIQRGPGRAFVT Epitope Alignment
IRIQRGPGRAFVT epitope logo
Subtype B
Ab Type gp120 V3 // V3 glycan (V3g)
Neutralizing L (LAI)
Species (Isotype) mouse(IgG1κ)
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein
Vaccine strain B clade IIIB
Vaccine component gp120

Notes

Showing 2 of 2 notes.

References

Showing 3 of 3 references.

Boudet1991 F. Boudet, J. Theze, and M. Zouali. UV-Treated Polystyrene Microtitre Plates for Use in an ELISA to Measure Antibodies against Synthetic Peptides. J. Immunol. Methods, 142:73-82, 1991. PubMed ID: 1717595. Show all entries for this paper.

Boudet1994 F. Boudet, J. Theze, and M. Zouali. Anti-Idiotypic Antibodies to the Third Variable Domain of gp120 Induce an Anti-HIV-1 Antibody Response in Mice. Virology, 200:176-188, 1994. PubMed ID: 7510435. Show all entries for this paper.

Boudet1995 F. Boudet, H. Keller, M. P. Kieny, and J. Theze. Single Peptide and Anti-Idiotype Based Immunizations Can Broaden the Antibody Response against the Variable V3 Domain of HIV-1 in Mice. Mol. Immunol., 32:449-457, 1995. Given the high degree of sequence variability of the V3 loop, the humoral response to this region tends to be type specific. An anti-idiotypic antibody could broaden the anti-V3 antibody polyclonal response in BALB/c mice, relative to the original Ab used to generate the anti-idiotype response. A synthetic peptide derived from the V3 determinant of HIV-1 MN induced an antibody response to multiple HIV-1 strains, but the extent of this cross-reactivity was inversely correlated with the binding affinity to V3 MN peptide. PubMed ID: 7783749. Show all entries for this paper.


Questions or comments? Contact us at immuno@lanl.gov
 
Managed by Triad National Security, LLC for the U.S. Department of Energy’s National Nuclear Security Administration
Copyright © 2022 Triad National Security, LLC | Disclaimer/Privacy

Dept of Health & Human Services Los Alamos National Institutes of Health