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Displaying record number 302

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MAb ID GV1A8
HXB2 Location gp160(105-113)
DNA(6537..6563)
gp160 Epitope Map
Author Location gp120(105-113 IIIB)
Epitope HEDIISLWD Epitope Alignment
HEDIISLWD epitope logo
Ab Type gp120 C1
Neutralizing  
Species (Isotype) mouse
Patient  
Immunogen vaccine
Keywords  

Vaccine Details

Vaccine type protein-Ab complex
Vaccine component gp120-Mab complex

Notes

Showing 2 of 2 notes.

References

Showing 2 of 2 references.

Denisova1996 G. Denisova, B. Stern, D. Raviv, J. Zwickel, N. I. Smorodinsky, and J. M. Gershoni. Humoral Immune Response to Immunocomplexed HIV Envelope Glycoprotein 120. AIDS Res. Hum. Retroviruses, 12:901-909, 1996. Mice were injected with the gp120 in different configurations: free, complexed with CD4, and as an immunocomplex bound to a V3 loop MAb (M77) of the protein. Polyclonal sera, as well as monoclonal antibodies produced in each case, were analyzed. The free gp120 and gp120-CD4 complex immunogens stimulated responses were directed mainly toward conformational epitopes, but gp120 immunocomplexed with MAb M77 also produced numerous and varied MAbs directed toward linear epitopes that were presumably inaccessible on the gp120, gp120-CD4 proteins. PubMed ID: 8798975. Show all entries for this paper.

Kanduc2008 Darja Kanduc, Rosario Serpico, Alberta Lucchese, and Yehuda Shoenfeld. Correlating Low-Similarity Peptide Sequences and HIV B-Cell Epitopes. Autoimmun. Rev., 7(4):291-296, Feb 2008. PubMed ID: 18295732. Show all entries for this paper.


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