Search Antibody Database

Found 1 matching record:

Displaying record number 95

Download this epitope record as JSON.

MAb ID	RL4.72.1
HXB2 Location	Gag(219-233) DNA(1444..1488)	Gag Epitope Map
Author Location	p24(219-233 BRU)
Epitope	`HAGPIAPGQMREPRG`	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Vaccine type	inactivated HIV
Vaccine strain	D clade NDK
Vaccine component	HIV-1

Notes

Showing 2 of 2 notes.

RL4.72.1: Similarity level of the RL4.72.1 binding site pentapeptide PGQMR to the host proteome was low, with the low-similarity 5-mer occurring in the host proteome 0 times, indicating that this peptide can be used to elicit Abs for active/passive immunotherapy with low risk of cross-reaction with the host proteome. Kanduc2008
RL4.72.1: Immunized with inactivated HIV NDK, D clade, reacts with B clade peptide. RobertHebmann1992b

References

Showing 4 of 4 references.

Tatsumi1990 M. Tatsumi, C. Devaux, F. Kourilsky, and J. C. Chermann. Characterization of monoclonal antibodies directed against distinct conserved epitopes of human immunodeficiency virus type 1 core proteins. Mol Cell Biochem, 96:127-136, 1990. PubMed ID: 1703272. Show all entries for this paper.

RobertHebmann1992a V. Robert-Hebmann, S. Emiliani, M. Resnicoff, F. Jean, and C. Devaux. Subtyping of human immunodeficiency virus isolates with a panel of monoclonal antibodies: identification of conserved and divergent epitopes on p17 and p25 core proteins. Mol. Immunol., 29:1175-1183, 1992. PubMed ID: 1382219. Show all entries for this paper.

RobertHebmann1992b V. Robert-Hebmann, S. Emiliani, F. Jean, M. Resnicoff, and C. Devaux. Clonal Analysis of Murine B-Cell Response to the Human Immunodeficiency Virus Type 1 (HIV-1)-gag p17 and p25 Antigens. Mol. Immunol., 29:729-738, 1992. PubMed ID: 1376412. Show all entries for this paper.

Kanduc2008 Darja Kanduc, Rosario Serpico, Alberta Lucchese, and Yehuda Shoenfeld. Correlating Low-Similarity Peptide Sequences and HIV B-Cell Epitopes. Autoimmun. Rev., 7(4):291-296, Feb 2008. PubMed ID: 18295732. Show all entries for this paper.