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Displaying record number 75

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MAb ID	111/073
HXB2 Location	Gag(203-213) DNA(1396..1428)	Gag Epitope Map
Author Location	p24(203-213 IIIB)
Epitope	ETINEEAAEWD	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Notes

Showing 1 of 1 note.

• 111/073: cross-reactive between HIV-1, HIV-2 and SIV MAC by multiple assays. Niedrig1991

References

Showing 1 of 1 reference.

Niedrig1991 M. Niedrig, J. Hinkula, H.-P. Harthus, M. Broker, L. Hopp, G. Pauli, and B. Wahren. Characterization of murine monoclonal antibodies directed against the core proteins of human immunodeficiency virus types 1 and 2. J. Virol., 65:4529-4533, 1991. Multiple anti-HIV p24 MAbs were generated using HIV-1 IIIB p24 or HIV-2 ROD p26 as immunogens. The epitopes for these MAbs were mapped, and the cross-reactivity between HIV-1 IIIB, HIV-2 ROD and SIV MAC antigens were compared using multiple antibody binding assays. While some of the antibodies raised were cross-reactive by some or all of the assays, (ELISA, WB, immunofluorescence, immunoprecipitation and alkaline phosphatase anti-alkaline phosphatase assay), the different assays often gave different results. Only the antibodies raised to HIV-1 IIIB p24 are included in this database. PubMed ID: 1712863. Show all entries for this paper.

Displaying record number 74

Download this epitope record as JSON.

MAb ID	113/038
HXB2 Location	Gag(203-213) DNA(1396..1428)	Gag Epitope Map
Author Location	p24(203-213 IIIB)
Epitope	ETINEEAAEWD	Epitope Alignment
Ab Type
Neutralizing
Species (Isotype)	mouse(IgG1)
Patient
Immunogen	vaccine
Keywords

Vaccine Details

Notes

Showing 1 of 1 note.

• 113/038: cross-reactive between HIV-1, HIV-2 and SIV MAC by multiple assays. Niedrig1991

References

Showing 1 of 1 reference.

Niedrig1991 M. Niedrig, J. Hinkula, H.-P. Harthus, M. Broker, L. Hopp, G. Pauli, and B. Wahren. Characterization of murine monoclonal antibodies directed against the core proteins of human immunodeficiency virus types 1 and 2. J. Virol., 65:4529-4533, 1991. Multiple anti-HIV p24 MAbs were generated using HIV-1 IIIB p24 or HIV-2 ROD p26 as immunogens. The epitopes for these MAbs were mapped, and the cross-reactivity between HIV-1 IIIB, HIV-2 ROD and SIV MAC antigens were compared using multiple antibody binding assays. While some of the antibodies raised were cross-reactive by some or all of the assays, (ELISA, WB, immunofluorescence, immunoprecipitation and alkaline phosphatase anti-alkaline phosphatase assay), the different assays often gave different results. Only the antibodies raised to HIV-1 IIIB p24 are included in this database. PubMed ID: 1712863. Show all entries for this paper.