HIV molecular immunology database


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Displaying record number 56

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MAb ID CD-4/1 (CB-4/1/1/F6)
HXB2 Location Gag(178-188)
Gag Epitope Map
Author Location p24(182-197)
Epitope GATPQDLNTML Epitope Alignment
GATPQDLNTML epitope logo
Ab Type  
Species (Isotype) mouse(IgG2aκ)
Immunogen vaccine

Vaccine Details

Vaccine type beta-galactosidase fusion protein
Vaccine component p24 Gag


Showing 4 of 4 notes.


Showing 5 of 5 references.

Grunow1990 R. Grunow, R. Giess, T. Portsman, H. Dopel, K. Hansel, and R. von Baehr. Development and Biological Testing of Human and Murine Antibodies against HIV Antigens. Z. Klin. Med., 45:367-369, 1990. Show all entries for this paper.

Franke1992 L. Franke, R. Grunow, R. Meissner, T. Portsman, and R. von Baehr. Inhibition of HIV-1 Infection In Vitro by Murine Monoclonal Anti-p24 Antibodies. J. Med. Virol., 37:137-142, 1992. PubMed ID: 1629712. Show all entries for this paper.

Hohne1993 W. E. Hohne, G. Kuttner, S. Kiessig, G. Housdorf, R. Grunow, K. Winkler, H. Wessner, E. Giessmann, R. Stieger, J. Schneider-Mergener, R. von Baehr, and D. Schomburg. Structural Base of the Interaction of a Monoclonal Antibody against p24 of HIV-1 with Its Peptide Epitope. Mol. Immunol., 30:1213-1221, 1993. PubMed ID: 7692237. Show all entries for this paper.

Glaser1996 R. W. Glaser and G. Hausdorf. Binding Kinetics of an Antibody against HIV p24 Core Protein Measured with Real-Time Biomolecular Interaction Analysis Suggest a Slow Conformational Change in Antigen p24. J. Immunol. Methods, 189:1-14, 1996. The MAb CD-4/1 and p24 have unusual biphasic kinetics of association. PubMed ID: 8576571. Show all entries for this paper.

Ehrhard1996 B. Ehrhard, R. Misselwitz, K. Welfle, G. Hausdorf, R. W. Glaser, J. Schneider-Mergener, and H. Welfle. Chemical Modification of Recombinant HIV-1 Capsid Protein p24 Leads to the Release of a Hidden Epitope Prior to Changes of the Overall Folding of the Protein. Biochemistry, 35:9097-9105, 1996. PubMed ID: 8703914. Show all entries for this paper.

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